Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2579

Experiment: 7H9 with Antimycin A 0.0186 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2578c and Rv2579 are separated by 107 nucleotidesRv2579 and Rv2580c are separated by 279 nucleotides Rv2578c: Rv2578c - Conserved hypothetical protein, at 2,902,509 to 2,903,531 Rv2578c Rv2579: Rv2579 - Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase), at 2,903,639 to 2,904,541 Rv2579 Rv2580c: Rv2580c - Probable histidyl-tRNA synthetase HisS (histidine--tRNA ligase) (HISRS) (histidine--translase), at 2,904,821 to 2,906,092 Rv2580c Position (kb) 2903 2904 2905Strain fitness (log2 ratio) -1 0 1at 2902.645 kb on - strand, within Rv2578cat 2902.648 kb on + strand, within Rv2578cat 2902.648 kb on + strand, within Rv2578cat 2902.648 kb on + strand, within Rv2578cat 2903.300 kb on - strand, within Rv2578cat 2903.531 kb on + strandat 2903.601 kb on + strandat 2903.601 kb on + strandat 2903.601 kb on + strandat 2903.602 kb on - strandat 2903.602 kb on - strandat 2903.639 kb on - strandat 2903.678 kb on + strandat 2903.683 kb on - strandat 2903.683 kb on - strandat 2903.708 kb on + strandat 2903.708 kb on + strandat 2903.709 kb on - strandat 2903.709 kb on - strandat 2903.768 kb on + strand, within Rv2579at 2903.768 kb on + strand, within Rv2579at 2903.769 kb on - strand, within Rv2579at 2903.769 kb on - strand, within Rv2579at 2903.769 kb on - strand, within Rv2579at 2903.880 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.882 kb on - strand, within Rv2579at 2903.885 kb on + strand, within Rv2579at 2903.886 kb on - strand, within Rv2579at 2903.886 kb on - strand, within Rv2579at 2903.950 kb on - strand, within Rv2579

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Antimycin A 0.0186 mM
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2,902,645 - Rv2578c 0.13 -0.3
2,902,648 + Rv2578c 0.14 -0.8
2,902,648 + Rv2578c 0.14 +0.4
2,902,648 + Rv2578c 0.14 +0.5
2,903,300 - Rv2578c 0.77 -1.0
2,903,531 + -0.9
2,903,601 + -0.0
2,903,601 + -0.1
2,903,601 + -0.1
2,903,602 - +0.8
2,903,602 - +0.1
2,903,639 - -0.0
2,903,678 + -0.2
2,903,683 - -0.4
2,903,683 - -0.2
2,903,708 + -1.0
2,903,708 + -0.4
2,903,709 - -0.9
2,903,709 - -0.1
2,903,768 + Rv2579 0.14 +0.9
2,903,768 + Rv2579 0.14 -0.5
2,903,769 - Rv2579 0.14 +0.9
2,903,769 - Rv2579 0.14 +0.5
2,903,769 - Rv2579 0.14 -0.7
2,903,880 - Rv2579 0.27 -1.3
2,903,882 - Rv2579 0.27 -0.9
2,903,882 - Rv2579 0.27 +0.4
2,903,882 - Rv2579 0.27 +0.1
2,903,885 + Rv2579 0.27 -1.4
2,903,886 - Rv2579 0.27 -1.2
2,903,886 - Rv2579 0.27 -0.2
2,903,950 - Rv2579 0.34 -1.0

Or see this region's nucleotide sequence