Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3159c

Experiment: 7H9 with 2,4-Dinitrophenol 0.1503 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3158 and Rv3159c are separated by 5 nucleotidesRv3159c and Rv3160c are separated by 174 nucleotidesRv3160c and Rv3161c are separated by 10 nucleotides Rv3158: Rv3158 - Probable NADH dehydrogenase I (chain N) NuoN (NADH-ubiquinone oxidoreductase chain N), at 3,525,790 to 3,527,385 Rv3158 Rv3159c: Rv3159c - PPE family protein PPE53, at 3,527,391 to 3,529,163 Rv3159c Rv3160c: Rv3160c - Possible transcriptional regulatory protein (probably TetR-family), at 3,529,338 to 3,529,979 Rv3160c Rv3161c: Rv3161c - Possible dioxygenase, at 3,529,990 to 3,531,138 Rv3161c Position (kb) 3527 3528 3529 3530Strain fitness (log2 ratio) -2 -1 0 1 2at 3526.408 kb on + strand, within Rv3158at 3526.572 kb on - strand, within Rv3158at 3526.572 kb on - strand, within Rv3158at 3526.572 kb on - strand, within Rv3158at 3526.574 kb on + strand, within Rv3158at 3526.574 kb on + strand, within Rv3158at 3526.575 kb on - strand, within Rv3158at 3526.575 kb on - strand, within Rv3158at 3526.575 kb on - strand, within Rv3158at 3526.705 kb on + strand, within Rv3158at 3526.706 kb on - strand, within Rv3158at 3526.818 kb on + strand, within Rv3158at 3526.818 kb on + strand, within Rv3158at 3526.818 kb on + strand, within Rv3158at 3526.819 kb on - strand, within Rv3158at 3526.819 kb on - strand, within Rv3158at 3526.819 kb on - strand, within Rv3158at 3526.819 kb on - strand, within Rv3158at 3526.829 kb on - strand, within Rv3158at 3526.856 kb on + strand, within Rv3158at 3526.861 kb on - strand, within Rv3158at 3526.861 kb on - strand, within Rv3158at 3526.861 kb on - strand, within Rv3158at 3527.040 kb on + strand, within Rv3158at 3527.197 kb on + strand, within Rv3158at 3527.203 kb on + strand, within Rv3158at 3527.204 kb on - strand, within Rv3158at 3527.300 kb on + strandat 3527.300 kb on + strandat 3527.309 kb on + strandat 3527.309 kb on + strandat 3527.589 kb on - strand, within Rv3159cat 3527.624 kb on - strand, within Rv3159cat 3528.514 kb on - strand, within Rv3159cat 3528.514 kb on - strand, within Rv3159cat 3528.551 kb on - strand, within Rv3159cat 3528.745 kb on + strand, within Rv3159cat 3528.745 kb on + strand, within Rv3159cat 3528.746 kb on - strand, within Rv3159cat 3528.746 kb on - strand, within Rv3159cat 3528.746 kb on - strand, within Rv3159cat 3528.821 kb on + strand, within Rv3159cat 3528.821 kb on + strand, within Rv3159cat 3528.822 kb on - strand, within Rv3159cat 3528.949 kb on + strand, within Rv3159cat 3529.234 kb on + strandat 3529.234 kb on + strandat 3529.234 kb on + strandat 3529.234 kb on + strandat 3529.235 kb on - strandat 3529.247 kb on - strandat 3529.340 kb on - strandat 3529.606 kb on - strand, within Rv3160cat 3529.838 kb on - strand, within Rv3160cat 3529.991 kb on + strandat 3529.991 kb on + strandat 3530.039 kb on + strandat 3530.073 kb on + strandat 3530.073 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2,4-Dinitrophenol 0.1503 mM
remove
3,526,408 + Rv3158 0.39 -1.6
3,526,572 - Rv3158 0.49 -0.5
3,526,572 - Rv3158 0.49 -0.3
3,526,572 - Rv3158 0.49 +0.2
3,526,574 + Rv3158 0.49 -0.6
3,526,574 + Rv3158 0.49 -2.4
3,526,575 - Rv3158 0.49 -1.8
3,526,575 - Rv3158 0.49 -2.1
3,526,575 - Rv3158 0.49 -2.0
3,526,705 + Rv3158 0.57 -2.6
3,526,706 - Rv3158 0.57 -0.6
3,526,818 + Rv3158 0.64 -1.2
3,526,818 + Rv3158 0.64 -0.5
3,526,818 + Rv3158 0.64 -0.9
3,526,819 - Rv3158 0.64 +1.8
3,526,819 - Rv3158 0.64 -1.5
3,526,819 - Rv3158 0.64 +0.2
3,526,819 - Rv3158 0.64 -1.5
3,526,829 - Rv3158 0.65 +0.2
3,526,856 + Rv3158 0.67 -1.0
3,526,861 - Rv3158 0.67 +1.8
3,526,861 - Rv3158 0.67 -0.2
3,526,861 - Rv3158 0.67 -0.8
3,527,040 + Rv3158 0.78 +0.2
3,527,197 + Rv3158 0.88 +1.2
3,527,203 + Rv3158 0.89 -0.8
3,527,204 - Rv3158 0.89 -0.5
3,527,300 + -1.4
3,527,300 + -0.9
3,527,309 + -0.3
3,527,309 + -0.2
3,527,589 - Rv3159c 0.11 -0.3
3,527,624 - Rv3159c 0.13 -0.0
3,528,514 - Rv3159c 0.63 -0.2
3,528,514 - Rv3159c 0.63 -0.8
3,528,551 - Rv3159c 0.65 -0.2
3,528,745 + Rv3159c 0.76 -0.5
3,528,745 + Rv3159c 0.76 -0.2
3,528,746 - Rv3159c 0.76 -1.9
3,528,746 - Rv3159c 0.76 +0.1
3,528,746 - Rv3159c 0.76 -0.8
3,528,821 + Rv3159c 0.81 -1.4
3,528,821 + Rv3159c 0.81 -1.7
3,528,822 - Rv3159c 0.81 +0.4
3,528,949 + Rv3159c 0.88 -0.0
3,529,234 + +0.3
3,529,234 + -0.1
3,529,234 + -0.7
3,529,234 + +0.1
3,529,235 - -0.7
3,529,247 - +0.1
3,529,340 - -0.6
3,529,606 - Rv3160c 0.42 -1.1
3,529,838 - Rv3160c 0.78 -0.2
3,529,991 + -1.4
3,529,991 + -0.4
3,530,039 + -0.8
3,530,073 + +1.6
3,530,073 + -1.5

Or see this region's nucleotide sequence