Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2309c

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
2,580,958	+		Rv2308	0.75	+0.2
2,580,958	+		Rv2308	0.75	-0.6
2,580,959	-		Rv2308	0.75	-0.3
2,581,018	-		Rv2308	0.84	-0.5
2,581,055	+		Rv2308	0.89	-0.5
2,581,055	+		Rv2308	0.89	+0.7
2,581,056	-		Rv2308	0.89	-0.3
2,581,095	-				-0.4
2,581,425	+				+0.5
2,581,425	+				+0.1
2,581,485	+				-0.5
2,581,485	+				-0.8
2,581,486	-				+0.7
2,581,486	-				+0.9
2,581,577	-				-0.3
2,581,666	+				-1.3
2,581,667	-				-0.2
2,581,667	-				+0.6
2,581,740	-				-0.5
2,581,845	-				-0.2
2,582,141	+		Rv2309c	0.65	-2.3
2,582,141	+		Rv2309c	0.65	-1.0
2,582,151	+		Rv2309c	0.68	+0.0
2,582,151	+		Rv2309c	0.68	+0.1
2,582,151	+		Rv2309c	0.68	-0.9
2,582,155	+		Rv2309c	0.68	+0.1
2,582,155	+		Rv2309c	0.68	-1.1
2,582,155	+		Rv2309c	0.68	-0.8
2,582,155	+		Rv2309c	0.68	-0.6
2,582,155	+		Rv2309c	0.68	-0.5
2,582,156	-		Rv2309c	0.69	-0.5
2,582,171	+		Rv2309c	0.72	-1.3
2,582,423	+				+0.4
2,582,424	-				-0.6
2,582,530	+				-1.7
2,582,531	-				-0.5
2,582,531	-				-0.3
2,582,562	+				-0.4
2,582,562	+				+0.5
2,582,563	-				-1.2
2,582,650	+				-0.3
2,582,676	+				-0.2
2,582,676	+				-0.5
2,582,761	+				+0.2
2,582,761	+				-2.4
2,582,761	+				-0.4
2,582,762	-				-0.5
2,582,762	-				+0.2
2,582,856	-				-0.2
2,582,856	-				-0.5
2,582,856	-				-0.4
2,582,903	+				+0.2
2,582,993	+				+0.0
2,582,994	-				-0.4
2,583,003	+				-0.4
2,583,004	-				+0.1
2,583,199	-		Rv2309A	0.53	+0.1
2,583,226	-		Rv2309A	0.63	+0.7
2,583,227	+		Rv2309A	0.63	-0.5
2,583,228	-		Rv2309A	0.64	-0.5
2,583,276	+		Rv2309A	0.80	-2.4
2,583,276	+		Rv2309A	0.80	-0.0
2,583,277	-		Rv2309A	0.81	+1.2
2,583,277	-		Rv2309A	0.81	-0.5
2,583,277	-		Rv2309A	0.81	-0.4