Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2550c

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
2,869,139	+		Rv2548	0.74	+0.0
2,869,140	-		Rv2548	0.74	-1.3
2,869,233	-				-0.0
2,869,702	-				-0.2
2,869,740	-				-0.8
2,869,782	+		Rv2549c	0.14	-0.4
2,869,782	+		Rv2549c	0.14	-1.1
2,869,782	+		Rv2549c	0.14	+0.2
2,869,782	+		Rv2549c	0.14	-1.3
2,869,782	+		Rv2549c	0.14	-0.4
2,869,783	-		Rv2549c	0.14	+0.2
2,869,783	-		Rv2549c	0.14	-0.7
2,869,783	-		Rv2549c	0.14	-0.0
2,869,783	-		Rv2549c	0.14	-0.0
2,869,901	+		Rv2549c	0.44	-0.5
2,869,901	+		Rv2549c	0.44	+0.1
2,869,901	+		Rv2549c	0.44	+1.9
2,869,901	+		Rv2549c	0.44	+0.3
2,870,240	+		Rv2550c	0.49	-0.0
2,870,321	+		Rv2550c	0.82	-0.9
2,870,321	+		Rv2550c	0.82	-0.3
2,870,322	-		Rv2550c	0.83	-2.3
2,870,322	-		Rv2550c	0.83	-2.5
2,870,322	-		Rv2550c	0.83	-0.2
2,870,322	-		Rv2550c	0.83	-0.3
2,870,521	+				+0.2
2,870,550	+				+0.6
2,870,561	+				-0.7
2,871,019	+		Rv2551c	0.58	-2.1
2,871,020	-		Rv2551c	0.58	-0.8
2,871,208	-				+0.4
2,871,208	-				-0.4