Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0592

Experiment: 7H9 with Antimycin A 0.0186 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0591 and Rv0592 overlap by 4 nucleotidesRv0592 and Rv0593 overlap by 4 nucleotides Rv0591: Rv0591 - Mce-family protein Mce2C, at 689,059 to 690,504 Rv0591 Rv0592: Rv0592 - Mce-family protein Mce2D, at 690,501 to 692,027 Rv0592 Rv0593: Rv0593 - Possible Mce-family lipoprotein LprL (Mce-family lipoprotein Mce2E), at 692,024 to 693,232 Rv0593 Position (kb) 690 691 692 693Strain fitness (log2 ratio) -1 0 1at 690.413 kb on + strandat 690.413 kb on + strandat 690.413 kb on + strandat 690.493 kb on - strandat 690.493 kb on - strandat 690.654 kb on + strand, within Rv0592at 690.772 kb on - strand, within Rv0592at 690.865 kb on - strand, within Rv0592at 691.153 kb on + strand, within Rv0592at 691.364 kb on + strand, within Rv0592at 691.365 kb on - strand, within Rv0592at 691.449 kb on + strand, within Rv0592at 691.620 kb on + strand, within Rv0592at 691.621 kb on - strand, within Rv0592at 692.231 kb on + strand, within Rv0593at 692.232 kb on - strand, within Rv0593at 692.232 kb on - strand, within Rv0593at 692.232 kb on - strand, within Rv0593at 692.510 kb on + strand, within Rv0593at 692.515 kb on + strand, within Rv0593at 692.955 kb on - strand, within Rv0593at 692.976 kb on + strand, within Rv0593

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Antimycin A 0.0186 mM
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690,413 + -0.4
690,413 + -0.6
690,413 + -0.5
690,493 - -0.1
690,493 - -1.6
690,654 + Rv0592 0.10 -0.8
690,772 - Rv0592 0.18 +0.3
690,865 - Rv0592 0.24 +0.5
691,153 + Rv0592 0.43 -0.0
691,364 + Rv0592 0.57 +1.1
691,365 - Rv0592 0.57 +0.5
691,449 + Rv0592 0.62 +0.4
691,620 + Rv0592 0.73 -1.2
691,621 - Rv0592 0.73 +0.2
692,231 + Rv0593 0.17 -0.4
692,232 - Rv0593 0.17 -0.4
692,232 - Rv0593 0.17 -0.2
692,232 - Rv0593 0.17 +0.2
692,510 + Rv0593 0.40 +0.2
692,515 + Rv0593 0.41 -0.2
692,955 - Rv0593 0.77 -0.4
692,976 + Rv0593 0.79 +0.6

Or see this region's nucleotide sequence