Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2673

Experiment: 7H9 with Hydrogen peroxide 3.97 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2672 and Rv2673 are separated by 22 nucleotidesRv2673 and Rv2674 are separated by 113 nucleotidesRv2674 and Rv2675c are separated by 67 nucleotides Rv2672: Rv2672 - Possible secreted protease, at 2,987,682 to 2,989,268 Rv2672 Rv2673: Rv2673 - Possible arabinofuranosyltransferase AftC, at 2,989,291 to 2,990,592 Rv2673 Rv2674: Rv2674 - Probable peptide methionine sulfoxide reductase MsrB (protein-methionine-R-oxide reductase) (peptide met(O) reductase), at 2,990,706 to 2,991,116 Rv2674 Rv2675c: Rv2675c - Conserved hypothetical protein, at 2,991,184 to 2,991,936 Rv2675c Position (kb) 2989 2990 2991Strain fitness (log2 ratio) -2 -1 0 1 2at 2988.846 kb on - strand, within Rv2672at 2989.163 kb on + strandat 2989.164 kb on - strandat 2989.164 kb on - strandat 2989.164 kb on - strandat 2989.218 kb on + strandat 2989.254 kb on + strandat 2989.254 kb on + strandat 2989.255 kb on - strandat 2989.255 kb on - strandat 2989.269 kb on + strandat 2989.295 kb on - strandat 2989.295 kb on - strandat 2989.337 kb on + strandat 2990.639 kb on + strandat 2990.640 kb on - strandat 2990.694 kb on + strandat 2990.694 kb on + strandat 2990.694 kb on + strandat 2990.723 kb on - strandat 2990.817 kb on + strand, within Rv2674at 2990.844 kb on + strand, within Rv2674at 2990.845 kb on - strand, within Rv2674at 2990.845 kb on - strand, within Rv2674at 2991.045 kb on + strand, within Rv2674at 2991.069 kb on + strand, within Rv2674at 2991.069 kb on + strand, within Rv2674at 2991.070 kb on - strand, within Rv2674at 2991.227 kb on - strandat 2991.227 kb on - strandat 2991.227 kb on - strandat 2991.252 kb on + strandat 2991.253 kb on - strandat 2991.298 kb on - strand, within Rv2675cat 2991.326 kb on - strand, within Rv2675cat 2991.353 kb on + strand, within Rv2675cat 2991.371 kb on + strand, within Rv2675cat 2991.372 kb on - strand, within Rv2675cat 2991.479 kb on + strand, within Rv2675cat 2991.479 kb on + strand, within Rv2675cat 2991.525 kb on - strand, within Rv2675cat 2991.563 kb on + strand, within Rv2675cat 2991.563 kb on + strand, within Rv2675cat 2991.564 kb on - strand, within Rv2675cat 2991.564 kb on - strand, within Rv2675c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Hydrogen peroxide 3.97 mM
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2,988,846 - Rv2672 0.73 +0.8
2,989,163 + -0.9
2,989,164 - -0.1
2,989,164 - -1.4
2,989,164 - -0.2
2,989,218 + +0.7
2,989,254 + -0.9
2,989,254 + -0.2
2,989,255 - +0.1
2,989,255 - -0.7
2,989,269 + -0.2
2,989,295 - +0.7
2,989,295 - +0.3
2,989,337 + +0.0
2,990,639 + +0.5
2,990,640 - +1.8
2,990,694 + +0.8
2,990,694 + -0.3
2,990,694 + +0.2
2,990,723 - -0.7
2,990,817 + Rv2674 0.27 +0.0
2,990,844 + Rv2674 0.34 -1.0
2,990,845 - Rv2674 0.34 -0.0
2,990,845 - Rv2674 0.34 -0.0
2,991,045 + Rv2674 0.82 +0.1
2,991,069 + Rv2674 0.88 -0.5
2,991,069 + Rv2674 0.88 -0.6
2,991,070 - Rv2674 0.89 +0.1
2,991,227 - +0.4
2,991,227 - -1.1
2,991,227 - +1.6
2,991,252 + -0.4
2,991,253 - -0.1
2,991,298 - Rv2675c 0.15 -0.2
2,991,326 - Rv2675c 0.19 +1.8
2,991,353 + Rv2675c 0.22 -2.4
2,991,371 + Rv2675c 0.25 -0.7
2,991,372 - Rv2675c 0.25 +0.5
2,991,479 + Rv2675c 0.39 -1.5
2,991,479 + Rv2675c 0.39 -0.2
2,991,525 - Rv2675c 0.45 -1.1
2,991,563 + Rv2675c 0.50 -0.7
2,991,563 + Rv2675c 0.50 +0.7
2,991,564 - Rv2675c 0.50 +0.3
2,991,564 - Rv2675c 0.50 +0.1

Or see this region's nucleotide sequence