Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2564

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2563 and Rv2564 are separated by 2 nucleotidesRv2564 and Rv2565 are separated by 276 nucleotides Rv2563: Rv2563 - Probable glutamine-transport transmembrane protein ABC transporter, at 2,882,290 to 2,883,339 Rv2563 Rv2564: Rv2564 - Probable glutamine-transport ATP-binding protein ABC transporter GlnQ, at 2,883,342 to 2,884,334 Rv2564 Rv2565: Rv2565 - Conserved protein, at 2,884,611 to 2,886,362 Rv2565 Position (kb) 2883 2884 2885Strain fitness (log2 ratio) -1 0 1 2at 2882.831 kb on + strand, within Rv2563at 2882.831 kb on + strand, within Rv2563at 2882.831 kb on + strand, within Rv2563at 2882.846 kb on - strand, within Rv2563at 2883.040 kb on + strand, within Rv2563at 2883.041 kb on - strand, within Rv2563at 2883.041 kb on - strand, within Rv2563at 2883.320 kb on + strandat 2883.352 kb on + strandat 2883.379 kb on - strandat 2883.379 kb on - strandat 2883.586 kb on - strand, within Rv2564at 2883.601 kb on + strand, within Rv2564at 2883.601 kb on + strand, within Rv2564at 2883.602 kb on - strand, within Rv2564at 2883.602 kb on - strand, within Rv2564at 2883.642 kb on - strand, within Rv2564at 2883.642 kb on - strand, within Rv2564at 2883.705 kb on - strand, within Rv2564at 2883.908 kb on - strand, within Rv2564at 2884.084 kb on - strand, within Rv2564at 2884.254 kb on - strandat 2884.333 kb on - strandat 2884.565 kb on - strandat 2884.729 kb on + strandat 2884.730 kb on - strandat 2884.795 kb on - strand, within Rv2565at 2884.795 kb on - strand, within Rv2565at 2884.843 kb on + strand, within Rv2565at 2884.967 kb on + strand, within Rv2565at 2885.133 kb on - strand, within Rv2565at 2885.313 kb on + strand, within Rv2565at 2885.313 kb on + strand, within Rv2565at 2885.314 kb on - strand, within Rv2565at 2885.314 kb on - strand, within Rv2565at 2885.314 kb on - strand, within Rv2565

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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2,882,831 + Rv2563 0.52 -0.2
2,882,831 + Rv2563 0.52 +0.1
2,882,831 + Rv2563 0.52 +0.3
2,882,846 - Rv2563 0.53 +1.1
2,883,040 + Rv2563 0.71 +0.8
2,883,041 - Rv2563 0.72 +0.6
2,883,041 - Rv2563 0.72 +0.9
2,883,320 + +0.9
2,883,352 + -0.2
2,883,379 - +0.2
2,883,379 - -0.3
2,883,586 - Rv2564 0.25 -0.0
2,883,601 + Rv2564 0.26 +2.7
2,883,601 + Rv2564 0.26 +0.5
2,883,602 - Rv2564 0.26 -0.3
2,883,602 - Rv2564 0.26 +0.8
2,883,642 - Rv2564 0.30 +0.9
2,883,642 - Rv2564 0.30 +1.5
2,883,705 - Rv2564 0.37 +0.7
2,883,908 - Rv2564 0.57 -0.2
2,884,084 - Rv2564 0.75 +0.6
2,884,254 - -0.3
2,884,333 - +0.1
2,884,565 - -0.3
2,884,729 + +0.7
2,884,730 - -0.0
2,884,795 - Rv2565 0.11 -1.0
2,884,795 - Rv2565 0.11 +0.2
2,884,843 + Rv2565 0.13 -0.3
2,884,967 + Rv2565 0.20 -0.7
2,885,133 - Rv2565 0.30 -0.8
2,885,313 + Rv2565 0.40 +0.7
2,885,313 + Rv2565 0.40 -0.6
2,885,314 - Rv2565 0.40 -0.6
2,885,314 - Rv2565 0.40 -0.5
2,885,314 - Rv2565 0.40 -0.1

Or see this region's nucleotide sequence