Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2484c

Experiment: 7H9 with 2,4-Dinitrophenol 0.1503 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2483c and Rv2484c overlap by 4 nucleotidesRv2484c and Rv2485c are separated by 228 nucleotides Rv2483c: Rv2483c - Possible transmembrane phospholipid biosynthesis bifunctional enzyme PlsC: putative L-3-phosphoserine phosphatase (O-phosphoserine phosphohydrolase) (PSP) (pspase) + 1-acyl-SN-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (lysophosphatidic acid acyltransferase) (LPAAT), at 2,789,280 to 2,791,022 Rv2483c Rv2484c: Rv2484c - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 2,791,019 to 2,792,494 Rv2484c Rv2485c: Rv2485c - Probable carboxylesterase LipQ, at 2,792,723 to 2,793,988 Rv2485c Position (kb) 2791 2792 2793Strain fitness (log2 ratio) -1 0 1 2 3at 2790.352 kb on + strand, within Rv2483cat 2790.388 kb on - strand, within Rv2483cat 2790.391 kb on + strand, within Rv2483cat 2790.392 kb on - strand, within Rv2483cat 2790.824 kb on + strand, within Rv2483cat 2791.182 kb on + strand, within Rv2484cat 2791.294 kb on - strand, within Rv2484cat 2791.298 kb on - strand, within Rv2484cat 2791.298 kb on - strand, within Rv2484cat 2791.726 kb on + strand, within Rv2484cat 2791.987 kb on + strand, within Rv2484cat 2791.988 kb on - strand, within Rv2484cat 2792.013 kb on + strand, within Rv2484cat 2792.013 kb on + strand, within Rv2484cat 2792.138 kb on + strand, within Rv2484cat 2792.138 kb on + strand, within Rv2484cat 2792.138 kb on + strand, within Rv2484cat 2792.138 kb on + strand, within Rv2484cat 2792.139 kb on - strand, within Rv2484cat 2792.439 kb on + strandat 2792.884 kb on - strand, within Rv2485cat 2792.884 kb on - strand, within Rv2485cat 2793.103 kb on + strand, within Rv2485cat 2793.103 kb on + strand, within Rv2485cat 2793.104 kb on - strand, within Rv2485cat 2793.104 kb on - strand, within Rv2485cat 2793.126 kb on + strand, within Rv2485cat 2793.126 kb on + strand, within Rv2485cat 2793.127 kb on - strand, within Rv2485cat 2793.135 kb on + strand, within Rv2485cat 2793.136 kb on - strand, within Rv2485cat 2793.369 kb on + strand, within Rv2485cat 2793.369 kb on + strand, within Rv2485cat 2793.369 kb on + strand, within Rv2485cat 2793.370 kb on - strand, within Rv2485c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2,4-Dinitrophenol 0.1503 mM
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2,790,352 + Rv2483c 0.62 -0.9
2,790,388 - Rv2483c 0.64 +3.4
2,790,391 + Rv2483c 0.64 -0.7
2,790,392 - Rv2483c 0.64 +0.2
2,790,824 + Rv2483c 0.89 -0.5
2,791,182 + Rv2484c 0.11 -0.9
2,791,294 - Rv2484c 0.19 -0.5
2,791,298 - Rv2484c 0.19 -0.2
2,791,298 - Rv2484c 0.19 +0.1
2,791,726 + Rv2484c 0.48 -1.2
2,791,987 + Rv2484c 0.66 -0.0
2,791,988 - Rv2484c 0.66 -1.0
2,792,013 + Rv2484c 0.67 +0.6
2,792,013 + Rv2484c 0.67 +0.5
2,792,138 + Rv2484c 0.76 -0.7
2,792,138 + Rv2484c 0.76 -0.4
2,792,138 + Rv2484c 0.76 -1.1
2,792,138 + Rv2484c 0.76 -1.0
2,792,139 - Rv2484c 0.76 -0.5
2,792,439 + +0.1
2,792,884 - Rv2485c 0.13 -0.4
2,792,884 - Rv2485c 0.13 -0.3
2,793,103 + Rv2485c 0.30 +0.4
2,793,103 + Rv2485c 0.30 -0.4
2,793,104 - Rv2485c 0.30 +0.2
2,793,104 - Rv2485c 0.30 -0.2
2,793,126 + Rv2485c 0.32 +0.3
2,793,126 + Rv2485c 0.32 -0.6
2,793,127 - Rv2485c 0.32 -0.2
2,793,135 + Rv2485c 0.33 +0.4
2,793,136 - Rv2485c 0.33 -0.0
2,793,369 + Rv2485c 0.51 -0.0
2,793,369 + Rv2485c 0.51 -0.5
2,793,369 + Rv2485c 0.51 -0.3
2,793,370 - Rv2485c 0.51 -1.1

Or see this region's nucleotide sequence