Experiment: 7H9 with Chloramphenicol 0.01 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3878 and Rv3879c are separated by 57 nucleotides Rv3879c and Rv3880c are separated by 416 nucleotides Rv3880c and Rv3881c overlap by 4 nucleotides
Rv3878: Rv3878 - ESX-1 secretion-associated protein EspJ. Conserved alanine rich protein., at 4,356,693 to 4,357,535
Rv3878
Rv3879c: Rv3879c - ESX-1 secretion-associated protein EspK. Alanine and proline rich protein., at 4,357,593 to 4,359,782
Rv3879c
Rv3880c: Rv3880c - ESX-1 secretion-associated protein EspL, at 4,360,199 to 4,360,546
Rv3880c
Rv3881c: Rv3881c - Secreted ESX-1 substrate protein B, EspB. Conserved alanine and glycine rich protein, at 4,360,543 to 4,361,925
Rv3881c
Position (kb)
4357
4358
4359
4360 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 4356.603 kb on - strand at 4356.677 kb on + strand at 4356.677 kb on + strand at 4356.677 kb on + strand at 4356.677 kb on + strand at 4356.677 kb on + strand at 4356.678 kb on - strand at 4356.678 kb on - strand at 4356.678 kb on - strand at 4356.678 kb on - strand at 4356.678 kb on - strand at 4356.678 kb on - strand at 4356.679 kb on + strand at 4356.680 kb on - strand at 4356.680 kb on - strand at 4356.680 kb on - strand at 4356.812 kb on - strand, within Rv3878 at 4356.812 kb on - strand, within Rv3878 at 4356.927 kb on + strand, within Rv3878 at 4356.970 kb on - strand, within Rv3878 at 4356.970 kb on - strand, within Rv3878 at 4356.970 kb on - strand, within Rv3878 at 4357.533 kb on + strand at 4357.534 kb on - strand at 4357.534 kb on - strand at 4357.534 kb on - strand at 4357.534 kb on - strand at 4357.637 kb on - strand at 4357.735 kb on + strand at 4357.735 kb on + strand at 4357.736 kb on - strand at 4357.736 kb on - strand at 4357.736 kb on - strand at 4358.155 kb on + strand, within Rv3879c at 4358.155 kb on + strand, within Rv3879c at 4358.156 kb on - strand, within Rv3879c at 4358.156 kb on - strand, within Rv3879c at 4358.156 kb on - strand, within Rv3879c at 4358.163 kb on - strand, within Rv3879c at 4358.187 kb on + strand, within Rv3879c at 4358.187 kb on + strand, within Rv3879c at 4358.188 kb on - strand, within Rv3879c at 4358.188 kb on - strand, within Rv3879c at 4358.191 kb on + strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.192 kb on - strand, within Rv3879c at 4358.203 kb on + strand, within Rv3879c at 4358.203 kb on + strand, within Rv3879c at 4358.204 kb on - strand, within Rv3879c at 4358.204 kb on - strand, within Rv3879c at 4358.264 kb on - strand, within Rv3879c at 4358.421 kb on - strand, within Rv3879c at 4358.421 kb on - strand, within Rv3879c at 4358.543 kb on + strand, within Rv3879c at 4358.544 kb on - strand, within Rv3879c at 4359.218 kb on + strand, within Rv3879c at 4359.219 kb on - strand, within Rv3879c at 4359.219 kb on - strand, within Rv3879c at 4359.419 kb on + strand, within Rv3879c at 4359.420 kb on - strand, within Rv3879c at 4359.491 kb on + strand, within Rv3879c at 4359.506 kb on + strand, within Rv3879c at 4359.524 kb on - strand, within Rv3879c at 4359.600 kb on + strand at 4359.648 kb on + strand at 4359.649 kb on - strand at 4359.679 kb on + strand at 4359.680 kb on - strand at 4359.754 kb on + strand at 4359.754 kb on + strand at 4359.754 kb on + strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.755 kb on - strand at 4359.774 kb on - strand at 4359.776 kb on + strand at 4359.776 kb on + strand at 4359.777 kb on - strand at 4359.777 kb on - strand at 4359.777 kb on - strand at 4359.777 kb on - strand at 4360.006 kb on + strand at 4360.006 kb on + strand at 4360.007 kb on - strand at 4360.007 kb on - strand at 4360.007 kb on - strand at 4360.011 kb on - strand at 4360.029 kb on + strand at 4360.029 kb on + strand at 4360.039 kb on + strand at 4360.052 kb on - strand at 4360.067 kb on + strand at 4360.118 kb on - strand at 4360.201 kb on - strand at 4360.201 kb on - strand at 4360.275 kb on + strand, within Rv3880c at 4360.275 kb on + strand, within Rv3880c at 4360.276 kb on - strand, within Rv3880c at 4360.475 kb on + strand, within Rv3880c at 4360.557 kb on + strand at 4360.557 kb on + strand at 4360.557 kb on + strand at 4360.557 kb on + strand at 4360.558 kb on - strand at 4360.617 kb on - strand at 4360.744 kb on + strand, within Rv3881c at 4360.744 kb on + strand, within Rv3881c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM remove 4,356,603 - -0.6 4,356,677 + +1.8 4,356,677 + +0.1 4,356,677 + -0.8 4,356,677 + -0.1 4,356,677 + +0.2 4,356,678 - -0.4 4,356,678 - +1.4 4,356,678 - -0.0 4,356,678 - -0.2 4,356,678 - -0.4 4,356,678 - +0.0 4,356,679 + -0.5 4,356,680 - -0.2 4,356,680 - -0.6 4,356,680 - -0.1 4,356,812 - Rv3878 0.14 -0.3 4,356,812 - Rv3878 0.14 -0.1 4,356,927 + Rv3878 0.28 +2.8 4,356,970 - Rv3878 0.33 +0.4 4,356,970 - Rv3878 0.33 +0.2 4,356,970 - Rv3878 0.33 -0.4 4,357,533 + +0.1 4,357,534 - +0.2 4,357,534 - -0.8 4,357,534 - -0.5 4,357,534 - -0.1 4,357,637 - +0.2 4,357,735 + +1.0 4,357,735 + +0.3 4,357,736 - -0.1 4,357,736 - +0.2 4,357,736 - -0.2 4,358,155 + Rv3879c 0.26 -0.3 4,358,155 + Rv3879c 0.26 -0.4 4,358,156 - Rv3879c 0.26 +0.8 4,358,156 - Rv3879c 0.26 -0.7 4,358,156 - Rv3879c 0.26 -0.6 4,358,163 - Rv3879c 0.26 -0.7 4,358,187 + Rv3879c 0.27 -0.2 4,358,187 + Rv3879c 0.27 +1.8 4,358,188 - Rv3879c 0.27 +0.2 4,358,188 - Rv3879c 0.27 -0.2 4,358,191 + Rv3879c 0.27 -0.4 4,358,192 - Rv3879c 0.27 -2.5 4,358,192 - Rv3879c 0.27 -0.5 4,358,192 - Rv3879c 0.27 -0.1 4,358,192 - Rv3879c 0.27 -0.6 4,358,192 - Rv3879c 0.27 -1.5 4,358,192 - Rv3879c 0.27 -0.9 4,358,192 - Rv3879c 0.27 -0.8 4,358,192 - Rv3879c 0.27 +2.0 4,358,203 + Rv3879c 0.28 -0.6 4,358,203 + Rv3879c 0.28 -2.0 4,358,204 - Rv3879c 0.28 -0.4 4,358,204 - Rv3879c 0.28 -1.1 4,358,264 - Rv3879c 0.31 -0.3 4,358,421 - Rv3879c 0.38 -0.3 4,358,421 - Rv3879c 0.38 -0.6 4,358,543 + Rv3879c 0.43 +0.4 4,358,544 - Rv3879c 0.43 +0.0 4,359,218 + Rv3879c 0.74 +0.3 4,359,219 - Rv3879c 0.74 -1.0 4,359,219 - Rv3879c 0.74 -0.6 4,359,419 + Rv3879c 0.83 -0.1 4,359,420 - Rv3879c 0.83 -0.4 4,359,491 + Rv3879c 0.87 -1.7 4,359,506 + Rv3879c 0.87 -1.4 4,359,524 - Rv3879c 0.88 +0.2 4,359,600 + +0.3 4,359,648 + -0.2 4,359,649 - +1.6 4,359,679 + -0.2 4,359,680 - +0.8 4,359,754 + -0.1 4,359,754 + +0.5 4,359,754 + +0.6 4,359,755 - -0.2 4,359,755 - -1.2 4,359,755 - -0.6 4,359,755 - +0.2 4,359,755 - +0.9 4,359,755 - -0.4 4,359,755 - +0.5 4,359,774 - -0.6 4,359,776 + -0.1 4,359,776 + -0.2 4,359,777 - -0.3 4,359,777 - +0.2 4,359,777 - -0.1 4,359,777 - -0.3 4,360,006 + +0.1 4,360,006 + -0.4 4,360,007 - +0.9 4,360,007 - -1.4 4,360,007 - -0.1 4,360,011 - +0.0 4,360,029 + +0.2 4,360,029 + +1.4 4,360,039 + +0.3 4,360,052 - +1.1 4,360,067 + +0.9 4,360,118 - +0.3 4,360,201 - -0.3 4,360,201 - +0.2 4,360,275 + Rv3880c 0.22 -0.0 4,360,275 + Rv3880c 0.22 +1.8 4,360,276 - Rv3880c 0.22 -0.5 4,360,475 + Rv3880c 0.79 -0.4 4,360,557 + +1.8 4,360,557 + -0.5 4,360,557 + +0.3 4,360,557 + -0.5 4,360,558 - +0.4 4,360,617 - -0.2 4,360,744 + Rv3881c 0.15 +0.4 4,360,744 + Rv3881c 0.15 -2.9
Or see this region's nucleotide sequence