Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1675c

Experiment: 7H9 with 2,4-Dinitrophenol 0.1503 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1674c and Rv1675c are separated by 324 nucleotidesRv1675c and Rv1676 are separated by 71 nucleotidesRv1676 and Rv1677 overlap by 4 nucleotides Rv1674c: Rv1674c - Probable transcriptional regulatory protein, at 1,899,260 to 1,899,916 Rv1674c Rv1675c: Rv1675c - Probable transcriptional regulatory protein Cmr, at 1,900,241 to 1,900,975 Rv1675c Rv1676: Rv1676 - Unknown protein, at 1,901,047 to 1,901,751 Rv1676 Rv1677: Rv1677 - Probable conserved lipoprotein DsbF, at 1,901,748 to 1,902,296 Rv1677 Position (kb) 1900 1901Strain fitness (log2 ratio) -1 0 1at 1899.369 kb on + strand, within Rv1674cat 1899.659 kb on + strand, within Rv1674cat 1899.660 kb on - strand, within Rv1674cat 1899.690 kb on + strand, within Rv1674cat 1899.950 kb on - strandat 1900.180 kb on + strandat 1900.180 kb on + strandat 1900.183 kb on + strandat 1900.183 kb on + strandat 1900.259 kb on + strandat 1900.547 kb on + strand, within Rv1675cat 1900.721 kb on + strand, within Rv1675cat 1901.164 kb on + strand, within Rv1676at 1901.165 kb on - strand, within Rv1676at 1901.170 kb on - strand, within Rv1676at 1901.181 kb on + strand, within Rv1676at 1901.467 kb on + strand, within Rv1676at 1901.668 kb on + strand, within Rv1676at 1901.778 kb on - strandat 1901.783 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2,4-Dinitrophenol 0.1503 mM
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1,899,369 + Rv1674c 0.17 -0.1
1,899,659 + Rv1674c 0.61 +1.2
1,899,660 - Rv1674c 0.61 -0.7
1,899,690 + Rv1674c 0.65 -0.1
1,899,950 - -0.6
1,900,180 + -1.5
1,900,180 + +0.6
1,900,183 + -0.3
1,900,183 + -0.1
1,900,259 + +0.3
1,900,547 + Rv1675c 0.42 +1.6
1,900,721 + Rv1675c 0.65 +0.0
1,901,164 + Rv1676 0.17 -0.2
1,901,165 - Rv1676 0.17 -0.6
1,901,170 - Rv1676 0.17 -0.3
1,901,181 + Rv1676 0.19 -1.0
1,901,467 + Rv1676 0.60 -0.5
1,901,668 + Rv1676 0.88 -0.0
1,901,778 - -0.1
1,901,783 - -0.7

Or see this region's nucleotide sequence