Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1936

Experiment: 7H9 with 2,4-Dinitrophenol 0.1503 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1935c and Rv1936 are separated by 224 nucleotidesRv1936 and Rv1937 are separated by 2 nucleotides Rv1935c: Rv1935c - Possible enoyl-CoA hydratase EchA13 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 2,186,203 to 2,187,159 Rv1935c Rv1936: Rv1936 - Possible monooxygenase, at 2,187,384 to 2,188,493 Rv1936 Rv1937: Rv1937 - Possible oxygenase, at 2,188,496 to 2,191,015 Rv1937 Position (kb) 2187 2188 2189Strain fitness (log2 ratio) -2 -1 0 1 2at 2186.594 kb on + strand, within Rv1935cat 2186.771 kb on + strand, within Rv1935cat 2186.772 kb on - strand, within Rv1935cat 2186.772 kb on - strand, within Rv1935cat 2186.774 kb on + strand, within Rv1935cat 2186.775 kb on - strand, within Rv1935cat 2187.083 kb on + strandat 2187.083 kb on + strandat 2187.084 kb on - strandat 2187.084 kb on - strandat 2187.398 kb on - strandat 2187.398 kb on - strandat 2187.435 kb on + strandat 2187.658 kb on - strand, within Rv1936at 2187.984 kb on + strand, within Rv1936at 2187.985 kb on - strand, within Rv1936at 2187.985 kb on - strand, within Rv1936at 2187.985 kb on - strand, within Rv1936at 2187.985 kb on - strand, within Rv1936at 2188.143 kb on + strand, within Rv1936at 2188.182 kb on + strand, within Rv1936at 2188.183 kb on - strand, within Rv1936at 2188.183 kb on - strand, within Rv1936at 2188.335 kb on + strand, within Rv1936at 2188.335 kb on + strand, within Rv1936at 2188.384 kb on - strandat 2188.392 kb on - strandat 2188.492 kb on - strandat 2188.492 kb on - strandat 2188.523 kb on + strandat 2188.629 kb on + strandat 2188.630 kb on - strandat 2188.630 kb on - strandat 2188.744 kb on + strandat 2188.744 kb on + strandat 2188.899 kb on - strand, within Rv1937at 2188.937 kb on + strand, within Rv1937at 2188.944 kb on + strand, within Rv1937at 2188.956 kb on - strand, within Rv1937at 2188.956 kb on - strand, within Rv1937at 2188.956 kb on - strand, within Rv1937at 2189.036 kb on + strand, within Rv1937at 2189.207 kb on + strand, within Rv1937at 2189.478 kb on - strand, within Rv1937

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2,4-Dinitrophenol 0.1503 mM
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2,186,594 + Rv1935c 0.41 -0.3
2,186,771 + Rv1935c 0.59 -0.3
2,186,772 - Rv1935c 0.59 -0.7
2,186,772 - Rv1935c 0.59 -0.4
2,186,774 + Rv1935c 0.60 -1.2
2,186,775 - Rv1935c 0.60 +0.2
2,187,083 + -0.5
2,187,083 + +0.1
2,187,084 - -0.2
2,187,084 - +0.0
2,187,398 - -0.2
2,187,398 - +0.6
2,187,435 + +0.4
2,187,658 - Rv1936 0.25 -0.0
2,187,984 + Rv1936 0.54 +1.5
2,187,985 - Rv1936 0.54 -2.7
2,187,985 - Rv1936 0.54 +1.8
2,187,985 - Rv1936 0.54 +0.1
2,187,985 - Rv1936 0.54 -0.0
2,188,143 + Rv1936 0.68 +0.3
2,188,182 + Rv1936 0.72 +1.2
2,188,183 - Rv1936 0.72 +1.3
2,188,183 - Rv1936 0.72 +1.8
2,188,335 + Rv1936 0.86 +2.1
2,188,335 + Rv1936 0.86 +0.2
2,188,384 - -0.0
2,188,392 - -0.8
2,188,492 - -0.6
2,188,492 - -0.2
2,188,523 + -0.4
2,188,629 + +0.4
2,188,630 - -0.9
2,188,630 - -0.1
2,188,744 + -0.6
2,188,744 + -0.2
2,188,899 - Rv1937 0.16 -0.4
2,188,937 + Rv1937 0.17 -0.5
2,188,944 + Rv1937 0.18 +1.8
2,188,956 - Rv1937 0.18 -0.1
2,188,956 - Rv1937 0.18 -0.8
2,188,956 - Rv1937 0.18 -0.6
2,189,036 + Rv1937 0.21 -0.1
2,189,207 + Rv1937 0.28 -0.6
2,189,478 - Rv1937 0.39 +0.1

Or see this region's nucleotide sequence