Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0269c

Experiment: 7H9 with Phenazine ethosulfate 0.0137 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0267 and Rv0268c are separated by 41 nucleotidesRv0268c and Rv0269c are separated by 64 nucleotidesRv0269c and Rv0270 are separated by 35 nucleotides Rv0267: Rv0267 - Probable integral membrane nitrite extrusion protein NarU (nitrite facilitator), at 321,331 to 322,722 Rv0267 Rv0268c: Rv0268c - Hypothetical protein, at 322,764 to 323,273 Rv0268c Rv0269c: Rv0269c - Conserved hypothetical protein, at 323,338 to 324,531 Rv0269c Rv0270: Rv0270 - Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 324,567 to 326,249 Rv0270 Position (kb) 323 324 325Strain fitness (log2 ratio) -2 -1 0 1 2 3at 322.399 kb on + strand, within Rv0267at 322.586 kb on - strandat 322.614 kb on + strandat 322.615 kb on - strandat 322.676 kb on - strandat 322.681 kb on + strandat 322.690 kb on - strandat 322.720 kb on + strandat 322.721 kb on - strandat 322.721 kb on - strandat 322.725 kb on - strandat 322.878 kb on + strand, within Rv0268cat 322.879 kb on - strand, within Rv0268cat 322.888 kb on + strand, within Rv0268cat 322.977 kb on + strand, within Rv0268cat 322.997 kb on + strand, within Rv0268cat 322.997 kb on + strand, within Rv0268cat 322.997 kb on + strand, within Rv0268cat 322.997 kb on + strand, within Rv0268cat 322.998 kb on - strand, within Rv0268cat 322.998 kb on - strand, within Rv0268cat 323.000 kb on + strand, within Rv0268cat 323.001 kb on - strand, within Rv0268cat 323.001 kb on - strand, within Rv0268cat 323.008 kb on - strand, within Rv0268cat 323.026 kb on - strand, within Rv0268cat 323.026 kb on - strand, within Rv0268cat 323.026 kb on - strand, within Rv0268cat 323.088 kb on + strand, within Rv0268cat 323.089 kb on - strand, within Rv0268cat 323.100 kb on + strand, within Rv0268cat 323.101 kb on - strand, within Rv0268cat 323.101 kb on - strand, within Rv0268cat 323.101 kb on - strand, within Rv0268cat 323.121 kb on + strand, within Rv0268cat 323.121 kb on + strand, within Rv0268cat 323.239 kb on - strandat 323.239 kb on - strandat 323.281 kb on - strandat 323.290 kb on + strandat 323.290 kb on + strandat 323.291 kb on - strandat 323.307 kb on + strandat 323.307 kb on + strandat 323.308 kb on - strandat 323.308 kb on - strandat 323.308 kb on - strandat 323.308 kb on - strandat 323.308 kb on - strandat 323.310 kb on + strandat 323.310 kb on + strandat 323.310 kb on + strandat 323.310 kb on + strandat 323.310 kb on + strandat 323.310 kb on + strandat 323.311 kb on - strandat 323.311 kb on - strandat 323.311 kb on - strandat 323.311 kb on - strandat 323.312 kb on + strandat 323.313 kb on - strandat 323.313 kb on - strandat 323.313 kb on - strandat 323.357 kb on + strandat 323.358 kb on - strandat 323.523 kb on - strand, within Rv0269cat 323.979 kb on - strand, within Rv0269cat 324.248 kb on + strand, within Rv0269cat 324.248 kb on + strand, within Rv0269cat 324.398 kb on + strand, within Rv0269cat 324.399 kb on - strand, within Rv0269cat 324.401 kb on + strand, within Rv0269cat 324.425 kb on + strandat 324.425 kb on + strandat 324.534 kb on + strandat 324.556 kb on - strandat 324.556 kb on - strandat 324.573 kb on - strandat 324.630 kb on + strandat 324.630 kb on + strandat 324.630 kb on + strandat 324.661 kb on - strandat 324.714 kb on + strandat 324.715 kb on - strandat 324.875 kb on - strand, within Rv0270at 324.875 kb on - strand, within Rv0270at 324.952 kb on - strand, within Rv0270at 325.056 kb on + strand, within Rv0270at 325.057 kb on - strand, within Rv0270at 325.068 kb on + strand, within Rv0270at 325.069 kb on - strand, within Rv0270at 325.507 kb on + strand, within Rv0270at 325.508 kb on - strand, within Rv0270at 325.508 kb on - strand, within Rv0270at 325.508 kb on - strand, within Rv0270

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine ethosulfate 0.0137 mM
remove
322,399 + Rv0267 0.77 -0.8
322,586 - -0.7
322,614 + -0.2
322,615 - -0.3
322,676 - -0.1
322,681 + -0.5
322,690 - -0.4
322,720 + -0.5
322,721 - -1.7
322,721 - +1.7
322,725 - -0.4
322,878 + Rv0268c 0.22 -0.6
322,879 - Rv0268c 0.23 +1.7
322,888 + Rv0268c 0.24 -0.6
322,977 + Rv0268c 0.42 -0.4
322,997 + Rv0268c 0.46 +0.0
322,997 + Rv0268c 0.46 -0.7
322,997 + Rv0268c 0.46 +0.3
322,997 + Rv0268c 0.46 -1.2
322,998 - Rv0268c 0.46 -0.4
322,998 - Rv0268c 0.46 -0.2
323,000 + Rv0268c 0.46 -0.2
323,001 - Rv0268c 0.46 -0.4
323,001 - Rv0268c 0.46 -0.3
323,008 - Rv0268c 0.48 +2.3
323,026 - Rv0268c 0.51 +1.7
323,026 - Rv0268c 0.51 +0.2
323,026 - Rv0268c 0.51 +0.5
323,088 + Rv0268c 0.64 -0.0
323,089 - Rv0268c 0.64 -1.6
323,100 + Rv0268c 0.66 +0.2
323,101 - Rv0268c 0.66 -1.6
323,101 - Rv0268c 0.66 -0.5
323,101 - Rv0268c 0.66 -0.6
323,121 + Rv0268c 0.70 -0.1
323,121 + Rv0268c 0.70 -0.7
323,239 - +0.7
323,239 - +1.4
323,281 - +0.2
323,290 + -0.1
323,290 + +0.8
323,291 - +0.4
323,307 + +0.5
323,307 + +0.3
323,308 - -0.1
323,308 - -0.3
323,308 - -0.9
323,308 - -0.3
323,308 - -0.3
323,310 + -0.3
323,310 + +0.8
323,310 + -0.1
323,310 + +3.7
323,310 + -0.3
323,310 + -0.5
323,311 - +1.1
323,311 - -0.0
323,311 - +0.8
323,311 - -0.3
323,312 + +0.1
323,313 - -0.9
323,313 - +0.1
323,313 - -0.2
323,357 + -0.3
323,358 - +0.2
323,523 - Rv0269c 0.15 -0.2
323,979 - Rv0269c 0.54 +0.2
324,248 + Rv0269c 0.76 -1.2
324,248 + Rv0269c 0.76 -0.4
324,398 + Rv0269c 0.89 -1.1
324,399 - Rv0269c 0.89 -0.3
324,401 + Rv0269c 0.89 -1.7
324,425 + +1.0
324,425 + +0.1
324,534 + -0.7
324,556 - -0.6
324,556 - -0.3
324,573 - -0.2
324,630 + -1.2
324,630 + -2.3
324,630 + -0.8
324,661 - -0.8
324,714 + -0.2
324,715 - -2.3
324,875 - Rv0270 0.18 -0.6
324,875 - Rv0270 0.18 -0.3
324,952 - Rv0270 0.23 +0.6
325,056 + Rv0270 0.29 -1.1
325,057 - Rv0270 0.29 -1.7
325,068 + Rv0270 0.30 +0.2
325,069 - Rv0270 0.30 -0.0
325,507 + Rv0270 0.56 -0.1
325,508 - Rv0270 0.56 -1.1
325,508 - Rv0270 0.56 +0.2
325,508 - Rv0270 0.56 -1.8

Or see this region's nucleotide sequence