Experiment: 7H9 with Novobiocin 0.004 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0462 and Rv0463 are separated by 7 nucleotides Rv0463 and Rv0464c are separated by 3 nucleotides Rv0464c and Rv0465c overlap by 4 nucleotides
Rv0462: Rv0462 - Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphorase), at 552,614 to 554,008
Rv0462
Rv0463: Rv0463 - Probable conserved membrane protein, at 554,016 to 554,309
Rv0463
Rv0464c: Rv0464c - Conserved protein, at 554,313 to 554,885
Rv0464c
Rv0465c: Rv0465c - Probable transcriptional regulatory protein, at 554,882 to 556,306
Rv0465c
Position (kb) 554
555 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 554.085 kb on + strand, within Rv0463 at 554.085 kb on + strand, within Rv0463 at 554.085 kb on + strand, within Rv0463 at 554.086 kb on - strand, within Rv0463 at 554.159 kb on - strand, within Rv0463 at 554.159 kb on - strand, within Rv0463 at 554.301 kb on + strand at 554.314 kb on + strand at 554.315 kb on - strand at 554.315 kb on - strand at 554.487 kb on + strand, within Rv0464c at 554.584 kb on - strand, within Rv0464c at 554.641 kb on - strand, within Rv0464c at 554.713 kb on + strand, within Rv0464c at 554.713 kb on + strand, within Rv0464c at 554.737 kb on + strand, within Rv0464c at 554.737 kb on + strand, within Rv0464c at 554.738 kb on - strand, within Rv0464c at 554.885 kb on + strand at 554.885 kb on + strand at 554.886 kb on - strand at 554.886 kb on - strand at 555.011 kb on - strand at 555.026 kb on - strand, within Rv0465c at 555.026 kb on - strand, within Rv0465c at 555.061 kb on - strand, within Rv0465c at 555.116 kb on - strand, within Rv0465c at 555.129 kb on + strand, within Rv0465c at 555.171 kb on + strand, within Rv0465c at 555.371 kb on + strand, within Rv0465c at 555.371 kb on + strand, within Rv0465c at 555.372 kb on - strand, within Rv0465c at 555.372 kb on - strand, within Rv0465c at 555.372 kb on - strand, within Rv0465c at 555.403 kb on - strand, within Rv0465c at 555.414 kb on + strand, within Rv0465c at 555.415 kb on - strand, within Rv0465c at 555.505 kb on - strand, within Rv0465c at 555.505 kb on - strand, within Rv0465c at 555.505 kb on - strand, within Rv0465c at 555.508 kb on + strand, within Rv0465c at 555.509 kb on - strand, within Rv0465c at 555.600 kb on + strand, within Rv0465c at 555.601 kb on - strand, within Rv0465c at 555.731 kb on + strand, within Rv0465c at 555.732 kb on - strand, within Rv0465c at 555.732 kb on - strand, within Rv0465c at 555.836 kb on + strand, within Rv0465c at 555.837 kb on - strand, within Rv0465c at 555.837 kb on - strand, within Rv0465c at 555.837 kb on - strand, within Rv0465c at 555.837 kb on - strand, within Rv0465c at 555.840 kb on + strand, within Rv0465c at 555.855 kb on + strand, within Rv0465c at 555.855 kb on + strand, within Rv0465c at 555.855 kb on + strand, within Rv0465c at 555.855 kb on + strand, within Rv0465c at 555.856 kb on - strand, within Rv0465c at 555.856 kb on - strand, within Rv0465c at 555.861 kb on + strand, within Rv0465c at 555.861 kb on + strand, within Rv0465c at 555.861 kb on + strand, within Rv0465c at 555.862 kb on - strand, within Rv0465c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM remove 554,085 + Rv0463 0.23 -0.4 554,085 + Rv0463 0.23 +0.1 554,085 + Rv0463 0.23 -0.5 554,086 - Rv0463 0.24 -0.1 554,159 - Rv0463 0.49 +2.2 554,159 - Rv0463 0.49 -0.3 554,301 + +0.1 554,314 + -2.4 554,315 - +0.5 554,315 - -0.1 554,487 + Rv0464c 0.30 -0.9 554,584 - Rv0464c 0.47 -0.8 554,641 - Rv0464c 0.57 -1.9 554,713 + Rv0464c 0.70 -0.4 554,713 + Rv0464c 0.70 -1.2 554,737 + Rv0464c 0.74 -0.6 554,737 + Rv0464c 0.74 -0.7 554,738 - Rv0464c 0.74 -1.8 554,885 + -1.9 554,885 + -1.5 554,886 - -0.4 554,886 - -0.6 555,011 - +1.6 555,026 - Rv0465c 0.10 -0.3 555,026 - Rv0465c 0.10 -0.4 555,061 - Rv0465c 0.13 -0.5 555,116 - Rv0465c 0.16 -0.1 555,129 + Rv0465c 0.17 -0.3 555,171 + Rv0465c 0.20 -0.4 555,371 + Rv0465c 0.34 +0.1 555,371 + Rv0465c 0.34 -0.5 555,372 - Rv0465c 0.34 +0.6 555,372 - Rv0465c 0.34 -0.2 555,372 - Rv0465c 0.34 -0.3 555,403 - Rv0465c 0.37 +0.0 555,414 + Rv0465c 0.37 -0.2 555,415 - Rv0465c 0.37 -0.7 555,505 - Rv0465c 0.44 -0.4 555,505 - Rv0465c 0.44 -0.0 555,505 - Rv0465c 0.44 -0.7 555,508 + Rv0465c 0.44 -0.7 555,509 - Rv0465c 0.44 -0.1 555,600 + Rv0465c 0.50 -0.6 555,601 - Rv0465c 0.50 +0.3 555,731 + Rv0465c 0.60 -0.5 555,732 - Rv0465c 0.60 -0.6 555,732 - Rv0465c 0.60 +0.1 555,836 + Rv0465c 0.67 +1.6 555,837 - Rv0465c 0.67 +0.2 555,837 - Rv0465c 0.67 -2.8 555,837 - Rv0465c 0.67 +2.3 555,837 - Rv0465c 0.67 -0.9 555,840 + Rv0465c 0.67 +0.2 555,855 + Rv0465c 0.68 +1.6 555,855 + Rv0465c 0.68 -0.7 555,855 + Rv0465c 0.68 +0.4 555,855 + Rv0465c 0.68 -0.3 555,856 - Rv0465c 0.68 -0.0 555,856 - Rv0465c 0.68 -3.1 555,861 + Rv0465c 0.69 -0.7 555,861 + Rv0465c 0.69 -0.1 555,861 + Rv0465c 0.69 -1.3 555,862 - Rv0465c 0.69 -1.7
Or see this region's nucleotide sequence