Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0861c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0860 and Rv0861c are separated by 67 nucleotidesRv0861c and Rv0862c are separated by 190 nucleotides Rv0860: Rv0860 - Probable fatty oxidation protein FadB, at 956,293 to 958,455 Rv0860 Rv0861c: Rv0861c - DNA helicase Ercc3, at 958,523 to 960,151 Rv0861c Rv0862c: Rv0862c - Conserved protein, at 960,342 to 962,612 Rv0862c Position (kb) 958 959 960 961Strain fitness (log2 ratio) -2 -1 0 1 2at 958.469 kb on + strandat 958.506 kb on - strandat 958.566 kb on + strandat 958.611 kb on + strandat 958.612 kb on - strandat 958.921 kb on - strand, within Rv0861cat 958.921 kb on - strand, within Rv0861cat 959.040 kb on + strand, within Rv0861cat 959.364 kb on + strand, within Rv0861cat 959.365 kb on - strand, within Rv0861cat 959.956 kb on - strand, within Rv0861cat 959.956 kb on - strand, within Rv0861cat 960.152 kb on + strandat 960.153 kb on - strandat 960.153 kb on - strandat 960.153 kb on - strandat 960.442 kb on - strandat 960.493 kb on + strandat 960.632 kb on + strand, within Rv0862cat 961.067 kb on - strand, within Rv0862c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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958,469 + -0.2
958,506 - -0.2
958,566 + -0.5
958,611 + -0.4
958,612 - -2.5
958,921 - Rv0861c 0.24 -0.6
958,921 - Rv0861c 0.24 +0.3
959,040 + Rv0861c 0.32 -1.0
959,364 + Rv0861c 0.52 -0.4
959,365 - Rv0861c 0.52 -0.6
959,956 - Rv0861c 0.88 +1.9
959,956 - Rv0861c 0.88 +1.0
960,152 + -0.1
960,153 - -0.7
960,153 - -0.6
960,153 - -0.9
960,442 - +0.3
960,493 + -0.7
960,632 + Rv0862c 0.13 +1.3
961,067 - Rv0862c 0.32 +1.1

Or see this region's nucleotide sequence