Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2326c

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
2,596,875	-				-0.2
2,596,891	-				+0.8
2,597,010	+				+2.2
2,597,010	+				-0.1
2,597,011	-				+0.1
2,597,011	-				-2.4
2,597,021	+				+0.5
2,597,022	-				-0.5
2,597,777	-				-2.0
2,597,962	+				-0.4
2,598,332	-		Rv2326c	0.23	-0.2
2,598,491	+		Rv2326c	0.30	-1.0
2,598,491	+		Rv2326c	0.30	-0.1
2,598,586	-		Rv2326c	0.35	+0.5
2,598,586	-		Rv2326c	0.35	-0.4
2,598,651	-		Rv2326c	0.38	+0.2
2,599,058	-		Rv2326c	0.57	+0.8
2,599,105	+		Rv2326c	0.60	+0.3
2,599,105	+		Rv2326c	0.60	+0.3
2,599,256	-		Rv2326c	0.67	+2.7
2,599,343	+		Rv2326c	0.71	+0.8
2,599,344	-		Rv2326c	0.71	+0.2
2,599,368	-		Rv2326c	0.72	-0.2
2,599,389	-		Rv2326c	0.73	-0.1
2,599,446	+		Rv2326c	0.76	+0.3
2,599,619	+		Rv2326c	0.84	-0.9
2,599,619	+		Rv2326c	0.84	+1.1
2,599,619	+		Rv2326c	0.84	+0.8
2,599,619	+		Rv2326c	0.84	-1.6
2,599,619	+		Rv2326c	0.84	-1.7
2,599,620	-		Rv2326c	0.84	-1.6
2,599,620	-		Rv2326c	0.84	+0.2
2,600,416	-		Rv2327	0.87	-0.3
2,600,478	-				-0.5
2,600,478	-				-0.4
2,600,597	-				+0.9
2,600,673	+				+1.7
2,600,674	-				+0.5
2,600,674	-				-1.2
2,600,674	-				-0.3
2,600,674	-				-0.6
2,600,709	+				-0.4
2,600,709	+				+0.1
2,600,731	-				+1.7
2,600,731	-				-1.6
2,600,815	+				-0.8
2,600,902	+		Rv2328	0.15	-0.5