Experiment: 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2332 and Rv2333c overlap by 47 nucleotides Rv2333c and Rv2334 are separated by 474 nucleotides
Rv2332: Rv2332 - Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me), at 2,605,108 to 2,606,754
Rv2332
Rv2333c: Rv2333c - Integral membrane drug efflux protein Stp, at 2,606,708 to 2,608,321
Rv2333c
Rv2334: Rv2334 - Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A), at 2,608,796 to 2,609,728
Rv2334
Position (kb)
2606
2607
2608
2609 Strain fitness (log2 ratio)
-2
-1
0
1 at 2605.718 kb on - strand, within Rv2332 at 2605.718 kb on - strand, within Rv2332 at 2605.779 kb on + strand, within Rv2332 at 2605.860 kb on - strand, within Rv2332 at 2605.867 kb on + strand, within Rv2332 at 2605.867 kb on + strand, within Rv2332 at 2605.868 kb on - strand, within Rv2332 at 2605.868 kb on - strand, within Rv2332 at 2605.868 kb on - strand, within Rv2332 at 2605.868 kb on - strand, within Rv2332 at 2605.880 kb on - strand, within Rv2332 at 2605.935 kb on - strand, within Rv2332 at 2605.936 kb on + strand, within Rv2332 at 2605.982 kb on + strand, within Rv2332 at 2605.982 kb on + strand, within Rv2332 at 2605.983 kb on - strand, within Rv2332 at 2605.983 kb on - strand, within Rv2332 at 2605.983 kb on - strand, within Rv2332 at 2606.153 kb on - strand, within Rv2332 at 2606.236 kb on - strand, within Rv2332 at 2606.236 kb on - strand, within Rv2332 at 2606.449 kb on + strand, within Rv2332 at 2606.450 kb on - strand, within Rv2332 at 2606.529 kb on - strand, within Rv2332 at 2606.747 kb on - strand at 2606.780 kb on - strand at 2606.795 kb on + strand at 2606.795 kb on + strand at 2606.796 kb on - strand at 2607.443 kb on - strand, within Rv2333c at 2607.444 kb on + strand, within Rv2333c at 2607.445 kb on - strand, within Rv2333c at 2607.492 kb on + strand, within Rv2333c at 2607.492 kb on + strand, within Rv2333c at 2607.537 kb on + strand, within Rv2333c at 2607.690 kb on + strand, within Rv2333c at 2607.691 kb on - strand, within Rv2333c at 2607.760 kb on + strand, within Rv2333c at 2607.777 kb on + strand, within Rv2333c at 2607.777 kb on + strand, within Rv2333c at 2607.825 kb on + strand, within Rv2333c at 2607.825 kb on + strand, within Rv2333c at 2607.825 kb on + strand, within Rv2333c at 2607.826 kb on - strand, within Rv2333c at 2607.826 kb on - strand, within Rv2333c at 2607.826 kb on - strand, within Rv2333c at 2607.826 kb on - strand, within Rv2333c at 2607.889 kb on + strand, within Rv2333c at 2608.063 kb on + strand, within Rv2333c at 2608.091 kb on + strand, within Rv2333c at 2608.091 kb on + strand, within Rv2333c at 2608.092 kb on - strand, within Rv2333c at 2608.171 kb on - strand at 2608.335 kb on + strand at 2608.335 kb on + strand at 2608.335 kb on + strand at 2608.335 kb on + strand at 2608.336 kb on - strand at 2608.370 kb on + strand at 2608.370 kb on + strand at 2608.370 kb on + strand at 2608.371 kb on - strand at 2608.485 kb on - strand at 2608.485 kb on - strand at 2608.514 kb on + strand at 2608.516 kb on + strand at 2608.539 kb on + strand at 2608.552 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM remove 2,605,718 - Rv2332 0.37 +0.8 2,605,718 - Rv2332 0.37 +0.2 2,605,779 + Rv2332 0.41 +0.7 2,605,860 - Rv2332 0.46 -0.9 2,605,867 + Rv2332 0.46 -0.1 2,605,867 + Rv2332 0.46 -1.9 2,605,868 - Rv2332 0.46 -1.1 2,605,868 - Rv2332 0.46 -1.0 2,605,868 - Rv2332 0.46 -0.2 2,605,868 - Rv2332 0.46 +0.4 2,605,880 - Rv2332 0.47 -0.8 2,605,935 - Rv2332 0.50 -0.6 2,605,936 + Rv2332 0.50 +0.0 2,605,982 + Rv2332 0.53 +1.4 2,605,982 + Rv2332 0.53 +0.2 2,605,983 - Rv2332 0.53 +0.6 2,605,983 - Rv2332 0.53 -0.6 2,605,983 - Rv2332 0.53 -0.3 2,606,153 - Rv2332 0.63 -0.7 2,606,236 - Rv2332 0.68 -0.7 2,606,236 - Rv2332 0.68 -0.2 2,606,449 + Rv2332 0.81 -0.2 2,606,450 - Rv2332 0.81 +0.1 2,606,529 - Rv2332 0.86 -0.4 2,606,747 - -0.1 2,606,780 - -1.0 2,606,795 + -0.4 2,606,795 + -1.1 2,606,796 - -0.5 2,607,443 - Rv2333c 0.46 -0.7 2,607,444 + Rv2333c 0.46 -0.6 2,607,445 - Rv2333c 0.46 +0.3 2,607,492 + Rv2333c 0.49 -0.2 2,607,492 + Rv2333c 0.49 -0.2 2,607,537 + Rv2333c 0.51 -0.7 2,607,690 + Rv2333c 0.61 +0.3 2,607,691 - Rv2333c 0.61 +0.5 2,607,760 + Rv2333c 0.65 -0.4 2,607,777 + Rv2333c 0.66 +0.3 2,607,777 + Rv2333c 0.66 -0.8 2,607,825 + Rv2333c 0.69 -0.2 2,607,825 + Rv2333c 0.69 -1.6 2,607,825 + Rv2333c 0.69 -0.9 2,607,826 - Rv2333c 0.69 -0.8 2,607,826 - Rv2333c 0.69 -0.5 2,607,826 - Rv2333c 0.69 -0.5 2,607,826 - Rv2333c 0.69 -1.5 2,607,889 + Rv2333c 0.73 -1.2 2,608,063 + Rv2333c 0.84 +0.1 2,608,091 + Rv2333c 0.86 -0.8 2,608,091 + Rv2333c 0.86 -0.1 2,608,092 - Rv2333c 0.86 -0.6 2,608,171 - +0.6 2,608,335 + -0.4 2,608,335 + -1.2 2,608,335 + +0.3 2,608,335 + -0.1 2,608,336 - -1.4 2,608,370 + -0.3 2,608,370 + -1.8 2,608,370 + -1.0 2,608,371 - +0.1 2,608,485 - -1.0 2,608,485 - +0.5 2,608,514 + +0.2 2,608,516 + -0.4 2,608,539 + -0.1 2,608,552 + +0.3
Or see this region's nucleotide sequence