Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2749

Experiment: 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2748c and Rv2749 overlap by 2 nucleotidesRv2749 and Rv2750 overlap by 4 nucleotidesRv2750 and Rv2751 are separated by 3 nucleotides Rv2748c: Rv2748c - Possible cell division transmembrane protein FtsK, at 3,059,855 to 3,062,506 Rv2748c Rv2749: Rv2749 - Conserved protein, at 3,062,505 to 3,062,819 Rv2749 Rv2750: Rv2750 - Probable dehydrogenase, at 3,062,816 to 3,063,634 Rv2750 Rv2751: Rv2751 - Conserved protein, at 3,063,638 to 3,064,528 Rv2751 Position (kb) 3062 3063Strain fitness (log2 ratio) -1 0 1at 3062.370 kb on - strandat 3062.381 kb on + strandat 3062.382 kb on - strandat 3062.620 kb on - strand, within Rv2749at 3062.693 kb on + strand, within Rv2749at 3063.211 kb on - strand, within Rv2750at 3063.211 kb on - strand, within Rv2750at 3063.427 kb on + strand, within Rv2750at 3063.632 kb on + strandat 3063.810 kb on + strand, within Rv2751at 3063.811 kb on - strand, within Rv2751

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
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3,062,370 - +1.3
3,062,381 + -1.6
3,062,382 - +1.3
3,062,620 - Rv2749 0.37 -1.7
3,062,693 + Rv2749 0.60 -0.0
3,063,211 - Rv2750 0.48 +0.3
3,063,211 - Rv2750 0.48 -0.5
3,063,427 + Rv2750 0.75 +1.3
3,063,632 + -0.3
3,063,810 + Rv2751 0.19 -0.5
3,063,811 - Rv2751 0.19 -1.5

Or see this region's nucleotide sequence