Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1145

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
1,271,427	+		Rv1144	0.36	-0.4
1,271,428	-		Rv1144	0.36	-0.9
1,271,428	-		Rv1144	0.36	+0.3
1,271,573	-		Rv1144	0.55	-0.2
1,271,643	+		Rv1144	0.65	-0.3
1,271,644	-		Rv1144	0.65	-1.4
1,271,817	-		Rv1144	0.88	-0.5
1,271,827	-		Rv1144	0.89	+0.3
1,271,858	-				+0.1
1,272,093	+				-1.4
1,272,113	-				-0.6
1,272,179	+				-0.3
1,272,180	-				+0.5
1,272,193	-				-0.8
1,272,200	+				-0.3
1,272,200	+				+0.4
1,272,318	+				-0.3
1,272,318	+				-0.6
1,272,319	-				-1.0
1,272,319	-				-0.2
1,272,319	-				+0.4
1,272,319	-				-1.3
1,272,322	+				-0.3
1,272,322	+				+0.6
1,272,323	-				-0.3
1,272,323	-				-0.6
1,272,347	+				+0.1
1,272,347	+				-0.1
1,272,347	+				-0.3
1,272,348	-				-0.6
1,272,348	-				+0.1
1,272,353	-				+1.0
1,272,353	-				-0.3
1,272,361	+				-0.6
1,272,362	-				+0.2
1,272,362	-				+1.3
1,272,723	+		Rv1145	0.33	+0.4
1,272,723	+		Rv1145	0.33	+0.3
1,272,724	-		Rv1145	0.33	+0.0
1,272,922	-		Rv1145	0.55	+0.8
1,273,094	+		Rv1145	0.74	+0.8
1,273,095	-		Rv1145	0.74	+0.0
1,273,136	+		Rv1145	0.78	+0.2
1,273,136	+		Rv1145	0.78	-0.0
1,273,137	-		Rv1145	0.78	-0.5
1,273,168	-		Rv1145	0.82	-0.6
1,273,168	-		Rv1145	0.82	-1.3
1,273,326	-				-0.4
1,273,419	+				+3.9
1,273,419	+				-0.2
1,273,420	-				-0.2
1,273,420	-				-0.2
1,273,675	+		Rv1146	0.23	+0.3
1,273,716	+		Rv1146	0.26	+1.9
1,273,717	-		Rv1146	0.26	-0.4
1,273,769	+		Rv1146	0.29	-0.3
1,273,769	+		Rv1146	0.29	+0.3
1,273,770	-		Rv1146	0.29	-0.1
1,273,770	-		Rv1146	0.29	+0.7
1,273,770	-		Rv1146	0.29	+0.5
1,273,800	+		Rv1146	0.31	-0.0
1,273,801	-		Rv1146	0.32	+1.0
1,274,062	-		Rv1146	0.50	-0.0
1,274,062	-		Rv1146	0.50	-0.5
1,274,068	-		Rv1146	0.50	-0.6
1,274,084	+		Rv1146	0.52	+0.5
1,274,084	+		Rv1146	0.52	+0.1
1,274,084	+		Rv1146	0.52	-0.4
1,274,084	+		Rv1146	0.52	-0.4
1,274,084	+		Rv1146	0.52	-0.1
1,274,084	+		Rv1146	0.52	+0.3
1,274,084	+		Rv1146	0.52	+0.4
1,274,085	-		Rv1146	0.52	-0.3
1,274,085	-		Rv1146	0.52	-0.0
1,274,085	-		Rv1146	0.52	+0.1
1,274,085	-		Rv1146	0.52	+0.1
1,274,085	-		Rv1146	0.52	+0.4
1,274,088	+		Rv1146	0.52	+0.9
1,274,088	+		Rv1146	0.52	-0.1
1,274,088	+		Rv1146	0.52	+0.4
1,274,088	+		Rv1146	0.52	+0.3
1,274,088	+		Rv1146	0.52	-0.1
1,274,089	-		Rv1146	0.52	-0.2
1,274,089	-		Rv1146	0.52	-0.1
1,274,144	-		Rv1146	0.56	-0.0
1,274,152	-		Rv1146	0.56	+0.1
1,274,248	+		Rv1146	0.63	-0.0
1,274,248	+		Rv1146	0.63	+0.9
1,274,249	-		Rv1146	0.63	+0.5
1,274,249	-		Rv1146	0.63	-0.0
1,274,259	+		Rv1146	0.64	-1.5
1,274,259	+		Rv1146	0.64	-0.1
1,274,295	-		Rv1146	0.67	+0.0
1,274,327	+		Rv1146	0.69	+1.0