Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1731

Experiment: 7H9 with Plumbagin 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1730c and Rv1731 are separated by 431 nucleotidesRv1731 and Rv1732c are separated by 9 nucleotidesRv1732c and Rv1733c are separated by 63 nucleotides Rv1730c: Rv1730c - Possible penicillin-binding protein, at 1,955,692 to 1,957,245 Rv1730c Rv1731: Rv1731 - Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2, at 1,957,677 to 1,959,233 Rv1731 Rv1732c: Rv1732c - Conserved protein, at 1,959,243 to 1,959,791 Rv1732c Rv1733c: Rv1733c - Probable conserved transmembrane protein, at 1,959,855 to 1,960,487 Rv1733c Position (kb) 1957 1958 1959 1960Strain fitness (log2 ratio) -1 0 1at 1956.693 kb on - strand, within Rv1730cat 1956.986 kb on + strand, within Rv1730cat 1957.370 kb on - strandat 1957.631 kb on + strandat 1957.676 kb on + strandat 1958.025 kb on + strand, within Rv1731at 1958.063 kb on + strand, within Rv1731at 1958.109 kb on + strand, within Rv1731at 1958.109 kb on + strand, within Rv1731at 1958.151 kb on + strand, within Rv1731at 1958.152 kb on - strand, within Rv1731at 1958.238 kb on + strand, within Rv1731at 1958.269 kb on - strand, within Rv1731at 1958.356 kb on - strand, within Rv1731at 1958.559 kb on + strand, within Rv1731at 1958.559 kb on + strand, within Rv1731at 1958.661 kb on - strand, within Rv1731at 1958.860 kb on - strand, within Rv1731at 1959.007 kb on - strand, within Rv1731at 1959.191 kb on - strandat 1959.479 kb on - strand, within Rv1732cat 1959.484 kb on + strand, within Rv1732cat 1959.647 kb on - strand, within Rv1732cat 1959.803 kb on + strandat 1959.804 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Plumbagin 0.01 mM
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1,956,693 - Rv1730c 0.64 -0.1
1,956,986 + Rv1730c 0.83 +0.4
1,957,370 - -0.7
1,957,631 + -0.3
1,957,676 + -0.2
1,958,025 + Rv1731 0.22 +0.4
1,958,063 + Rv1731 0.25 -0.1
1,958,109 + Rv1731 0.28 +0.9
1,958,109 + Rv1731 0.28 +0.7
1,958,151 + Rv1731 0.30 -0.1
1,958,152 - Rv1731 0.31 +0.6
1,958,238 + Rv1731 0.36 -0.2
1,958,269 - Rv1731 0.38 +0.2
1,958,356 - Rv1731 0.44 +0.6
1,958,559 + Rv1731 0.57 -0.2
1,958,559 + Rv1731 0.57 -0.2
1,958,661 - Rv1731 0.63 -0.2
1,958,860 - Rv1731 0.76 +0.1
1,959,007 - Rv1731 0.85 +0.0
1,959,191 - +0.7
1,959,479 - Rv1732c 0.43 -0.4
1,959,484 + Rv1732c 0.44 +0.8
1,959,647 - Rv1732c 0.74 -0.2
1,959,803 + -0.5
1,959,804 - +0.5

Or see this region's nucleotide sequence