Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1703c

Experiment: 7H9 with Novobiocin 0.004 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1702c and Rv1703c are separated by 555 nucleotidesRv1703c and Rv1704c are separated by 64 nucleotides Rv1702c: Rv1702c - Conserved hypothetical protein, at 1,927,211 to 1,928,575 Rv1702c Rv1703c: Rv1703c - Probable catechol-O-methyltransferase, at 1,929,131 to 1,929,721 Rv1703c Rv1704c: Rv1704c - Probable D-serine/alanine/glycine transporter protein CycA, at 1,929,786 to 1,931,456 Rv1704c Position (kb) 1929 1930Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1928.154 kb on - strand, within Rv1702cat 1928.354 kb on + strand, within Rv1702cat 1928.354 kb on + strand, within Rv1702cat 1928.354 kb on + strand, within Rv1702cat 1928.355 kb on - strand, within Rv1702cat 1928.915 kb on + strandat 1928.915 kb on + strandat 1928.916 kb on - strandat 1929.029 kb on + strandat 1929.029 kb on + strandat 1929.030 kb on - strandat 1929.030 kb on - strandat 1929.141 kb on + strandat 1929.238 kb on + strand, within Rv1703cat 1929.238 kb on + strand, within Rv1703cat 1929.238 kb on + strand, within Rv1703cat 1929.238 kb on + strand, within Rv1703cat 1929.239 kb on - strand, within Rv1703cat 1929.239 kb on - strand, within Rv1703cat 1929.240 kb on + strand, within Rv1703cat 1929.240 kb on + strand, within Rv1703cat 1929.240 kb on + strand, within Rv1703cat 1929.240 kb on + strand, within Rv1703cat 1929.241 kb on - strand, within Rv1703cat 1929.320 kb on + strand, within Rv1703cat 1929.410 kb on + strand, within Rv1703cat 1929.537 kb on + strand, within Rv1703cat 1929.591 kb on + strand, within Rv1703cat 1929.591 kb on + strand, within Rv1703cat 1929.694 kb on - strandat 1929.759 kb on + strandat 1929.759 kb on + strandat 1929.760 kb on - strandat 1929.811 kb on + strandat 1929.812 kb on - strandat 1929.812 kb on - strandat 1930.163 kb on + strand, within Rv1704cat 1930.164 kb on - strand, within Rv1704cat 1930.164 kb on - strand, within Rv1704cat 1930.164 kb on - strand, within Rv1704cat 1930.164 kb on - strand, within Rv1704cat 1930.164 kb on - strand, within Rv1704cat 1930.235 kb on - strand, within Rv1704cat 1930.282 kb on + strand, within Rv1704cat 1930.376 kb on - strand, within Rv1704cat 1930.685 kb on - strand, within Rv1704cat 1930.685 kb on - strand, within Rv1704cat 1930.685 kb on - strand, within Rv1704c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Novobiocin 0.004 mM
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1,928,154 - Rv1702c 0.69 -0.3
1,928,354 + Rv1702c 0.84 -0.1
1,928,354 + Rv1702c 0.84 +0.1
1,928,354 + Rv1702c 0.84 +0.3
1,928,355 - Rv1702c 0.84 -0.6
1,928,915 + -0.6
1,928,915 + -1.1
1,928,916 - -2.1
1,929,029 + +0.2
1,929,029 + +2.9
1,929,030 - -0.1
1,929,030 - -0.2
1,929,141 + -0.5
1,929,238 + Rv1703c 0.18 -0.4
1,929,238 + Rv1703c 0.18 +0.1
1,929,238 + Rv1703c 0.18 +0.7
1,929,238 + Rv1703c 0.18 -0.1
1,929,239 - Rv1703c 0.18 +0.6
1,929,239 - Rv1703c 0.18 -0.4
1,929,240 + Rv1703c 0.18 -0.1
1,929,240 + Rv1703c 0.18 +0.4
1,929,240 + Rv1703c 0.18 +0.2
1,929,240 + Rv1703c 0.18 -1.1
1,929,241 - Rv1703c 0.19 -0.7
1,929,320 + Rv1703c 0.32 +0.1
1,929,410 + Rv1703c 0.47 +0.1
1,929,537 + Rv1703c 0.69 -0.2
1,929,591 + Rv1703c 0.78 -0.2
1,929,591 + Rv1703c 0.78 +1.6
1,929,694 - -1.1
1,929,759 + -0.1
1,929,759 + +0.3
1,929,760 - -0.0
1,929,811 + -0.4
1,929,812 - -0.4
1,929,812 - -1.6
1,930,163 + Rv1704c 0.23 +0.4
1,930,164 - Rv1704c 0.23 -0.0
1,930,164 - Rv1704c 0.23 -0.8
1,930,164 - Rv1704c 0.23 -0.8
1,930,164 - Rv1704c 0.23 +0.6
1,930,164 - Rv1704c 0.23 -2.2
1,930,235 - Rv1704c 0.27 -0.1
1,930,282 + Rv1704c 0.30 -0.1
1,930,376 - Rv1704c 0.35 +0.0
1,930,685 - Rv1704c 0.54 -0.6
1,930,685 - Rv1704c 0.54 +0.5
1,930,685 - Rv1704c 0.54 -0.9

Or see this region's nucleotide sequence