Experiment: 7H9 with Linezolid 0.3 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1967 and Rv1968 overlap by 4 nucleotides Rv1968 and Rv1969 overlap by 4 nucleotides
Rv1967: Rv1967 - Mce-family protein Mce3B, at 2,210,601 to 2,211,629
Rv1967
Rv1968: Rv1968 - Mce-family protein Mce3C, at 2,211,626 to 2,212,858
Rv1968
Rv1969: Rv1969 - Mce-family protein Mce3D, at 2,212,855 to 2,214,126
Rv1969
Position (kb)
2211
2212
2213 Strain fitness (log2 ratio)
-1
0
1
2 at 2210.653 kb on + strand at 2210.654 kb on - strand at 2210.721 kb on + strand, within Rv1967 at 2210.722 kb on - strand, within Rv1967 at 2210.724 kb on + strand, within Rv1967 at 2210.724 kb on + strand, within Rv1967 at 2210.725 kb on - strand, within Rv1967 at 2210.725 kb on - strand, within Rv1967 at 2211.272 kb on - strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.447 kb on + strand, within Rv1967 at 2211.448 kb on - strand, within Rv1967 at 2211.483 kb on + strand, within Rv1967 at 2211.483 kb on + strand, within Rv1967 at 2211.511 kb on - strand, within Rv1967 at 2211.511 kb on - strand, within Rv1967 at 2211.531 kb on + strand at 2211.583 kb on - strand at 2211.583 kb on - strand at 2211.713 kb on + strand at 2212.019 kb on + strand, within Rv1968 at 2212.124 kb on - strand, within Rv1968 at 2212.544 kb on + strand, within Rv1968 at 2212.544 kb on + strand, within Rv1968 at 2212.544 kb on + strand, within Rv1968 at 2212.545 kb on - strand, within Rv1968 at 2212.545 kb on - strand, within Rv1968 at 2213.102 kb on - strand, within Rv1969 at 2213.102 kb on - strand, within Rv1969 at 2213.216 kb on + strand, within Rv1969 at 2213.217 kb on - strand, within Rv1969
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.3 ug/mL remove 2,210,653 + +1.0 2,210,654 - -0.0 2,210,721 + Rv1967 0.12 -0.5 2,210,722 - Rv1967 0.12 +0.1 2,210,724 + Rv1967 0.12 -0.9 2,210,724 + Rv1967 0.12 +0.1 2,210,725 - Rv1967 0.12 -1.7 2,210,725 - Rv1967 0.12 -0.4 2,211,272 - Rv1967 0.65 -0.1 2,211,447 + Rv1967 0.82 +1.7 2,211,447 + Rv1967 0.82 +2.7 2,211,447 + Rv1967 0.82 -0.3 2,211,448 - Rv1967 0.82 -0.6 2,211,483 + Rv1967 0.86 -0.1 2,211,483 + Rv1967 0.86 +0.4 2,211,511 - Rv1967 0.88 +0.0 2,211,511 - Rv1967 0.88 -0.1 2,211,531 + -0.2 2,211,583 - -0.5 2,211,583 - -0.2 2,211,713 + +0.1 2,212,019 + Rv1968 0.32 -0.1 2,212,124 - Rv1968 0.40 +1.3 2,212,544 + Rv1968 0.74 +0.2 2,212,544 + Rv1968 0.74 +0.6 2,212,544 + Rv1968 0.74 +0.0 2,212,545 - Rv1968 0.75 +1.0 2,212,545 - Rv1968 0.75 +0.0 2,213,102 - Rv1969 0.19 -0.7 2,213,102 - Rv1969 0.19 -0.3 2,213,216 + Rv1969 0.28 -0.0 2,213,217 - Rv1969 0.28 -1.1
Or see this region's nucleotide sequence