Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2886c

Experiment: 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2885c and Rv2886c overlap by 4 nucleotidesRv2886c and Rv2887 overlap by 2 nucleotidesRv2887 and Rv2888c are separated by 13 nucleotides Rv2885c: Rv2885c - Probable transposase, at 3,194,166 to 3,195,548 Rv2885c Rv2886c: Rv2886c - Probable resolvase, at 3,195,545 to 3,196,432 Rv2886c Rv2887: Rv2887 - Probable transcriptional regulatory protein, at 3,196,431 to 3,196,850 Rv2887 Rv2888c: Rv2888c - Probable amidase AmiC (aminohydrolase), at 3,196,864 to 3,198,285 Rv2888c Position (kb) 3195 3196 3197Strain fitness (log2 ratio) -2 -1 0 1at 3194.622 kb on - strand, within Rv2885cat 3195.047 kb on + strand, within Rv2885cat 3195.048 kb on - strand, within Rv2885cat 3195.152 kb on + strand, within Rv2885cat 3195.217 kb on + strand, within Rv2885cat 3195.218 kb on - strand, within Rv2885cat 3195.218 kb on - strand, within Rv2885cat 3195.550 kb on + strandat 3195.639 kb on - strand, within Rv2886cat 3195.639 kb on - strand, within Rv2886cat 3195.741 kb on - strand, within Rv2886cat 3195.741 kb on - strand, within Rv2886cat 3195.918 kb on - strand, within Rv2886cat 3196.080 kb on + strand, within Rv2886cat 3196.081 kb on - strand, within Rv2886cat 3196.133 kb on - strand, within Rv2886cat 3196.144 kb on + strand, within Rv2886cat 3196.311 kb on + strand, within Rv2886cat 3196.312 kb on - strand, within Rv2886cat 3196.438 kb on + strandat 3196.487 kb on - strand, within Rv2887at 3196.709 kb on + strand, within Rv2887at 3196.849 kb on - strandat 3196.922 kb on + strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3196.923 kb on - strandat 3197.011 kb on + strand, within Rv2888cat 3197.100 kb on + strand, within Rv2888cat 3197.111 kb on + strand, within Rv2888cat 3197.111 kb on + strand, within Rv2888cat 3197.194 kb on + strand, within Rv2888cat 3197.194 kb on + strand, within Rv2888cat 3197.286 kb on + strand, within Rv2888cat 3197.286 kb on + strand, within Rv2888cat 3197.354 kb on + strand, within Rv2888cat 3197.354 kb on + strand, within Rv2888cat 3197.355 kb on - strand, within Rv2888cat 3197.355 kb on - strand, within Rv2888cat 3197.410 kb on + strand, within Rv2888cat 3197.422 kb on + strand, within Rv2888cat 3197.422 kb on + strand, within Rv2888cat 3197.423 kb on - strand, within Rv2888cat 3197.423 kb on - strand, within Rv2888c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
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3,194,622 - Rv2885c 0.33 -0.8
3,195,047 + Rv2885c 0.64 +0.1
3,195,048 - Rv2885c 0.64 -1.0
3,195,152 + Rv2885c 0.71 -0.0
3,195,217 + Rv2885c 0.76 -0.4
3,195,218 - Rv2885c 0.76 -0.2
3,195,218 - Rv2885c 0.76 -0.2
3,195,550 + +0.7
3,195,639 - Rv2886c 0.11 -0.2
3,195,639 - Rv2886c 0.11 -0.6
3,195,741 - Rv2886c 0.22 +0.0
3,195,741 - Rv2886c 0.22 +0.8
3,195,918 - Rv2886c 0.42 +0.0
3,196,080 + Rv2886c 0.60 -2.5
3,196,081 - Rv2886c 0.60 -0.5
3,196,133 - Rv2886c 0.66 -1.0
3,196,144 + Rv2886c 0.67 -0.3
3,196,311 + Rv2886c 0.86 -0.6
3,196,312 - Rv2886c 0.86 -1.1
3,196,438 + -1.8
3,196,487 - Rv2887 0.13 -1.3
3,196,709 + Rv2887 0.66 -1.0
3,196,849 - +0.7
3,196,922 + +0.8
3,196,923 - -0.3
3,196,923 - -0.2
3,196,923 - +0.1
3,196,923 - -0.3
3,197,011 + Rv2888c 0.10 +0.4
3,197,100 + Rv2888c 0.17 +1.2
3,197,111 + Rv2888c 0.17 +1.0
3,197,111 + Rv2888c 0.17 +0.4
3,197,194 + Rv2888c 0.23 +0.0
3,197,194 + Rv2888c 0.23 -0.4
3,197,286 + Rv2888c 0.30 -1.0
3,197,286 + Rv2888c 0.30 +1.2
3,197,354 + Rv2888c 0.34 -0.1
3,197,354 + Rv2888c 0.34 -0.1
3,197,355 - Rv2888c 0.35 +0.2
3,197,355 - Rv2888c 0.35 -2.6
3,197,410 + Rv2888c 0.38 -0.3
3,197,422 + Rv2888c 0.39 +0.1
3,197,422 + Rv2888c 0.39 -0.2
3,197,423 - Rv2888c 0.39 -0.8
3,197,423 - Rv2888c 0.39 -0.3

Or see this region's nucleotide sequence