Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0551c

Experiment: 7H9 with Linezolid 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0549c and Rv0550c overlap by 4 nucleotidesRv0550c and Rv0551c are separated by 191 nucleotidesRv0551c and Rv0552 are separated by 77 nucleotides Rv0549c: Rv0549c - Possible toxin VapC3, at 640,228 to 640,641 Rv0549c Rv0550c: Rv0550c - Possible antitoxin VapB3, at 640,638 to 640,904 Rv0550c Rv0551c: Rv0551c - Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 641,096 to 642,811 Rv0551c Rv0552: Rv0552 - Conserved protein, at 642,889 to 644,493 Rv0552 Position (kb) 641 642 643Strain fitness (log2 ratio) -1 0 1 2at 640.178 kb on + strandat 640.179 kb on - strandat 640.179 kb on - strandat 640.436 kb on + strand, within Rv0549cat 640.437 kb on - strand, within Rv0549cat 640.576 kb on + strand, within Rv0549cat 640.837 kb on + strand, within Rv0550cat 640.838 kb on - strand, within Rv0550cat 641.049 kb on - strandat 641.049 kb on - strandat 641.162 kb on + strandat 641.163 kb on - strandat 641.463 kb on + strand, within Rv0551cat 641.463 kb on + strand, within Rv0551cat 641.463 kb on + strand, within Rv0551cat 641.464 kb on - strand, within Rv0551cat 641.466 kb on + strand, within Rv0551cat 641.466 kb on + strand, within Rv0551cat 641.467 kb on - strand, within Rv0551cat 641.467 kb on - strand, within Rv0551cat 641.712 kb on + strand, within Rv0551cat 641.712 kb on + strand, within Rv0551cat 641.748 kb on + strand, within Rv0551cat 641.821 kb on - strand, within Rv0551cat 642.045 kb on - strand, within Rv0551cat 642.239 kb on + strand, within Rv0551cat 642.239 kb on + strand, within Rv0551cat 642.397 kb on - strand, within Rv0551cat 642.556 kb on - strand, within Rv0551cat 642.565 kb on + strand, within Rv0551cat 642.779 kb on + strandat 642.779 kb on + strandat 642.823 kb on - strandat 642.823 kb on - strandat 643.342 kb on + strand, within Rv0552at 643.411 kb on + strand, within Rv0552at 643.411 kb on + strand, within Rv0552at 643.487 kb on + strand, within Rv0552

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.3 ug/mL
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640,178 + -0.3
640,179 - -0.2
640,179 - -0.5
640,436 + Rv0549c 0.50 +0.7
640,437 - Rv0549c 0.50 +2.1
640,576 + Rv0549c 0.84 +1.8
640,837 + Rv0550c 0.75 +0.2
640,838 - Rv0550c 0.75 -0.1
641,049 - +0.2
641,049 - -0.1
641,162 + +0.0
641,163 - -0.4
641,463 + Rv0551c 0.21 -0.6
641,463 + Rv0551c 0.21 +1.0
641,463 + Rv0551c 0.21 +1.6
641,464 - Rv0551c 0.21 +0.8
641,466 + Rv0551c 0.22 -0.7
641,466 + Rv0551c 0.22 +0.3
641,467 - Rv0551c 0.22 -1.1
641,467 - Rv0551c 0.22 +0.6
641,712 + Rv0551c 0.36 +0.8
641,712 + Rv0551c 0.36 -1.7
641,748 + Rv0551c 0.38 +0.3
641,821 - Rv0551c 0.42 +0.5
642,045 - Rv0551c 0.55 +0.8
642,239 + Rv0551c 0.67 -0.1
642,239 + Rv0551c 0.67 -0.4
642,397 - Rv0551c 0.76 +1.0
642,556 - Rv0551c 0.85 -0.2
642,565 + Rv0551c 0.86 +0.1
642,779 + -0.5
642,779 + +0.9
642,823 - -0.4
642,823 - +1.0
643,342 + Rv0552 0.28 +1.6
643,411 + Rv0552 0.33 -0.7
643,411 + Rv0552 0.33 -0.3
643,487 + Rv0552 0.37 -0.6

Or see this region's nucleotide sequence