Experiment: 7H9 with Novobiocin 0.004 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3910 and Rv3911 are separated by 34 nucleotides Rv3911 and Rv3912 are separated by 15 nucleotides Rv3912 and Rv3913 are separated by 93 nucleotides
Rv3910: Rv3910 - Probable conserved transmembrane protein, at 4,396,597 to 4,400,151
Rv3910
Rv3911: Rv3911 - Possible alternative RNA polymerase sigma factor SigM, at 4,400,186 to 4,400,854
Rv3911
Rv3912: Rv3912 - Hypothetical alanine rich protein, at 4,400,870 to 4,401,634
Rv3912
Rv3913: Rv3913 - Probable thioredoxin reductase TrxB2 (TRXR) (TR), at 4,401,728 to 4,402,735
Rv3913
Position (kb)
4400
4401
4402 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 4400.082 kb on + strand at 4400.082 kb on + strand at 4400.185 kb on + strand at 4400.204 kb on + strand at 4400.325 kb on + strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.326 kb on - strand, within Rv3911 at 4400.520 kb on + strand, within Rv3911 at 4400.520 kb on + strand, within Rv3911 at 4400.798 kb on - strand at 4400.798 kb on - strand at 4401.135 kb on + strand, within Rv3912 at 4401.136 kb on - strand, within Rv3912 at 4401.136 kb on - strand, within Rv3912 at 4401.392 kb on + strand, within Rv3912 at 4401.433 kb on + strand, within Rv3912
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM remove 4,400,082 + -3.0 4,400,082 + -1.5 4,400,185 + -0.1 4,400,204 + -0.1 4,400,325 + Rv3911 0.21 -0.0 4,400,326 - Rv3911 0.21 +0.5 4,400,326 - Rv3911 0.21 +1.6 4,400,326 - Rv3911 0.21 -0.7 4,400,520 + Rv3911 0.50 -0.7 4,400,520 + Rv3911 0.50 -0.3 4,400,798 - +0.3 4,400,798 - -0.3 4,401,135 + Rv3912 0.35 -1.2 4,401,136 - Rv3912 0.35 -0.2 4,401,136 - Rv3912 0.35 +0.1 4,401,392 + Rv3912 0.68 -1.7 4,401,433 + Rv3912 0.74 -0.9
Or see this region's nucleotide sequence