Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2426c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2425c and Rv2426c overlap by 1 nucleotidesRv2426c and Rv2427c are separated by 46 nucleotides Rv2425c: Rv2425c - Conserved hypothetical protein, at 2,721,866 to 2,723,308 Rv2425c Rv2426c: Rv2426c - Conserved hypothetical protein, at 2,723,308 to 2,724,183 Rv2426c Rv2427c: Rv2427c - Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase), at 2,724,230 to 2,725,477 Rv2427c Position (kb) 2723 2724 2725Strain fitness (log2 ratio) -1 0 1 2at 2722.317 kb on - strand, within Rv2425cat 2722.317 kb on - strand, within Rv2425cat 2722.621 kb on - strand, within Rv2425cat 2722.864 kb on - strand, within Rv2425cat 2722.864 kb on - strand, within Rv2425cat 2722.872 kb on + strand, within Rv2425cat 2722.969 kb on + strand, within Rv2425cat 2723.083 kb on - strand, within Rv2425cat 2723.087 kb on - strand, within Rv2425cat 2723.294 kb on - strandat 2723.309 kb on + strandat 2723.309 kb on + strandat 2723.309 kb on + strandat 2723.469 kb on + strand, within Rv2426cat 2723.469 kb on + strand, within Rv2426cat 2723.506 kb on + strand, within Rv2426cat 2723.507 kb on - strand, within Rv2426cat 2723.507 kb on - strand, within Rv2426cat 2723.597 kb on + strand, within Rv2426cat 2723.907 kb on + strand, within Rv2426cat 2723.925 kb on - strand, within Rv2426cat 2723.925 kb on - strand, within Rv2426cat 2723.925 kb on - strand, within Rv2426cat 2723.954 kb on + strand, within Rv2426cat 2724.218 kb on + strandat 2724.218 kb on + strandat 2724.587 kb on + strand, within Rv2427cat 2724.756 kb on + strand, within Rv2427cat 2724.756 kb on + strand, within Rv2427cat 2724.757 kb on - strand, within Rv2427cat 2724.963 kb on - strand, within Rv2427cat 2725.147 kb on + strand, within Rv2427cat 2725.147 kb on + strand, within Rv2427cat 2725.148 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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2,722,317 - Rv2425c 0.31 -0.7
2,722,317 - Rv2425c 0.31 -0.1
2,722,621 - Rv2425c 0.52 -0.6
2,722,864 - Rv2425c 0.69 -0.8
2,722,864 - Rv2425c 0.69 +0.1
2,722,872 + Rv2425c 0.70 -0.6
2,722,969 + Rv2425c 0.76 -0.3
2,723,083 - Rv2425c 0.84 -0.6
2,723,087 - Rv2425c 0.85 +1.1
2,723,294 - +0.2
2,723,309 + -0.5
2,723,309 + -1.1
2,723,309 + -0.6
2,723,469 + Rv2426c 0.18 +1.7
2,723,469 + Rv2426c 0.18 +0.7
2,723,506 + Rv2426c 0.23 +1.6
2,723,507 - Rv2426c 0.23 -0.8
2,723,507 - Rv2426c 0.23 -0.3
2,723,597 + Rv2426c 0.33 +0.2
2,723,907 + Rv2426c 0.68 -0.2
2,723,925 - Rv2426c 0.70 -0.0
2,723,925 - Rv2426c 0.70 -0.6
2,723,925 - Rv2426c 0.70 +1.2
2,723,954 + Rv2426c 0.74 +0.8
2,724,218 + +0.5
2,724,218 + -0.2
2,724,587 + Rv2427c 0.29 +0.7
2,724,756 + Rv2427c 0.42 -0.1
2,724,756 + Rv2427c 0.42 +0.6
2,724,757 - Rv2427c 0.42 -0.1
2,724,963 - Rv2427c 0.59 -0.2
2,725,147 + Rv2427c 0.73 +0.0
2,725,147 + Rv2427c 0.73 +2.7
2,725,148 - Rv2427c 0.74 -0.4
2,725,150 - Rv2427c 0.74 +1.7
2,725,150 - Rv2427c 0.74 -0.8
2,725,150 - Rv2427c 0.74 +0.7

Or see this region's nucleotide sequence