Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1431

Experiment: 7H9 with Phenazine ethosulfate 0.0137 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1430 and Rv1431 are separated by 110 nucleotidesRv1431 and Rv1432 overlap by 4 nucleotides Rv1430: Rv1430 - PE family protein PE16, at 1,606,386 to 1,607,972 Rv1430 Rv1431: Rv1431 - Conserved membrane protein, at 1,608,083 to 1,609,852 Rv1431 Rv1432: Rv1432 - Probable dehydrogenase, at 1,609,849 to 1,611,270 Rv1432 Position (kb) 1608 1609 1610Strain fitness (log2 ratio) -1 0 1 2at 1607.196 kb on + strand, within Rv1430at 1607.196 kb on + strand, within Rv1430at 1607.236 kb on - strand, within Rv1430at 1607.299 kb on - strand, within Rv1430at 1607.373 kb on + strand, within Rv1430at 1607.741 kb on + strand, within Rv1430at 1607.894 kb on - strandat 1608.038 kb on + strandat 1608.046 kb on - strandat 1608.180 kb on + strandat 1608.180 kb on + strandat 1608.222 kb on - strandat 1608.242 kb on + strandat 1608.534 kb on - strand, within Rv1431at 1608.648 kb on + strand, within Rv1431at 1608.725 kb on + strand, within Rv1431at 1608.726 kb on - strand, within Rv1431at 1608.726 kb on - strand, within Rv1431at 1609.154 kb on + strand, within Rv1431at 1609.154 kb on + strand, within Rv1431at 1609.154 kb on + strand, within Rv1431at 1609.158 kb on + strand, within Rv1431at 1609.159 kb on - strand, within Rv1431at 1609.295 kb on + strand, within Rv1431at 1609.749 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Phenazine ethosulfate 0.0137 mM
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1,607,196 + Rv1430 0.51 -0.4
1,607,196 + Rv1430 0.51 -0.1
1,607,236 - Rv1430 0.54 -0.1
1,607,299 - Rv1430 0.58 -0.2
1,607,373 + Rv1430 0.62 +0.6
1,607,741 + Rv1430 0.85 +2.1
1,607,894 - -0.5
1,608,038 + -0.6
1,608,046 - -0.2
1,608,180 + +0.3
1,608,180 + +1.2
1,608,222 - +0.2
1,608,242 + -1.1
1,608,534 - Rv1431 0.25 -0.8
1,608,648 + Rv1431 0.32 +2.1
1,608,725 + Rv1431 0.36 -0.7
1,608,726 - Rv1431 0.36 +0.2
1,608,726 - Rv1431 0.36 -0.1
1,609,154 + Rv1431 0.61 +0.1
1,609,154 + Rv1431 0.61 -1.1
1,609,154 + Rv1431 0.61 -1.5
1,609,158 + Rv1431 0.61 +0.4
1,609,159 - Rv1431 0.61 -0.7
1,609,295 + Rv1431 0.68 -1.2
1,609,749 - +1.6

Or see this region's nucleotide sequence