Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2517c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2515c and Rv2516c are separated by 118 nucleotidesRv2516c and Rv2517c overlap by 4 nucleotidesRv2517c and Rv2518c are separated by 347 nucleotides Rv2515c: Rv2515c - Conserved hypothetical protein, at 2,831,344 to 2,832,591 Rv2515c Rv2516c: Rv2516c - Hypothetical protein, at 2,832,710 to 2,833,513 Rv2516c Rv2517c: Rv2517c - Unknown protein, at 2,833,510 to 2,833,761 Rv2517c Rv2518c: Rv2518c - Probable L,D-transpeptidase LdtB, at 2,834,109 to 2,835,335 Rv2518c Position (kb) 2833 2834Strain fitness (log2 ratio) -1 0 1at 2833.629 kb on + strand, within Rv2517cat 2833.630 kb on - strand, within Rv2517cat 2833.655 kb on + strand, within Rv2517cat 2833.673 kb on + strand, within Rv2517cat 2833.674 kb on - strand, within Rv2517cat 2833.674 kb on - strand, within Rv2517cat 2833.674 kb on - strand, within Rv2517cat 2834.068 kb on + strandat 2834.069 kb on - strandat 2834.110 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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2,833,629 + Rv2517c 0.47 -1.5
2,833,630 - Rv2517c 0.48 -0.6
2,833,655 + Rv2517c 0.58 -0.5
2,833,673 + Rv2517c 0.65 -0.6
2,833,674 - Rv2517c 0.65 -1.0
2,833,674 - Rv2517c 0.65 -0.9
2,833,674 - Rv2517c 0.65 -0.9
2,834,068 + -0.4
2,834,069 - +0.2
2,834,110 + +0.1

Or see this region's nucleotide sequence