Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2326c

Experiment: 7H9 with Antimycin A 0.0186 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2325c and Rv2326c overlap by 4 nucleotidesRv2326c and Rv2327 are separated by 40 nucleotidesRv2327 and Rv2328 are separated by 251 nucleotides Rv2325c: Rv2325c - Conserved hypothetical protein, at 2,597,009 to 2,597,857 Rv2325c Rv2326c: Rv2326c - Possible transmembrane ATP-binding protein ABC transporter, at 2,597,854 to 2,599,947 Rv2326c Rv2327: Rv2327 - Conserved protein, at 2,599,988 to 2,600,479 Rv2327 Rv2328: Rv2328 - PE family protein PE23, at 2,600,731 to 2,601,879 Rv2328 Position (kb) 2597 2598 2599 2600Strain fitness (log2 ratio) -2 -1 0 1 2at 2596.875 kb on - strandat 2596.891 kb on - strandat 2597.010 kb on + strandat 2597.010 kb on + strandat 2597.011 kb on - strandat 2597.011 kb on - strandat 2597.021 kb on + strandat 2597.022 kb on - strandat 2597.777 kb on - strandat 2597.962 kb on + strandat 2598.332 kb on - strand, within Rv2326cat 2598.491 kb on + strand, within Rv2326cat 2598.491 kb on + strand, within Rv2326cat 2598.586 kb on - strand, within Rv2326cat 2598.586 kb on - strand, within Rv2326cat 2598.651 kb on - strand, within Rv2326cat 2599.058 kb on - strand, within Rv2326cat 2599.105 kb on + strand, within Rv2326cat 2599.105 kb on + strand, within Rv2326cat 2599.256 kb on - strand, within Rv2326cat 2599.343 kb on + strand, within Rv2326cat 2599.344 kb on - strand, within Rv2326cat 2599.368 kb on - strand, within Rv2326cat 2599.389 kb on - strand, within Rv2326cat 2599.446 kb on + strand, within Rv2326cat 2599.619 kb on + strand, within Rv2326cat 2599.619 kb on + strand, within Rv2326cat 2599.619 kb on + strand, within Rv2326cat 2599.619 kb on + strand, within Rv2326cat 2599.619 kb on + strand, within Rv2326cat 2599.620 kb on - strand, within Rv2326cat 2599.620 kb on - strand, within Rv2326cat 2600.416 kb on - strand, within Rv2327at 2600.478 kb on - strandat 2600.478 kb on - strandat 2600.597 kb on - strandat 2600.673 kb on + strandat 2600.674 kb on - strandat 2600.674 kb on - strandat 2600.674 kb on - strandat 2600.674 kb on - strandat 2600.709 kb on + strandat 2600.709 kb on + strandat 2600.731 kb on - strandat 2600.731 kb on - strandat 2600.815 kb on + strandat 2600.902 kb on + strand, within Rv2328

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Antimycin A 0.0186 mM
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2,596,875 - -0.1
2,596,891 - -1.7
2,597,010 + -1.6
2,597,010 + -0.4
2,597,011 - -0.4
2,597,011 - +0.7
2,597,021 + +1.4
2,597,022 - -0.7
2,597,777 - +1.9
2,597,962 + -0.1
2,598,332 - Rv2326c 0.23 +0.1
2,598,491 + Rv2326c 0.30 +0.1
2,598,491 + Rv2326c 0.30 -0.1
2,598,586 - Rv2326c 0.35 -0.0
2,598,586 - Rv2326c 0.35 +0.2
2,598,651 - Rv2326c 0.38 +0.3
2,599,058 - Rv2326c 0.57 +0.5
2,599,105 + Rv2326c 0.60 +0.2
2,599,105 + Rv2326c 0.60 +0.3
2,599,256 - Rv2326c 0.67 -0.7
2,599,343 + Rv2326c 0.71 -0.0
2,599,344 - Rv2326c 0.71 -0.0
2,599,368 - Rv2326c 0.72 -0.2
2,599,389 - Rv2326c 0.73 +0.7
2,599,446 + Rv2326c 0.76 -0.0
2,599,619 + Rv2326c 0.84 +0.3
2,599,619 + Rv2326c 0.84 +0.0
2,599,619 + Rv2326c 0.84 -0.6
2,599,619 + Rv2326c 0.84 +0.8
2,599,619 + Rv2326c 0.84 +0.3
2,599,620 - Rv2326c 0.84 -0.4
2,599,620 - Rv2326c 0.84 -0.1
2,600,416 - Rv2327 0.87 +0.4
2,600,478 - -0.5
2,600,478 - -0.2
2,600,597 - +0.1
2,600,673 + -0.1
2,600,674 - +1.6
2,600,674 - +1.9
2,600,674 - +1.9
2,600,674 - -0.4
2,600,709 + -0.7
2,600,709 + -2.5
2,600,731 - +1.9
2,600,731 - -0.0
2,600,815 + -0.9
2,600,902 + Rv2328 0.15 -0.2

Or see this region's nucleotide sequence