Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3235

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
3,610,424	-				-0.5
3,610,451	+				-1.6
3,610,605	+		Rv3234c	0.28	-1.3
3,610,605	+		Rv3234c	0.28	-2.4
3,610,605	+		Rv3234c	0.28	-0.1
3,610,606	-		Rv3234c	0.28	-0.1
3,610,606	-		Rv3234c	0.28	+1.3
3,610,792	+		Rv3234c	0.51	+0.0
3,610,793	-		Rv3234c	0.51	-0.1
3,610,831	+		Rv3234c	0.56	+0.3
3,610,831	+		Rv3234c	0.56	-1.0
3,610,831	+		Rv3234c	0.56	-1.0
3,610,832	-		Rv3234c	0.56	-0.4
3,610,832	-		Rv3234c	0.56	-0.1
3,610,832	-		Rv3234c	0.56	-0.7
3,610,946	-		Rv3234c	0.70	+0.8
3,610,946	-		Rv3234c	0.70	-0.2
3,610,946	-		Rv3234c	0.70	+0.3
3,610,946	-		Rv3234c	0.70	+0.5
3,611,122	+				-1.0
3,611,123	-				-0.3
3,611,123	-				+0.3
3,611,123	-				+0.7
3,611,123	-				+0.4
3,611,123	-				-0.3
3,611,123	-				+0.0
3,611,123	-				+1.7
3,611,152	+				-0.7
3,611,404	+		Rv3235	0.16	-0.7
3,611,529	+		Rv3235	0.36	-0.6
3,611,840	+		Rv3235	0.84	-1.8
3,611,840	+		Rv3235	0.84	-1.9
3,611,840	+		Rv3235	0.84	-0.5
3,611,841	-		Rv3235	0.84	-0.4
3,611,841	-		Rv3235	0.84	-0.1
3,611,841	-		Rv3235	0.84	-3.7
3,611,961	-				+0.7
3,611,971	+				-0.8
3,611,972	-				+0.1
3,612,044	+				-0.1
3,612,044	+				-0.6
3,612,045	-				+1.3
3,612,623	+		Rv3236c	0.57	-0.4
3,612,741	-		Rv3236c	0.68	-0.1