Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3047c

Experiment: 7H9 with Antimycin A 0.0186 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3045 and Rv3046c overlap by 12 nucleotidesRv3046c and Rv3047c are separated by 333 nucleotidesRv3047c and Rv3048c are separated by 97 nucleotides Rv3045: Rv3045 - Probable NADP-dependent alcohol dehydrogenase AdhC, at 3,406,285 to 3,407,325 Rv3045 Rv3046c: Rv3046c - Conserved protein, at 3,407,314 to 3,407,688 Rv3046c Rv3047c: Rv3047c - Hypothetical protein, at 3,408,022 to 3,408,306 Rv3047c Rv3048c: Rv3048c - Ribonucleoside-diphosphate reductase (beta chain) NrdF2 (ribonucleotide reductase small subunit) (R2F protein), at 3,408,404 to 3,409,378 Rv3048c Position (kb) 3408 3409Strain fitness (log2 ratio) -1 0 1at 3407.249 kb on - strandat 3407.249 kb on - strandat 3407.249 kb on - strandat 3407.263 kb on + strandat 3407.578 kb on + strand, within Rv3046cat 3407.878 kb on + strandat 3407.879 kb on - strandat 3408.051 kb on + strand, within Rv3047cat 3408.051 kb on + strand, within Rv3047cat 3408.052 kb on - strand, within Rv3047cat 3408.052 kb on - strand, within Rv3047cat 3408.127 kb on + strand, within Rv3047cat 3408.128 kb on - strand, within Rv3047cat 3408.211 kb on + strand, within Rv3047cat 3408.326 kb on + strandat 3408.326 kb on + strandat 3408.326 kb on + strandat 3408.329 kb on + strandat 3408.329 kb on + strandat 3408.330 kb on - strandat 3408.330 kb on - strandat 3408.333 kb on + strandat 3408.333 kb on + strandat 3408.334 kb on - strandat 3408.334 kb on - strandat 3408.334 kb on - strandat 3408.334 kb on - strandat 3408.334 kb on - strandat 3408.334 kb on - strandat 3408.337 kb on + strandat 3408.338 kb on - strandat 3408.405 kb on + strandat 3408.405 kb on + strandat 3408.405 kb on + strandat 3408.405 kb on + strandat 3408.406 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Antimycin A 0.0186 mM
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3,407,249 - +0.5
3,407,249 - -0.3
3,407,249 - +0.7
3,407,263 + +0.1
3,407,578 + Rv3046c 0.70 +0.4
3,407,878 + -0.2
3,407,879 - -0.4
3,408,051 + Rv3047c 0.10 -0.6
3,408,051 + Rv3047c 0.10 +0.2
3,408,052 - Rv3047c 0.11 +1.5
3,408,052 - Rv3047c 0.11 -0.0
3,408,127 + Rv3047c 0.37 +0.7
3,408,128 - Rv3047c 0.37 +0.0
3,408,211 + Rv3047c 0.66 -0.8
3,408,326 + -0.4
3,408,326 + +0.3
3,408,326 + +0.9
3,408,329 + +0.0
3,408,329 + -0.7
3,408,330 - +1.7
3,408,330 - -1.7
3,408,333 + -0.4
3,408,333 + -0.2
3,408,334 - +0.3
3,408,334 - -0.1
3,408,334 - +0.7
3,408,334 - -0.2
3,408,334 - -0.3
3,408,334 - +1.4
3,408,337 + -0.3
3,408,338 - -0.2
3,408,405 + +0.0
3,408,405 + -0.7
3,408,405 + -0.7
3,408,405 + -1.6
3,408,406 - +0.3

Or see this region's nucleotide sequence