Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1888c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1887 and Rv1888c are separated by 118 nucleotidesRv1888c and Rv1888A are separated by 364 nucleotidesRv1888A and Rv1889c are separated by 43 nucleotidesRv1889c and Rv1890c are separated by 58 nucleotides Rv1887: Rv1887 - Hypothetical protein, at 2,136,258 to 2,137,400 Rv1887 Rv1888c: Rv1888c - Possible transmembrane protein, at 2,137,519 to 2,138,079 Rv1888c Rv1888A: Rv1888A - Conserved hypothetical protein, at 2,138,444 to 2,138,617 Rv1888A Rv1889c: Rv1889c - Conserved hypothetical protein, at 2,138,661 to 2,139,017 Rv1889c Rv1890c: Rv1890c - Hypothetical protein, at 2,139,076 to 2,139,687 Rv1890c Position (kb) 2137 2138 2139Strain fitness (log2 ratio) -2 -1 0 1 2at 2136.520 kb on + strand, within Rv1887at 2136.572 kb on - strand, within Rv1887at 2136.950 kb on - strand, within Rv1887at 2137.002 kb on + strand, within Rv1887at 2137.139 kb on + strand, within Rv1887at 2137.360 kb on + strandat 2137.361 kb on - strandat 2137.361 kb on - strandat 2137.372 kb on - strandat 2137.491 kb on + strandat 2137.492 kb on - strandat 2137.492 kb on - strandat 2137.529 kb on + strandat 2137.529 kb on + strandat 2137.530 kb on - strandat 2137.530 kb on - strandat 2137.530 kb on - strandat 2137.530 kb on - strandat 2137.530 kb on - strandat 2137.530 kb on - strandat 2137.531 kb on + strandat 2137.531 kb on + strandat 2137.532 kb on - strandat 2137.537 kb on + strandat 2137.613 kb on - strand, within Rv1888cat 2137.685 kb on + strand, within Rv1888cat 2137.685 kb on + strand, within Rv1888cat 2137.686 kb on - strand, within Rv1888cat 2137.696 kb on - strand, within Rv1888cat 2137.702 kb on + strand, within Rv1888cat 2137.702 kb on + strand, within Rv1888cat 2137.713 kb on + strand, within Rv1888cat 2137.713 kb on + strand, within Rv1888cat 2137.749 kb on - strand, within Rv1888cat 2137.773 kb on - strand, within Rv1888cat 2137.835 kb on + strand, within Rv1888cat 2137.835 kb on + strand, within Rv1888cat 2137.899 kb on - strand, within Rv1888cat 2137.899 kb on - strand, within Rv1888cat 2137.899 kb on - strand, within Rv1888cat 2137.980 kb on - strand, within Rv1888cat 2138.008 kb on + strand, within Rv1888cat 2138.095 kb on + strandat 2138.095 kb on + strandat 2138.096 kb on - strandat 2138.096 kb on - strandat 2138.096 kb on - strandat 2138.175 kb on + strandat 2138.176 kb on - strandat 2138.202 kb on + strandat 2138.215 kb on + strandat 2138.215 kb on + strandat 2138.250 kb on - strandat 2138.349 kb on + strandat 2138.446 kb on - strandat 2138.446 kb on - strandat 2138.979 kb on - strand, within Rv1889cat 2138.979 kb on - strand, within Rv1889cat 2139.046 kb on + strandat 2139.046 kb on + strandat 2139.046 kb on + strandat 2139.047 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,136,520 + Rv1887 0.23 +0.3
2,136,572 - Rv1887 0.27 -0.7
2,136,950 - Rv1887 0.61 -0.3
2,137,002 + Rv1887 0.65 -0.7
2,137,139 + Rv1887 0.77 -0.6
2,137,360 + -0.4
2,137,361 - +0.2
2,137,361 - +1.0
2,137,372 - +0.3
2,137,491 + +0.0
2,137,492 - -0.1
2,137,492 - +1.2
2,137,529 + +0.4
2,137,529 + +0.3
2,137,530 - +0.2
2,137,530 - -2.0
2,137,530 - +0.5
2,137,530 - +0.3
2,137,530 - +0.3
2,137,530 - -0.6
2,137,531 + +0.1
2,137,531 + -0.5
2,137,532 - -0.7
2,137,537 + -1.1
2,137,613 - Rv1888c 0.17 -0.3
2,137,685 + Rv1888c 0.30 +0.6
2,137,685 + Rv1888c 0.30 -0.4
2,137,686 - Rv1888c 0.30 +0.6
2,137,696 - Rv1888c 0.32 -0.1
2,137,702 + Rv1888c 0.33 +0.1
2,137,702 + Rv1888c 0.33 +0.1
2,137,713 + Rv1888c 0.35 -0.3
2,137,713 + Rv1888c 0.35 +0.2
2,137,749 - Rv1888c 0.41 +0.8
2,137,773 - Rv1888c 0.45 +0.3
2,137,835 + Rv1888c 0.56 -0.5
2,137,835 + Rv1888c 0.56 -0.6
2,137,899 - Rv1888c 0.68 +1.0
2,137,899 - Rv1888c 0.68 -0.2
2,137,899 - Rv1888c 0.68 +0.5
2,137,980 - Rv1888c 0.82 -0.1
2,138,008 + Rv1888c 0.87 +0.7
2,138,095 + -2.2
2,138,095 + -0.9
2,138,096 - +1.2
2,138,096 - +0.6
2,138,096 - +0.2
2,138,175 + +0.0
2,138,176 - -0.3
2,138,202 + -1.4
2,138,215 + -0.4
2,138,215 + -0.5
2,138,250 - +0.1
2,138,349 + +0.7
2,138,446 - -0.2
2,138,446 - -0.7
2,138,979 - Rv1889c 0.89 -0.6
2,138,979 - Rv1889c 0.89 +2.6
2,139,046 + +0.2
2,139,046 + -0.8
2,139,046 + -0.5
2,139,047 - +0.6

Or see this region's nucleotide sequence