Experiment: 7H9 with Linezolid 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2553c and Rv2554c overlap by 8 nucleotides Rv2554c and Rv2555c are separated by 0 nucleotides Rv2555c and Rv2556c are separated by 90 nucleotides Rv2556c and Rv2557 are separated by 106 nucleotides
Rv2553c: Rv2553c - Probable conserved membrane protein, at 2,872,012 to 2,873,265
Rv2553c
Rv2554c: Rv2554c - Conserved protein, at 2,873,258 to 2,873,770
Rv2554c
Rv2555c: Rv2555c - Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS), at 2,873,771 to 2,876,485
Rv2555c
Rv2556c: Rv2556c - Conserved hypothetical protein, at 2,876,576 to 2,876,965
Rv2556c
Rv2557: Rv2557 - Conserved protein, at 2,877,072 to 2,877,746
Rv2557
Position (kb)
2873
2874
2875
2876
2877 Strain fitness (log2 ratio)
-2
-1
0
1 at 2872.875 kb on - strand, within Rv2553c at 2876.512 kb on - strand at 2876.541 kb on - strand at 2876.541 kb on - strand at 2876.743 kb on - strand, within Rv2556c at 2876.837 kb on - strand, within Rv2556c at 2876.989 kb on + strand at 2876.990 kb on - strand at 2877.067 kb on - strand at 2877.147 kb on - strand, within Rv2557 at 2877.147 kb on - strand, within Rv2557 at 2877.204 kb on - strand, within Rv2557 at 2877.242 kb on - strand, within Rv2557 at 2877.332 kb on - strand, within Rv2557 at 2877.478 kb on + strand, within Rv2557 at 2877.478 kb on + strand, within Rv2557 at 2877.479 kb on - strand, within Rv2557
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.3 ug/mL remove 2,872,875 - Rv2553c 0.69 -2.0 2,876,512 - -0.1 2,876,541 - -0.1 2,876,541 - -0.3 2,876,743 - Rv2556c 0.43 +0.0 2,876,837 - Rv2556c 0.67 -0.4 2,876,989 + -0.1 2,876,990 - -0.8 2,877,067 - -0.8 2,877,147 - Rv2557 0.11 +0.2 2,877,147 - Rv2557 0.11 +0.1 2,877,204 - Rv2557 0.20 +0.0 2,877,242 - Rv2557 0.25 -2.0 2,877,332 - Rv2557 0.39 +0.3 2,877,478 + Rv2557 0.60 -0.1 2,877,478 + Rv2557 0.60 -0.3 2,877,479 - Rv2557 0.60 -0.5
Or see this region's nucleotide sequence