Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2804c

Experiment: 7H9 with Econazole nitrate salt 0.0082 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2802c and Rv2803 overlap by 2 nucleotidesRv2803 and Rv2804c are separated by 175 nucleotidesRv2804c and Rv2805 overlap by 228 nucleotidesRv2805 and Rv2806 overlap by 4 nucleotidesRv2806 and Rv2807 are separated by 198 nucleotides Rv2802c: Rv2802c - Hypothetical arginine and alanine rich protein, at 3,110,780 to 3,111,823 Rv2802c Rv2803: Rv2803 - Conserved hypothetical protein, at 3,111,822 to 3,112,289 Rv2803 Rv2804c: Rv2804c - Hypothetical protein, at 3,112,465 to 3,113,094 Rv2804c Rv2805: Rv2805 - Conserved hypothetical protein, at 3,112,867 to 3,113,271 Rv2805 Rv2806: Rv2806 - Possible membrane protein, at 3,113,268 to 3,113,459 Rv2806 Rv2807: Rv2807 - Conserved hypothetical protein, at 3,113,658 to 3,114,812 Rv2807 Position (kb) 3112 3113 3114Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3111.567 kb on + strand, within Rv2802cat 3111.656 kb on + strand, within Rv2802cat 3111.656 kb on + strand, within Rv2802cat 3111.656 kb on + strand, within Rv2802cat 3111.656 kb on + strand, within Rv2802cat 3111.657 kb on - strand, within Rv2802cat 3111.873 kb on + strand, within Rv2803at 3111.874 kb on - strand, within Rv2803at 3111.996 kb on + strand, within Rv2803at 3111.996 kb on + strand, within Rv2803at 3111.997 kb on - strand, within Rv2803at 3111.997 kb on - strand, within Rv2803at 3111.997 kb on - strand, within Rv2803at 3111.997 kb on - strand, within Rv2803at 3112.002 kb on + strand, within Rv2803at 3112.002 kb on + strand, within Rv2803at 3112.007 kb on + strand, within Rv2803at 3112.007 kb on + strand, within Rv2803at 3112.007 kb on + strand, within Rv2803at 3112.008 kb on - strand, within Rv2803at 3112.008 kb on - strand, within Rv2803at 3112.008 kb on - strand, within Rv2803at 3112.008 kb on - strand, within Rv2803at 3112.008 kb on - strand, within Rv2803at 3112.011 kb on + strand, within Rv2803at 3112.011 kb on + strand, within Rv2803at 3112.012 kb on - strand, within Rv2803at 3112.012 kb on - strand, within Rv2803at 3112.466 kb on + strandat 3112.658 kb on - strand, within Rv2804cat 3112.658 kb on - strand, within Rv2804cat 3112.712 kb on - strand, within Rv2804cat 3112.712 kb on - strand, within Rv2804cat 3112.791 kb on - strand, within Rv2804cat 3112.791 kb on - strand, within Rv2804cat 3112.993 kb on - strandat 3113.077 kb on + strandat 3113.302 kb on - strand, within Rv2806at 3113.341 kb on + strand, within Rv2806at 3113.341 kb on + strand, within Rv2806at 3113.382 kb on - strand, within Rv2806at 3113.409 kb on + strand, within Rv2806at 3113.410 kb on - strand, within Rv2806at 3113.444 kb on + strandat 3113.445 kb on - strandat 3113.589 kb on + strandat 3113.589 kb on + strandat 3113.589 kb on + strandat 3113.589 kb on + strandat 3113.607 kb on - strandat 3113.795 kb on - strand, within Rv2807

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Econazole nitrate salt 0.0082 mM
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3,111,567 + Rv2802c 0.75 +0.5
3,111,656 + Rv2802c 0.84 -2.1
3,111,656 + Rv2802c 0.84 -0.4
3,111,656 + Rv2802c 0.84 +0.5
3,111,656 + Rv2802c 0.84 -0.7
3,111,657 - Rv2802c 0.84 -0.4
3,111,873 + Rv2803 0.11 +0.0
3,111,874 - Rv2803 0.11 +0.1
3,111,996 + Rv2803 0.37 -1.3
3,111,996 + Rv2803 0.37 +3.7
3,111,997 - Rv2803 0.37 -1.8
3,111,997 - Rv2803 0.37 -0.4
3,111,997 - Rv2803 0.37 -0.2
3,111,997 - Rv2803 0.37 -0.6
3,112,002 + Rv2803 0.38 +2.2
3,112,002 + Rv2803 0.38 -0.4
3,112,007 + Rv2803 0.40 -0.4
3,112,007 + Rv2803 0.40 -0.3
3,112,007 + Rv2803 0.40 -0.1
3,112,008 - Rv2803 0.40 +0.3
3,112,008 - Rv2803 0.40 +0.0
3,112,008 - Rv2803 0.40 -0.1
3,112,008 - Rv2803 0.40 +0.5
3,112,008 - Rv2803 0.40 +0.5
3,112,011 + Rv2803 0.40 +0.0
3,112,011 + Rv2803 0.40 -0.4
3,112,012 - Rv2803 0.41 -0.5
3,112,012 - Rv2803 0.41 -0.3
3,112,466 + -0.5
3,112,658 - Rv2804c 0.31 +1.6
3,112,658 - Rv2804c 0.31 -0.0
3,112,712 - Rv2804c 0.39 +0.2
3,112,712 - Rv2804c 0.39 +0.2
3,112,791 - Rv2804c 0.52 +1.5
3,112,791 - Rv2804c 0.52 -0.1
3,112,993 - -0.3
3,113,077 + +1.9
3,113,302 - Rv2806 0.18 -0.5
3,113,341 + Rv2806 0.38 +1.1
3,113,341 + Rv2806 0.38 +0.6
3,113,382 - Rv2806 0.59 -0.1
3,113,409 + Rv2806 0.73 +0.4
3,113,410 - Rv2806 0.74 -0.3
3,113,444 + +0.1
3,113,445 - -0.9
3,113,589 + -1.7
3,113,589 + -0.2
3,113,589 + +0.1
3,113,589 + -0.2
3,113,607 - -0.3
3,113,795 - Rv2807 0.12 -0.5

Or see this region's nucleotide sequence