Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0745

Experiment: 7H9 with Novobiocin 0.004 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0743c and Rv0744c overlap by 4 nucleotidesRv0744c and Rv0745 are separated by 207 nucleotidesRv0745 and Rv0746 are separated by 19 nucleotides Rv0743c: Rv0743c - Hypothetical protein, at 833,886 to 834,443 Rv0743c Rv0744c: Rv0744c - Possible transcriptional regulatory protein, at 834,440 to 834,946 Rv0744c Rv0745: Rv0745 - Conserved hypothetical protein, at 835,154 to 835,681 Rv0745 Rv0746: Rv0746 - PE-PGRS family protein PE_PGRS9, at 835,701 to 838,052 Rv0746 Position (kb) 835 836Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 834.182 kb on + strand, within Rv0743cat 834.182 kb on + strand, within Rv0743cat 834.182 kb on + strand, within Rv0743cat 834.183 kb on - strand, within Rv0743cat 834.183 kb on - strand, within Rv0743cat 834.183 kb on - strand, within Rv0743cat 834.186 kb on + strand, within Rv0743cat 834.186 kb on + strand, within Rv0743cat 834.186 kb on + strand, within Rv0743cat 834.187 kb on - strand, within Rv0743cat 834.187 kb on - strand, within Rv0743cat 834.187 kb on - strand, within Rv0743cat 834.187 kb on - strand, within Rv0743cat 834.199 kb on + strand, within Rv0743cat 834.327 kb on + strand, within Rv0743cat 834.328 kb on - strand, within Rv0743cat 834.373 kb on - strand, within Rv0743cat 834.524 kb on + strand, within Rv0744cat 834.639 kb on + strand, within Rv0744cat 834.670 kb on + strand, within Rv0744cat 834.909 kb on - strandat 835.016 kb on + strandat 835.017 kb on - strandat 835.060 kb on + strandat 835.061 kb on - strandat 835.130 kb on - strandat 835.222 kb on + strand, within Rv0745at 835.514 kb on + strand, within Rv0745at 835.621 kb on + strand, within Rv0745at 835.621 kb on + strand, within Rv0745at 835.644 kb on + strandat 835.644 kb on + strandat 835.644 kb on + strandat 835.645 kb on - strandat 835.645 kb on - strandat 835.884 kb on + strandat 835.884 kb on + strandat 835.884 kb on + strandat 835.885 kb on - strandat 835.885 kb on - strandat 835.959 kb on + strand, within Rv0746at 836.145 kb on - strand, within Rv0746at 836.261 kb on - strand, within Rv0746at 836.261 kb on - strand, within Rv0746at 836.261 kb on - strand, within Rv0746at 836.620 kb on + strand, within Rv0746

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM
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834,182 + Rv0743c 0.53 -0.3
834,182 + Rv0743c 0.53 -0.5
834,182 + Rv0743c 0.53 -0.1
834,183 - Rv0743c 0.53 -0.2
834,183 - Rv0743c 0.53 +1.2
834,183 - Rv0743c 0.53 -0.9
834,186 + Rv0743c 0.54 +0.1
834,186 + Rv0743c 0.54 +0.6
834,186 + Rv0743c 0.54 +0.9
834,187 - Rv0743c 0.54 +0.3
834,187 - Rv0743c 0.54 -0.1
834,187 - Rv0743c 0.54 -0.5
834,187 - Rv0743c 0.54 -1.6
834,199 + Rv0743c 0.56 +0.8
834,327 + Rv0743c 0.79 -1.0
834,328 - Rv0743c 0.79 -0.3
834,373 - Rv0743c 0.87 -1.4
834,524 + Rv0744c 0.17 +1.0
834,639 + Rv0744c 0.39 -0.3
834,670 + Rv0744c 0.45 -1.1
834,909 - -0.1
835,016 + -0.5
835,017 - -0.6
835,060 + -0.5
835,061 - -0.8
835,130 - -0.3
835,222 + Rv0745 0.13 -0.8
835,514 + Rv0745 0.68 -1.0
835,621 + Rv0745 0.88 -0.7
835,621 + Rv0745 0.88 -0.9
835,644 + +0.1
835,644 + -0.5
835,644 + -0.2
835,645 - -1.4
835,645 - -0.5
835,884 + -0.5
835,884 + +2.7
835,884 + -0.0
835,885 - -0.7
835,885 - -0.9
835,959 + Rv0746 0.11 -2.9
836,145 - Rv0746 0.19 -0.9
836,261 - Rv0746 0.24 -0.6
836,261 - Rv0746 0.24 -1.2
836,261 - Rv0746 0.24 -0.5
836,620 + Rv0746 0.39 -0.9

Or see this region's nucleotide sequence