Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2210c

Experiment: 7H9 with Antimycin A 0.0186 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2209 and Rv2210c overlap by 75 nucleotidesRv2210c and Rv2211c are separated by 71 nucleotides Rv2209: Rv2209 - Probable conserved integral membrane protein, at 2,473,400 to 2,474,938 Rv2209 Rv2210c: Rv2210c - Branched-chain amino acid transaminase IlvE, at 2,474,864 to 2,475,970 Rv2210c Rv2211c: Rv2211c - Probable aminomethyltransferase GcvT (glycine cleavage system T protein), at 2,476,042 to 2,477,181 Rv2211c Position (kb) 2474 2475 2476Strain fitness (log2 ratio) -2 -1 0 1 2at 2474.059 kb on - strand, within Rv2209at 2474.061 kb on - strand, within Rv2209at 2474.109 kb on - strand, within Rv2209at 2474.111 kb on - strand, within Rv2209at 2474.111 kb on - strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.120 kb on + strand, within Rv2209at 2474.121 kb on - strand, within Rv2209at 2474.121 kb on - strand, within Rv2209at 2474.121 kb on - strand, within Rv2209at 2474.256 kb on + strand, within Rv2209at 2474.257 kb on - strand, within Rv2209at 2474.698 kb on + strand, within Rv2209at 2474.698 kb on + strand, within Rv2209at 2474.699 kb on - strand, within Rv2209at 2474.699 kb on - strand, within Rv2209at 2474.711 kb on - strand, within Rv2209at 2474.763 kb on + strand, within Rv2209at 2474.772 kb on + strand, within Rv2209

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Antimycin A 0.0186 mM
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2,474,059 - Rv2209 0.43 -0.8
2,474,061 - Rv2209 0.43 -0.2
2,474,109 - Rv2209 0.46 +0.1
2,474,111 - Rv2209 0.46 +0.7
2,474,111 - Rv2209 0.46 -0.6
2,474,120 + Rv2209 0.47 -0.7
2,474,120 + Rv2209 0.47 +1.9
2,474,120 + Rv2209 0.47 -0.9
2,474,120 + Rv2209 0.47 +0.6
2,474,120 + Rv2209 0.47 -2.1
2,474,120 + Rv2209 0.47 +0.1
2,474,121 - Rv2209 0.47 -0.2
2,474,121 - Rv2209 0.47 +0.2
2,474,121 - Rv2209 0.47 -0.2
2,474,256 + Rv2209 0.56 -0.8
2,474,257 - Rv2209 0.56 -0.6
2,474,698 + Rv2209 0.84 -0.4
2,474,698 + Rv2209 0.84 -0.2
2,474,699 - Rv2209 0.84 -1.5
2,474,699 - Rv2209 0.84 -0.2
2,474,711 - Rv2209 0.85 -0.4
2,474,763 + Rv2209 0.89 +0.3
2,474,772 + Rv2209 0.89 -0.8

Or see this region's nucleotide sequence