Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0020c

Experiment: 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0018c and Rv0019c are separated by 88 nucleotidesRv0019c and Rv0020c are separated by 123 nucleotidesRv0020c and GFF23 are separated by 199 nucleotidesGFF23 and Rv0021c are separated by 186 nucleotides Rv0018c: Rv0018c - Phosphoserine/threonine phosphatase PstP, at 21,637 to 23,181 Rv0018c Rv0019c: Rv0019c - Conserved protein with FHA domain, FhaB, at 23,270 to 23,737 Rv0019c Rv0020c: Rv0020c - Conserved protein with FHA domain, FhaA, at 23,861 to 25,444 Rv0020c GFF23 - tRNA-Leu, at 25,644 to 25,726 GFF23 Rv0021c: Rv0021c - Conserved hypothetical protein, at 25,913 to 26,881 Rv0021c Position (kb) 23 24 25 26Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 23.382 kb on - strand, within Rv0019cat 23.382 kb on - strand, within Rv0019cat 23.443 kb on - strand, within Rv0019cat 23.443 kb on - strand, within Rv0019cat 23.513 kb on - strand, within Rv0019cat 23.641 kb on - strand, within Rv0019cat 23.856 kb on + strandat 23.857 kb on - strandat 24.987 kb on - strand, within Rv0020cat 24.987 kb on - strand, within Rv0020cat 25.143 kb on + strand, within Rv0020cat 25.170 kb on + strand, within Rv0020cat 25.171 kb on - strand, within Rv0020cat 25.171 kb on - strand, within Rv0020cat 25.260 kb on + strand, within Rv0020cat 25.261 kb on - strand, within Rv0020cat 25.261 kb on - strand, within Rv0020cat 25.261 kb on - strand, within Rv0020cat 25.261 kb on - strand, within Rv0020cat 25.505 kb on + strandat 25.505 kb on + strandat 25.506 kb on - strandat 25.506 kb on - strandat 25.616 kb on + strandat 25.616 kb on + strandat 25.616 kb on + strandat 25.616 kb on + strandat 25.616 kb on + strandat 25.617 kb on - strandat 25.617 kb on - strandat 25.624 kb on + strandat 25.730 kb on + strandat 25.730 kb on + strandat 25.731 kb on - strandat 25.796 kb on + strandat 25.907 kb on - strandat 25.914 kb on + strandat 25.915 kb on - strandat 25.915 kb on - strandat 25.915 kb on - strandat 25.915 kb on - strandat 25.960 kb on + strandat 26.040 kb on + strand, within Rv0021cat 26.040 kb on + strand, within Rv0021cat 26.040 kb on + strand, within Rv0021cat 26.041 kb on - strand, within Rv0021cat 26.041 kb on - strand, within Rv0021cat 26.068 kb on - strand, within Rv0021cat 26.141 kb on + strand, within Rv0021cat 26.141 kb on + strand, within Rv0021cat 26.142 kb on - strand, within Rv0021cat 26.193 kb on + strand, within Rv0021cat 26.193 kb on + strand, within Rv0021cat 26.197 kb on + strand, within Rv0021cat 26.197 kb on + strand, within Rv0021cat 26.197 kb on + strand, within Rv0021cat 26.197 kb on + strand, within Rv0021cat 26.197 kb on + strand, within Rv0021cat 26.198 kb on - strand, within Rv0021cat 26.291 kb on - strand, within Rv0021c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Malondialdehyde tetrabutylammonium salt 0.96 mM
remove
23,382 - Rv0019c 0.24 +0.9
23,382 - Rv0019c 0.24 -1.0
23,443 - Rv0019c 0.37 +0.9
23,443 - Rv0019c 0.37 -1.8
23,513 - Rv0019c 0.52 -2.1
23,641 - Rv0019c 0.79 -1.7
23,856 + -1.8
23,857 - +1.1
24,987 - Rv0020c 0.71 -3.1
24,987 - Rv0020c 0.71 -2.0
25,143 + Rv0020c 0.81 -1.7
25,170 + Rv0020c 0.83 -2.3
25,171 - Rv0020c 0.83 -1.8
25,171 - Rv0020c 0.83 -0.4
25,260 + Rv0020c 0.88 -1.1
25,261 - Rv0020c 0.88 -1.2
25,261 - Rv0020c 0.88 -0.9
25,261 - Rv0020c 0.88 -0.0
25,261 - Rv0020c 0.88 +0.9
25,505 + -1.7
25,505 + -1.7
25,506 - -0.2
25,506 - -0.3
25,616 + -0.8
25,616 + -1.1
25,616 + -0.3
25,616 + -1.5
25,616 + -0.4
25,617 - -0.9
25,617 - +0.8
25,624 + +0.3
25,730 + -1.0
25,730 + +0.4
25,731 - +1.0
25,796 + +1.2
25,907 - -1.1
25,914 + -0.4
25,915 - -0.6
25,915 - -0.7
25,915 - +1.9
25,915 - -0.0
25,960 + -1.0
26,040 + Rv0021c 0.13 -0.4
26,040 + Rv0021c 0.13 -0.2
26,040 + Rv0021c 0.13 +2.9
26,041 - Rv0021c 0.13 +0.0
26,041 - Rv0021c 0.13 -0.4
26,068 - Rv0021c 0.16 -0.6
26,141 + Rv0021c 0.24 +0.1
26,141 + Rv0021c 0.24 +0.2
26,142 - Rv0021c 0.24 +0.9
26,193 + Rv0021c 0.29 -1.4
26,193 + Rv0021c 0.29 -0.5
26,197 + Rv0021c 0.29 -1.4
26,197 + Rv0021c 0.29 +0.1
26,197 + Rv0021c 0.29 -0.1
26,197 + Rv0021c 0.29 -0.4
26,197 + Rv0021c 0.29 -1.0
26,198 - Rv0021c 0.29 -0.3
26,291 - Rv0021c 0.39 -0.2

Or see this region's nucleotide sequence