Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1968

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1967 and Rv1968 overlap by 4 nucleotidesRv1968 and Rv1969 overlap by 4 nucleotides Rv1967: Rv1967 - Mce-family protein Mce3B, at 2,210,601 to 2,211,629 Rv1967 Rv1968: Rv1968 - Mce-family protein Mce3C, at 2,211,626 to 2,212,858 Rv1968 Rv1969: Rv1969 - Mce-family protein Mce3D, at 2,212,855 to 2,214,126 Rv1969 Position (kb) 2211 2212 2213Strain fitness (log2 ratio) -1 0 1at 2210.653 kb on + strandat 2210.654 kb on - strandat 2210.721 kb on + strand, within Rv1967at 2210.722 kb on - strand, within Rv1967at 2210.724 kb on + strand, within Rv1967at 2210.724 kb on + strand, within Rv1967at 2210.725 kb on - strand, within Rv1967at 2210.725 kb on - strand, within Rv1967at 2211.272 kb on - strand, within Rv1967at 2211.447 kb on + strand, within Rv1967at 2211.447 kb on + strand, within Rv1967at 2211.447 kb on + strand, within Rv1967at 2211.448 kb on - strand, within Rv1967at 2211.483 kb on + strand, within Rv1967at 2211.483 kb on + strand, within Rv1967at 2211.511 kb on - strand, within Rv1967at 2211.511 kb on - strand, within Rv1967at 2211.531 kb on + strandat 2211.583 kb on - strandat 2211.583 kb on - strandat 2211.713 kb on + strandat 2212.019 kb on + strand, within Rv1968at 2212.124 kb on - strand, within Rv1968at 2212.544 kb on + strand, within Rv1968at 2212.544 kb on + strand, within Rv1968at 2212.544 kb on + strand, within Rv1968at 2212.545 kb on - strand, within Rv1968at 2212.545 kb on - strand, within Rv1968at 2213.102 kb on - strand, within Rv1969at 2213.102 kb on - strand, within Rv1969at 2213.216 kb on + strand, within Rv1969at 2213.217 kb on - strand, within Rv1969

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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2,210,653 + -0.7
2,210,654 - -0.1
2,210,721 + Rv1967 0.12 -0.0
2,210,722 - Rv1967 0.12 +1.7
2,210,724 + Rv1967 0.12 +0.6
2,210,724 + Rv1967 0.12 -0.5
2,210,725 - Rv1967 0.12 -0.7
2,210,725 - Rv1967 0.12 -0.3
2,211,272 - Rv1967 0.65 -0.6
2,211,447 + Rv1967 0.82 +0.7
2,211,447 + Rv1967 0.82 +1.7
2,211,447 + Rv1967 0.82 +0.6
2,211,448 - Rv1967 0.82 +0.0
2,211,483 + Rv1967 0.86 -0.6
2,211,483 + Rv1967 0.86 +1.0
2,211,511 - Rv1967 0.88 +0.1
2,211,511 - Rv1967 0.88 -0.4
2,211,531 + -0.3
2,211,583 - +0.4
2,211,583 - -0.3
2,211,713 + -0.4
2,212,019 + Rv1968 0.32 +0.3
2,212,124 - Rv1968 0.40 +1.0
2,212,544 + Rv1968 0.74 -0.2
2,212,544 + Rv1968 0.74 -0.2
2,212,544 + Rv1968 0.74 +0.2
2,212,545 - Rv1968 0.75 +0.6
2,212,545 - Rv1968 0.75 +0.5
2,213,102 - Rv1969 0.19 -0.6
2,213,102 - Rv1969 0.19 -0.9
2,213,216 + Rv1969 0.28 -0.1
2,213,217 - Rv1969 0.28 +0.1

Or see this region's nucleotide sequence