Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3832c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3830c and Rv3831 are separated by 71 nucleotidesRv3831 and Rv3832c overlap by 4 nucleotidesRv3832c and Rv3833 are separated by 55 nucleotidesRv3833 and Rv3834c overlap by 4 nucleotides Rv3830c: Rv3830c - Transcriptional regulatory protein (probably TetR-family), at 4,305,056 to 4,305,685 Rv3830c Rv3831: Rv3831 - Hypothetical protein, at 4,305,757 to 4,306,239 Rv3831 Rv3832c: Rv3832c - Conserved protein, at 4,306,236 to 4,306,811 Rv3832c Rv3833: Rv3833 - Transcriptional regulatory protein (probably AraC-family), at 4,306,867 to 4,307,658 Rv3833 Rv3834c: Rv3834c - SERYL-tRNA synthetase SerS (serine--tRNA ligase) (SERRS) (serine translase), at 4,307,655 to 4,308,914 Rv3834c Position (kb) 4306 4307Strain fitness (log2 ratio) -1 0 1 2 3 4at 4305.323 kb on - strand, within Rv3830cat 4305.376 kb on - strand, within Rv3830cat 4305.537 kb on + strand, within Rv3830cat 4305.880 kb on + strand, within Rv3831at 4305.881 kb on - strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.884 kb on - strand, within Rv3831at 4305.884 kb on - strand, within Rv3831at 4305.997 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.049 kb on - strand, within Rv3831at 4306.049 kb on - strand, within Rv3831at 4306.130 kb on - strand, within Rv3831at 4306.177 kb on + strand, within Rv3831at 4306.298 kb on + strand, within Rv3832cat 4306.299 kb on - strand, within Rv3832cat 4306.299 kb on - strand, within Rv3832cat 4306.358 kb on - strand, within Rv3832cat 4306.358 kb on - strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.377 kb on + strand, within Rv3832cat 4306.459 kb on - strand, within Rv3832cat 4306.794 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.825 kb on - strandat 4306.825 kb on - strandat 4306.825 kb on - strandat 4306.828 kb on + strandat 4306.863 kb on + strandat 4307.099 kb on + strand, within Rv3833at 4307.433 kb on + strand, within Rv3833at 4307.434 kb on - strand, within Rv3833at 4307.434 kb on - strand, within Rv3833at 4307.563 kb on + strand, within Rv3833at 4307.601 kb on + strandat 4307.601 kb on + strandat 4307.602 kb on - strandat 4307.657 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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4,305,323 - Rv3830c 0.42 -0.1
4,305,376 - Rv3830c 0.51 -0.4
4,305,537 + Rv3830c 0.76 -0.3
4,305,880 + Rv3831 0.25 -1.4
4,305,881 - Rv3831 0.26 -0.8
4,305,883 + Rv3831 0.26 +3.8
4,305,883 + Rv3831 0.26 -0.1
4,305,883 + Rv3831 0.26 +0.1
4,305,884 - Rv3831 0.26 +4.2
4,305,884 - Rv3831 0.26 -0.3
4,305,997 + Rv3831 0.50 +0.9
4,306,048 + Rv3831 0.60 -0.1
4,306,048 + Rv3831 0.60 +0.1
4,306,048 + Rv3831 0.60 -0.0
4,306,049 - Rv3831 0.60 +4.1
4,306,049 - Rv3831 0.60 -0.2
4,306,130 - Rv3831 0.77 -0.1
4,306,177 + Rv3831 0.87 -0.2
4,306,298 + Rv3832c 0.11 -0.8
4,306,299 - Rv3832c 0.11 +0.1
4,306,299 - Rv3832c 0.11 -0.4
4,306,358 - Rv3832c 0.21 +1.1
4,306,358 - Rv3832c 0.21 -0.7
4,306,374 + Rv3832c 0.24 +2.3
4,306,374 + Rv3832c 0.24 +0.7
4,306,374 + Rv3832c 0.24 +0.4
4,306,374 + Rv3832c 0.24 +1.8
4,306,374 + Rv3832c 0.24 -1.5
4,306,375 - Rv3832c 0.24 +0.5
4,306,375 - Rv3832c 0.24 -1.4
4,306,375 - Rv3832c 0.24 -1.0
4,306,377 + Rv3832c 0.24 +0.6
4,306,459 - Rv3832c 0.39 -0.2
4,306,794 + +0.2
4,306,824 + -0.2
4,306,824 + -0.5
4,306,824 + -0.5
4,306,824 + -0.1
4,306,824 + +0.1
4,306,824 + -1.3
4,306,825 - -0.0
4,306,825 - +0.8
4,306,825 - -0.6
4,306,828 + -0.0
4,306,863 + -0.9
4,307,099 + Rv3833 0.29 -0.6
4,307,433 + Rv3833 0.71 -1.4
4,307,434 - Rv3833 0.72 -0.3
4,307,434 - Rv3833 0.72 -0.0
4,307,563 + Rv3833 0.88 -0.3
4,307,601 + +0.7
4,307,601 + +0.5
4,307,602 - +1.8
4,307,657 - -0.6

Or see this region's nucleotide sequence