Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0318c

Experiment: 7H9 with Chloramphenicol 0.01 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0317c and GFF329 are separated by 260 nucleotidesGFF329 and Rv0318c are separated by 30 nucleotidesRv0318c and Rv0319 are separated by 48 nucleotidesRv0319 and Rv0320 are separated by 71 nucleotides Rv0317c: Rv0317c - Possible glycerophosphoryl diester phosphodiesterase GlpQ2 (glycerophosphodiester phosphodiesterase), at 385,173 to 385,943 Rv0317c GFF329 - tRNA-Gly, at 386,204 to 386,274 GFF329 Rv0318c: Rv0318c - Probable conserved integral membrane protein, at 386,305 to 387,099 Rv0318c Rv0319: Rv0319 - Probable pyrrolidone-carboxylate peptidase Pcp (5-oxoprolyl-peptidase) (pyroglutamyl-peptidase I) (PGP-I) (pyrase), at 387,148 to 387,816 Rv0319 Rv0320: Rv0320 - Possible conserved exported protein, at 387,888 to 388,550 Rv0320 Position (kb) 386 387 388Strain fitness (log2 ratio) -3 -2 -1 0 1at 385.359 kb on + strand, within Rv0317cat 385.421 kb on - strand, within Rv0317cat 385.421 kb on - strand, within Rv0317cat 385.421 kb on - strand, within Rv0317cat 385.484 kb on + strand, within Rv0317cat 385.617 kb on - strand, within Rv0317cat 385.766 kb on + strand, within Rv0317cat 385.767 kb on - strand, within Rv0317cat 385.788 kb on + strand, within Rv0317cat 385.825 kb on + strand, within Rv0317cat 385.826 kb on - strand, within Rv0317cat 385.983 kb on + strandat 385.983 kb on + strandat 386.075 kb on - strandat 386.294 kb on - strandat 386.327 kb on + strandat 386.328 kb on - strandat 386.466 kb on + strand, within Rv0318cat 386.522 kb on - strand, within Rv0318cat 386.560 kb on - strand, within Rv0318cat 386.714 kb on - strand, within Rv0318cat 386.800 kb on + strand, within Rv0318cat 386.867 kb on - strand, within Rv0318cat 387.134 kb on - strandat 387.490 kb on + strand, within Rv0319at 387.598 kb on + strand, within Rv0319at 387.599 kb on - strand, within Rv0319at 387.599 kb on - strand, within Rv0319at 387.599 kb on - strand, within Rv0319at 387.781 kb on - strandat 387.847 kb on - strandat 387.904 kb on + strandat 387.992 kb on + strand, within Rv0320at 387.992 kb on + strand, within Rv0320at 388.093 kb on + strand, within Rv0320at 388.094 kb on - strand, within Rv0320

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Chloramphenicol 0.01 mM
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385,359 + Rv0317c 0.24 -0.4
385,421 - Rv0317c 0.32 +0.0
385,421 - Rv0317c 0.32 +0.2
385,421 - Rv0317c 0.32 -0.6
385,484 + Rv0317c 0.40 -0.7
385,617 - Rv0317c 0.58 +0.1
385,766 + Rv0317c 0.77 -0.1
385,767 - Rv0317c 0.77 -0.8
385,788 + Rv0317c 0.80 +1.3
385,825 + Rv0317c 0.85 +0.4
385,826 - Rv0317c 0.85 +0.5
385,983 + -0.3
385,983 + -0.8
386,075 - -0.9
386,294 - -0.6
386,327 + -0.6
386,328 - +0.1
386,466 + Rv0318c 0.20 -1.2
386,522 - Rv0318c 0.27 -0.3
386,560 - Rv0318c 0.32 -0.4
386,714 - Rv0318c 0.51 -1.4
386,800 + Rv0318c 0.62 -0.4
386,867 - Rv0318c 0.71 -0.8
387,134 - +0.1
387,490 + Rv0319 0.51 -0.4
387,598 + Rv0319 0.67 -1.0
387,599 - Rv0319 0.67 +1.2
387,599 - Rv0319 0.67 +0.0
387,599 - Rv0319 0.67 -0.0
387,781 - -0.0
387,847 - -0.8
387,904 + -2.9
387,992 + Rv0320 0.16 -0.7
387,992 + Rv0320 0.16 +0.1
388,093 + Rv0320 0.31 -0.0
388,094 - Rv0320 0.31 +0.2

Or see this region's nucleotide sequence