Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1285

Experiment: 7H9 with Dodecyl Sulfate 0.02 vol%

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1283c and Rv1284 are separated by 206 nucleotidesRv1284 and Rv1285 are separated by 93 nucleotidesRv1285 and Rv1286 overlap by 1 nucleotides Rv1283c: Rv1283c - Probable oligopeptide-transport integral membrane protein ABC transporter OppB, at 1,436,140 to 1,437,117 Rv1283c Rv1284: Rv1284 - Beta-carbonic anhydrase, at 1,437,324 to 1,437,815 Rv1284 Rv1285: Rv1285 - Probable sulfate adenylyltransferase subunit 2 CysD, at 1,437,909 to 1,438,907 Rv1285 Rv1286: Rv1286 - Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + adenylylsulfate kinase, at 1,438,907 to 1,440,751 Rv1286 Position (kb) 1437 1438 1439Strain fitness (log2 ratio) -2 -1 0 1 2at 1437.048 kb on - strandat 1437.084 kb on - strandat 1437.084 kb on - strandat 1437.107 kb on + strandat 1437.342 kb on + strandat 1437.342 kb on + strandat 1437.342 kb on + strandat 1437.681 kb on + strand, within Rv1284at 1437.834 kb on + strandat 1437.907 kb on - strandat 1438.624 kb on - strand, within Rv1285at 1439.133 kb on - strand, within Rv1286at 1439.189 kb on + strand, within Rv1286at 1439.792 kb on - strand, within Rv1286at 1439.906 kb on + strand, within Rv1286at 1439.906 kb on + strand, within Rv1286

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Dodecyl Sulfate 0.02 vol%
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1,437,048 - +0.2
1,437,084 - -1.6
1,437,084 - +0.3
1,437,107 + -0.2
1,437,342 + -0.1
1,437,342 + +0.7
1,437,342 + +0.5
1,437,681 + Rv1284 0.73 -1.7
1,437,834 + +0.2
1,437,907 - +0.5
1,438,624 - Rv1285 0.72 +2.7
1,439,133 - Rv1286 0.12 +2.7
1,439,189 + Rv1286 0.15 +0.1
1,439,792 - Rv1286 0.48 +0.4
1,439,906 + Rv1286 0.54 -2.1
1,439,906 + Rv1286 0.54 +0.6

Or see this region's nucleotide sequence