Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3609c

Experiment: 7H9 with Phenazine ethosulfate 0.0137 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3607c and Rv3608c overlap by 8 nucleotidesRv3608c and Rv3609c overlap by 4 nucleotidesRv3609c and Rv3610c are separated by 15 nucleotides Rv3607c: Rv3607c - Probable dihydroneopterin aldolase FolB (DHNA), at 4,048,744 to 4,049,145 Rv3607c Rv3608c: Rv3608c - Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1), at 4,049,138 to 4,049,980 Rv3608c Rv3609c: Rv3609c - GTP cyclohydrolase I FolE (GTP-ch-I), at 4,049,977 to 4,050,585 Rv3609c Rv3610c: Rv3610c - Membrane-bound protease FtsH (cell division protein), at 4,050,601 to 4,052,883 Rv3610c Position (kb) 4049 4050 4051Strain fitness (log2 ratio) -1 0 1at 4050.729 kb on - strandat 4050.729 kb on - strandat 4051.270 kb on - strand, within Rv3610cat 4051.555 kb on - strand, within Rv3610c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine ethosulfate 0.0137 mM
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4,050,729 - -0.8
4,050,729 - -1.0
4,051,270 - Rv3610c 0.29 -1.1
4,051,555 - Rv3610c 0.42 -0.8

Or see this region's nucleotide sequence