Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1067c

Experiment: 7H9 with Menadione 0.005 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1065 and Rv1066 overlap by 4 nucleotidesRv1066 and Rv1067c are separated by 27 nucleotidesRv1067c and Rv1068c are separated by 332 nucleotides Rv1065: Rv1065 - Conserved hypothetical protein, at 1,187,435 to 1,188,001 Rv1065 Rv1066: Rv1066 - Conserved hypothetical protein, at 1,187,998 to 1,188,393 Rv1066 Rv1067c: Rv1067c - PE-PGRS family protein PE_PGRS19, at 1,188,421 to 1,190,424 Rv1067c Rv1068c: Rv1068c - PE-PGRS family protein PE_PGRS20, at 1,190,757 to 1,192,148 Rv1068c Position (kb) 1188 1189 1190 1191Strain fitness (log2 ratio) -2 -1 0 1 2at 1187.440 kb on + strandat 1187.441 kb on - strandat 1187.603 kb on + strand, within Rv1065at 1187.603 kb on + strand, within Rv1065at 1187.603 kb on + strand, within Rv1065at 1187.635 kb on + strand, within Rv1065at 1187.636 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065at 1187.648 kb on - strand, within Rv1065at 1187.897 kb on + strand, within Rv1065at 1187.928 kb on - strand, within Rv1065at 1188.392 kb on - strandat 1188.392 kb on - strandat 1188.392 kb on - strandat 1189.090 kb on + strand, within Rv1067cat 1189.091 kb on - strand, within Rv1067cat 1189.160 kb on + strand, within Rv1067cat 1189.161 kb on - strand, within Rv1067cat 1189.221 kb on + strand, within Rv1067cat 1190.165 kb on + strand, within Rv1067cat 1190.166 kb on - strand, within Rv1067cat 1190.240 kb on + strandat 1190.241 kb on - strandat 1190.241 kb on - strandat 1190.694 kb on - strandat 1190.704 kb on - strandat 1190.725 kb on + strandat 1190.726 kb on - strandat 1190.759 kb on - strandat 1191.243 kb on - strand, within Rv1068c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Menadione 0.005 mM
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1,187,440 + +1.2
1,187,441 - -0.2
1,187,603 + Rv1065 0.30 +1.7
1,187,603 + Rv1065 0.30 +0.2
1,187,603 + Rv1065 0.30 +0.9
1,187,635 + Rv1065 0.35 -0.1
1,187,636 - Rv1065 0.35 -0.0
1,187,648 - Rv1065 0.38 +0.6
1,187,648 - Rv1065 0.38 +0.0
1,187,648 - Rv1065 0.38 -1.5
1,187,897 + Rv1065 0.81 -0.2
1,187,928 - Rv1065 0.87 -0.2
1,188,392 - -0.1
1,188,392 - +0.2
1,188,392 - -0.5
1,189,090 + Rv1067c 0.33 +2.7
1,189,091 - Rv1067c 0.33 +0.4
1,189,160 + Rv1067c 0.37 -0.2
1,189,161 - Rv1067c 0.37 +0.4
1,189,221 + Rv1067c 0.40 +1.0
1,190,165 + Rv1067c 0.87 +0.7
1,190,166 - Rv1067c 0.87 +0.8
1,190,240 + -0.6
1,190,241 - +0.0
1,190,241 - +0.4
1,190,694 - -1.0
1,190,704 - -1.8
1,190,725 + -0.4
1,190,726 - +1.3
1,190,759 - -0.1
1,191,243 - Rv1068c 0.35 +0.8

Or see this region's nucleotide sequence