Experiment: 7H9 with Novobiocin 0.004 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0743c and Rv0744c overlap by 4 nucleotides Rv0744c and Rv0745 are separated by 207 nucleotides Rv0745 and Rv0746 are separated by 19 nucleotides
Rv0743c: Rv0743c - Hypothetical protein, at 833,886 to 834,443
Rv0743c
Rv0744c: Rv0744c - Possible transcriptional regulatory protein, at 834,440 to 834,946
Rv0744c
Rv0745: Rv0745 - Conserved hypothetical protein, at 835,154 to 835,681
Rv0745
Rv0746: Rv0746 - PE-PGRS family protein PE_PGRS9, at 835,701 to 838,052
Rv0746
Position (kb)
835
836 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 834.182 kb on + strand, within Rv0743c at 834.182 kb on + strand, within Rv0743c at 834.182 kb on + strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.183 kb on - strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.186 kb on + strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.187 kb on - strand, within Rv0743c at 834.199 kb on + strand, within Rv0743c at 834.327 kb on + strand, within Rv0743c at 834.328 kb on - strand, within Rv0743c at 834.373 kb on - strand, within Rv0743c at 834.524 kb on + strand, within Rv0744c at 834.639 kb on + strand, within Rv0744c at 834.670 kb on + strand, within Rv0744c at 834.909 kb on - strand at 835.016 kb on + strand at 835.017 kb on - strand at 835.060 kb on + strand at 835.061 kb on - strand at 835.130 kb on - strand at 835.222 kb on + strand, within Rv0745 at 835.514 kb on + strand, within Rv0745 at 835.621 kb on + strand, within Rv0745 at 835.621 kb on + strand, within Rv0745 at 835.644 kb on + strand at 835.644 kb on + strand at 835.644 kb on + strand at 835.645 kb on - strand at 835.645 kb on - strand at 835.884 kb on + strand at 835.884 kb on + strand at 835.884 kb on + strand at 835.885 kb on - strand at 835.885 kb on - strand at 835.959 kb on + strand, within Rv0746 at 836.145 kb on - strand, within Rv0746 at 836.261 kb on - strand, within Rv0746 at 836.261 kb on - strand, within Rv0746 at 836.261 kb on - strand, within Rv0746 at 836.620 kb on + strand, within Rv0746
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM remove 834,182 + Rv0743c 0.53 -0.3 834,182 + Rv0743c 0.53 -0.5 834,182 + Rv0743c 0.53 -0.1 834,183 - Rv0743c 0.53 -0.2 834,183 - Rv0743c 0.53 +1.2 834,183 - Rv0743c 0.53 -0.9 834,186 + Rv0743c 0.54 +0.1 834,186 + Rv0743c 0.54 +0.6 834,186 + Rv0743c 0.54 +0.9 834,187 - Rv0743c 0.54 +0.3 834,187 - Rv0743c 0.54 -0.1 834,187 - Rv0743c 0.54 -0.5 834,187 - Rv0743c 0.54 -1.6 834,199 + Rv0743c 0.56 +0.8 834,327 + Rv0743c 0.79 -1.0 834,328 - Rv0743c 0.79 -0.3 834,373 - Rv0743c 0.87 -1.4 834,524 + Rv0744c 0.17 +1.0 834,639 + Rv0744c 0.39 -0.3 834,670 + Rv0744c 0.45 -1.1 834,909 - -0.1 835,016 + -0.5 835,017 - -0.6 835,060 + -0.5 835,061 - -0.8 835,130 - -0.3 835,222 + Rv0745 0.13 -0.8 835,514 + Rv0745 0.68 -1.0 835,621 + Rv0745 0.88 -0.7 835,621 + Rv0745 0.88 -0.9 835,644 + +0.1 835,644 + -0.5 835,644 + -0.2 835,645 - -1.4 835,645 - -0.5 835,884 + -0.5 835,884 + +2.7 835,884 + -0.0 835,885 - -0.7 835,885 - -0.9 835,959 + Rv0746 0.11 -2.9 836,145 - Rv0746 0.19 -0.9 836,261 - Rv0746 0.24 -0.6 836,261 - Rv0746 0.24 -1.2 836,261 - Rv0746 0.24 -0.5 836,620 + Rv0746 0.39 -0.9
Or see this region's nucleotide sequence