Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2300c

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
2,571,203	+		Rv2299c	0.59	+0.2
2,571,203	+		Rv2299c	0.59	+0.7
2,571,215	+		Rv2299c	0.59	-0.6
2,571,215	+		Rv2299c	0.59	-0.3
2,571,215	+		Rv2299c	0.59	-0.3
2,571,216	-		Rv2299c	0.60	+0.7
2,571,402	+		Rv2299c	0.69	+0.6
2,571,425	+		Rv2299c	0.70	-0.3
2,571,425	+		Rv2299c	0.70	+0.1
2,571,516	-		Rv2299c	0.75	-0.3
2,571,516	-		Rv2299c	0.75	+1.7
2,571,611	+		Rv2299c	0.80	-0.1
2,571,772	-		Rv2299c	0.88	+0.1
2,571,872	-				+0.2
2,571,918	+				-1.3
2,571,918	+				-0.6
2,571,919	-				-0.5
2,571,919	-				-0.8
2,572,022	+				+0.9
2,572,022	+				-0.6
2,572,023	-				-0.2
2,572,023	-				-0.8
2,572,101	+				-0.5
2,572,101	+				-0.5
2,572,133	+				+0.7
2,572,133	+				+0.6
2,572,134	-				-0.1
2,572,134	-				+0.2
2,572,134	-				-1.1
2,572,134	-				+0.8
2,572,202	-		Rv2300c	0.14	-1.0
2,572,203	+		Rv2300c	0.14	-0.1
2,572,204	-		Rv2300c	0.14	-2.9
2,572,204	-		Rv2300c	0.14	+0.1
2,572,204	-		Rv2300c	0.14	-0.6
2,572,275	+		Rv2300c	0.21	+0.7
2,572,275	+		Rv2300c	0.21	+0.3
2,572,275	+		Rv2300c	0.21	+1.4
2,572,276	-		Rv2300c	0.21	-0.2
2,572,325	+		Rv2300c	0.27	-0.9
2,572,706	+		Rv2300c	0.68	-0.0
2,572,712	+		Rv2300c	0.68	+1.0
2,572,802	+		Rv2300c	0.78	+0.2
2,572,802	+		Rv2300c	0.78	-0.1
2,572,803	-		Rv2300c	0.78	+0.8
2,572,889	+		Rv2300c	0.87	+0.7
2,572,889	+		Rv2300c	0.87	-0.4
2,572,890	-		Rv2300c	0.87	+0.5
2,572,890	-		Rv2300c	0.87	+0.9
2,572,890	-		Rv2300c	0.87	-1.0
2,572,890	-		Rv2300c	0.87	+1.0
2,572,890	-		Rv2300c	0.87	-1.3
2,572,894	+		Rv2300c	0.88	-0.7
2,572,894	+		Rv2300c	0.88	-0.4
2,572,894	+		Rv2300c	0.88	-0.2
2,572,894	+		Rv2300c	0.88	+2.3
2,572,894	+		Rv2300c	0.88	+0.5
2,572,895	-		Rv2300c	0.88	-0.1
2,572,895	-		Rv2300c	0.88	-0.4
2,572,895	-		Rv2300c	0.88	-0.2
2,572,895	-		Rv2300c	0.88	-0.4
2,572,895	-		Rv2300c	0.88	-0.2
2,573,004	-				-0.8
2,573,004	-				-0.4
2,573,025	+				-0.1
2,573,025	+				-0.2
2,573,026	-				-0.6
2,573,089	+		Rv2301	0.11	+0.7
2,573,090	-		Rv2301	0.11	+1.7
2,573,090	-		Rv2301	0.11	+1.1
2,573,264	+		Rv2301	0.36	+0.2
2,573,265	-		Rv2301	0.36	-0.1
2,573,277	-		Rv2301	0.38	-0.3
2,573,410	-		Rv2301	0.57	+0.5
2,573,410	-		Rv2301	0.57	+0.3
2,573,410	-		Rv2301	0.57	+1.1
2,573,544	-		Rv2301	0.76	+1.1
2,573,648	+				+0.8
2,573,648	+				+1.7
2,573,648	+				-0.2
2,573,649	-				+1.1
2,573,649	-				-0.8
2,573,649	-				-0.9
2,573,649	-				-0.3
2,573,649	-				+1.7
2,573,705	+				+0.4
2,573,706	-				-0.4
2,573,706	-				-0.8
2,573,713	+				+0.5
2,573,713	+				-0.3
2,573,714	-				-0.9
2,573,788	+				+1.7
2,573,788	+				-0.2
2,573,789	-				+0.4
2,573,808	-				-0.4
2,573,808	-				+0.8
2,573,835	-				-1.1
2,573,922	-		Rv2302	0.45	+0.8
2,573,922	-		Rv2302	0.45	-0.8