Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2884

Experiment: 7H9 with Novobiocin 0.004 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2883c and Rv2884 are separated by 234 nucleotidesRv2884 and Rv2885c are separated by 14 nucleotides Rv2883c: Rv2883c - Probable uridylate kinase PyrH (UK) (uridine monophosphate kinase) (UMP kinase), at 3,192,373 to 3,193,158 Rv2883c Rv2884: Rv2884 - Probable transcriptional regulatory protein, at 3,193,393 to 3,194,151 Rv2884 Rv2885c: Rv2885c - Probable transposase, at 3,194,166 to 3,195,548 Rv2885c Position (kb) 3193 3194 3195Strain fitness (log2 ratio) -2 -1 0 1 2at 3193.254 kb on - strandat 3193.254 kb on - strandat 3193.339 kb on + strandat 3193.461 kb on - strandat 3193.467 kb on + strandat 3193.468 kb on - strandat 3193.645 kb on - strand, within Rv2884at 3193.849 kb on + strand, within Rv2884at 3193.999 kb on - strand, within Rv2884at 3194.015 kb on + strand, within Rv2884at 3194.015 kb on + strand, within Rv2884at 3194.083 kb on + strandat 3194.084 kb on - strandat 3194.084 kb on - strandat 3194.086 kb on - strandat 3194.501 kb on - strand, within Rv2885cat 3194.501 kb on - strand, within Rv2885cat 3194.622 kb on - strand, within Rv2885cat 3195.047 kb on + strand, within Rv2885cat 3195.048 kb on - strand, within Rv2885c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM
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3,193,254 - +0.2
3,193,254 - -0.7
3,193,339 + -0.4
3,193,461 - +0.3
3,193,467 + +0.5
3,193,468 - -0.8
3,193,645 - Rv2884 0.33 -1.8
3,193,849 + Rv2884 0.60 -0.1
3,193,999 - Rv2884 0.80 -0.9
3,194,015 + Rv2884 0.82 -0.1
3,194,015 + Rv2884 0.82 -0.6
3,194,083 + +0.5
3,194,084 - +0.6
3,194,084 - +1.8
3,194,086 - +0.1
3,194,501 - Rv2885c 0.24 -0.3
3,194,501 - Rv2885c 0.24 -0.6
3,194,622 - Rv2885c 0.33 +0.0
3,195,047 + Rv2885c 0.64 -0.0
3,195,048 - Rv2885c 0.64 +0.0

Or see this region's nucleotide sequence