Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1100

Experiment: 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1099c and Rv1100 overlap by 2 nucleotidesRv1100 and Rv1101c are separated by 6 nucleotides Rv1099c: Rv1099c - Fructose 1,6-bisphosphatase GlpX, at 1,227,596 to 1,228,684 Rv1099c Rv1100: Rv1100 - Conserved protein, at 1,228,683 to 1,229,384 Rv1100 Rv1101c: Rv1101c - Conserved membrane protein, at 1,229,391 to 1,230,548 Rv1101c Position (kb) 1228 1229 1230Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1227.867 kb on - strand, within Rv1099cat 1228.243 kb on - strand, within Rv1099cat 1228.914 kb on + strand, within Rv1100at 1228.915 kb on - strand, within Rv1100at 1228.915 kb on - strand, within Rv1100at 1229.110 kb on - strand, within Rv1100at 1229.110 kb on - strand, within Rv1100at 1229.175 kb on + strand, within Rv1100at 1229.503 kb on + strandat 1229.504 kb on - strandat 1229.515 kb on + strand, within Rv1101cat 1229.567 kb on + strand, within Rv1101cat 1229.567 kb on + strand, within Rv1101cat 1229.591 kb on + strand, within Rv1101cat 1229.682 kb on - strand, within Rv1101cat 1229.682 kb on - strand, within Rv1101cat 1229.851 kb on + strand, within Rv1101cat 1229.851 kb on + strand, within Rv1101cat 1229.945 kb on - strand, within Rv1101cat 1229.945 kb on - strand, within Rv1101cat 1229.997 kb on + strand, within Rv1101cat 1229.997 kb on + strand, within Rv1101cat 1229.997 kb on + strand, within Rv1101cat 1229.998 kb on - strand, within Rv1101cat 1230.034 kb on + strand, within Rv1101cat 1230.034 kb on + strand, within Rv1101cat 1230.035 kb on - strand, within Rv1101cat 1230.035 kb on - strand, within Rv1101cat 1230.035 kb on - strand, within Rv1101cat 1230.035 kb on - strand, within Rv1101cat 1230.161 kb on + strand, within Rv1101cat 1230.162 kb on - strand, within Rv1101c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
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1,227,867 - Rv1099c 0.25 -2.6
1,228,243 - Rv1099c 0.59 +0.6
1,228,914 + Rv1100 0.33 -1.0
1,228,915 - Rv1100 0.33 -1.3
1,228,915 - Rv1100 0.33 -0.7
1,229,110 - Rv1100 0.61 -1.2
1,229,110 - Rv1100 0.61 -1.3
1,229,175 + Rv1100 0.70 -0.8
1,229,503 + -0.0
1,229,504 - +0.1
1,229,515 + Rv1101c 0.11 -0.9
1,229,567 + Rv1101c 0.15 -0.5
1,229,567 + Rv1101c 0.15 -0.8
1,229,591 + Rv1101c 0.17 -0.2
1,229,682 - Rv1101c 0.25 -0.6
1,229,682 - Rv1101c 0.25 -0.5
1,229,851 + Rv1101c 0.40 -0.6
1,229,851 + Rv1101c 0.40 +2.8
1,229,945 - Rv1101c 0.48 -0.0
1,229,945 - Rv1101c 0.48 -0.5
1,229,997 + Rv1101c 0.52 -0.2
1,229,997 + Rv1101c 0.52 -1.8
1,229,997 + Rv1101c 0.52 +1.4
1,229,998 - Rv1101c 0.52 +0.4
1,230,034 + Rv1101c 0.56 -0.1
1,230,034 + Rv1101c 0.56 -0.4
1,230,035 - Rv1101c 0.56 -0.5
1,230,035 - Rv1101c 0.56 -0.4
1,230,035 - Rv1101c 0.56 -0.2
1,230,035 - Rv1101c 0.56 -0.2
1,230,161 + Rv1101c 0.66 +0.2
1,230,162 - Rv1101c 0.67 +1.4

Or see this region's nucleotide sequence