Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1737c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1736c and Rv1737c overlap by 4 nucleotidesRv1737c and Rv1738 are separated by 286 nucleotidesRv1738 and Rv1739c are separated by 13 nucleotides Rv1736c: Rv1736c - Probable nitrate reductase NarX, at 1,962,228 to 1,964,186 Rv1736c Rv1737c: Rv1737c - Possible nitrate/nitrite transporter NarK2, at 1,964,183 to 1,965,370 Rv1737c Rv1738: Rv1738 - Conserved protein, at 1,965,657 to 1,965,941 Rv1738 Rv1739c: Rv1739c - Probable sulphate-transport transmembrane protein ABC transporter, at 1,965,955 to 1,967,637 Rv1739c Position (kb) 1964 1965 1966Strain fitness (log2 ratio) -1 0 1 2 3at 1963.207 kb on + strand, within Rv1736cat 1963.207 kb on + strand, within Rv1736cat 1963.207 kb on + strand, within Rv1736cat 1963.505 kb on - strand, within Rv1736cat 1963.792 kb on + strand, within Rv1736cat 1963.847 kb on - strand, within Rv1736cat 1963.847 kb on - strand, within Rv1736cat 1963.847 kb on - strand, within Rv1736cat 1963.847 kb on - strand, within Rv1736cat 1963.895 kb on - strand, within Rv1736cat 1963.970 kb on - strand, within Rv1736cat 1964.232 kb on + strandat 1964.232 kb on + strandat 1964.283 kb on + strandat 1964.335 kb on - strand, within Rv1737cat 1964.676 kb on + strand, within Rv1737cat 1964.676 kb on + strand, within Rv1737cat 1964.676 kb on + strand, within Rv1737cat 1964.677 kb on - strand, within Rv1737cat 1964.677 kb on - strand, within Rv1737cat 1964.688 kb on + strand, within Rv1737cat 1964.688 kb on + strand, within Rv1737cat 1964.689 kb on - strand, within Rv1737cat 1964.956 kb on + strand, within Rv1737cat 1965.081 kb on + strand, within Rv1737cat 1965.277 kb on - strandat 1965.584 kb on + strandat 1965.585 kb on - strandat 1965.936 kb on + strandat 1965.937 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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1,963,207 + Rv1736c 0.50 +0.7
1,963,207 + Rv1736c 0.50 -0.5
1,963,207 + Rv1736c 0.50 +2.7
1,963,505 - Rv1736c 0.65 -0.3
1,963,792 + Rv1736c 0.80 +3.3
1,963,847 - Rv1736c 0.83 +0.7
1,963,847 - Rv1736c 0.83 +0.2
1,963,847 - Rv1736c 0.83 -0.0
1,963,847 - Rv1736c 0.83 +0.8
1,963,895 - Rv1736c 0.85 +1.7
1,963,970 - Rv1736c 0.89 +0.1
1,964,232 + -0.1
1,964,232 + +0.4
1,964,283 + +0.7
1,964,335 - Rv1737c 0.13 +0.7
1,964,676 + Rv1737c 0.41 -0.4
1,964,676 + Rv1737c 0.41 -0.1
1,964,676 + Rv1737c 0.41 -0.3
1,964,677 - Rv1737c 0.42 -0.1
1,964,677 - Rv1737c 0.42 -0.5
1,964,688 + Rv1737c 0.43 +0.6
1,964,688 + Rv1737c 0.43 -0.3
1,964,689 - Rv1737c 0.43 -0.3
1,964,956 + Rv1737c 0.65 -0.2
1,965,081 + Rv1737c 0.76 -0.1
1,965,277 - +0.0
1,965,584 + -0.6
1,965,585 - -0.9
1,965,936 + +0.8
1,965,937 - -0.5

Or see this region's nucleotide sequence