Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0585c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0584 and Rv0585c are separated by 22 nucleotidesRv0585c and Rv0586 are separated by 137 nucleotidesRv0586 and Rv0587 overlap by 4 nucleotides Rv0584: Rv0584 - Possible conserved exported protein, at 679,229 to 681,862 Rv0584 Rv0585c: Rv0585c - Probable conserved integral membrane protein, at 681,885 to 684,272 Rv0585c Rv0586: Rv0586 - Probable transcriptional regulatory protein Mce2R (GntR-family), at 684,410 to 685,132 Rv0586 Rv0587: Rv0587 - Conserved hypothetical integral membrane protein YrbE2A, at 685,129 to 685,926 Rv0587 Position (kb) 681 682 683 684 685Strain fitness (log2 ratio) -2 -1 0 1at 680.888 kb on + strand, within Rv0584at 680.939 kb on + strand, within Rv0584at 680.939 kb on + strand, within Rv0584at 681.060 kb on - strand, within Rv0584at 681.060 kb on - strand, within Rv0584at 681.104 kb on + strand, within Rv0584at 681.111 kb on - strand, within Rv0584at 681.111 kb on - strand, within Rv0584at 681.225 kb on - strand, within Rv0584at 681.381 kb on - strand, within Rv0584at 681.558 kb on + strand, within Rv0584at 681.558 kb on + strand, within Rv0584at 681.754 kb on - strandat 681.780 kb on - strandat 681.788 kb on + strandat 681.788 kb on + strandat 681.789 kb on - strandat 681.812 kb on - strandat 681.886 kb on + strandat 682.251 kb on + strand, within Rv0585cat 682.252 kb on - strand, within Rv0585cat 682.386 kb on + strand, within Rv0585cat 682.739 kb on + strand, within Rv0585cat 682.762 kb on + strand, within Rv0585cat 682.780 kb on - strand, within Rv0585cat 683.145 kb on - strand, within Rv0585cat 683.266 kb on + strand, within Rv0585cat 683.266 kb on + strand, within Rv0585cat 683.267 kb on - strand, within Rv0585cat 683.326 kb on - strand, within Rv0585cat 683.326 kb on - strand, within Rv0585cat 683.952 kb on - strand, within Rv0585cat 684.058 kb on + strandat 684.059 kb on - strandat 684.278 kb on - strandat 684.278 kb on - strandat 684.339 kb on + strandat 684.700 kb on + strand, within Rv0586at 685.157 kb on - strandat 685.217 kb on + strand, within Rv0587at 685.218 kb on - strand, within Rv0587

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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680,888 + Rv0584 0.63 +1.7
680,939 + Rv0584 0.65 -0.2
680,939 + Rv0584 0.65 -0.1
681,060 - Rv0584 0.70 -0.5
681,060 - Rv0584 0.70 -0.4
681,104 + Rv0584 0.71 +1.0
681,111 - Rv0584 0.71 -0.8
681,111 - Rv0584 0.71 -2.7
681,225 - Rv0584 0.76 +0.0
681,381 - Rv0584 0.82 -1.7
681,558 + Rv0584 0.88 -0.2
681,558 + Rv0584 0.88 -1.6
681,754 - -0.8
681,780 - +0.1
681,788 + +1.3
681,788 + +0.1
681,789 - -2.0
681,812 - -0.3
681,886 + -0.1
682,251 + Rv0585c 0.15 -0.8
682,252 - Rv0585c 0.15 -1.0
682,386 + Rv0585c 0.21 -1.4
682,739 + Rv0585c 0.36 +0.1
682,762 + Rv0585c 0.37 -1.3
682,780 - Rv0585c 0.37 -0.2
683,145 - Rv0585c 0.53 -0.7
683,266 + Rv0585c 0.58 +0.1
683,266 + Rv0585c 0.58 +0.6
683,267 - Rv0585c 0.58 -0.1
683,326 - Rv0585c 0.60 -0.3
683,326 - Rv0585c 0.60 -1.8
683,952 - Rv0585c 0.87 -1.8
684,058 + +0.3
684,059 - -0.2
684,278 - -0.6
684,278 - -0.5
684,339 + -0.2
684,700 + Rv0586 0.40 -0.4
685,157 - -0.1
685,217 + Rv0587 0.11 +0.1
685,218 - Rv0587 0.11 -0.4

Or see this region's nucleotide sequence