Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3307

Experiment: 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3306c and Rv3307 are separated by 64 nucleotidesRv3307 and Rv3308 are separated by 3 nucleotides Rv3306c: Rv3306c - Probable amidohydrolase AmiB1 (aminohydrolase), at 3,692,805 to 3,693,989 Rv3306c Rv3307: Rv3307 - Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP), at 3,694,054 to 3,694,860 Rv3307 Rv3308: Rv3308 - Probable phosphomannomutase PmmB (phosphomannose mutase), at 3,694,864 to 3,696,468 Rv3308 Position (kb) 3694 3695Strain fitness (log2 ratio) -2 -1 0 1at 3693.278 kb on - strand, within Rv3306cat 3693.375 kb on + strand, within Rv3306cat 3693.419 kb on + strand, within Rv3306cat 3693.998 kb on + strandat 3694.040 kb on + strandat 3694.268 kb on + strand, within Rv3307at 3694.349 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.396 kb on - strand, within Rv3307at 3694.532 kb on - strand, within Rv3307at 3694.615 kb on + strand, within Rv3307at 3694.615 kb on + strand, within Rv3307at 3694.730 kb on + strand, within Rv3307at 3694.858 kb on + strandat 3695.300 kb on - strand, within Rv3308at 3695.309 kb on - strand, within Rv3308at 3695.452 kb on - strand, within Rv3308at 3695.452 kb on - strand, within Rv3308at 3695.452 kb on - strand, within Rv3308at 3695.578 kb on - strand, within Rv3308

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
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3,693,278 - Rv3306c 0.40 -2.1
3,693,375 + Rv3306c 0.48 -2.6
3,693,419 + Rv3306c 0.52 +0.3
3,693,998 + -0.6
3,694,040 + -0.1
3,694,268 + Rv3307 0.27 -0.1
3,694,349 - Rv3307 0.37 -0.5
3,694,396 - Rv3307 0.42 +0.7
3,694,396 - Rv3307 0.42 +0.9
3,694,396 - Rv3307 0.42 -0.8
3,694,532 - Rv3307 0.59 +1.5
3,694,615 + Rv3307 0.70 -0.6
3,694,615 + Rv3307 0.70 +0.4
3,694,730 + Rv3307 0.84 -0.1
3,694,858 + -1.1
3,695,300 - Rv3308 0.27 +1.7
3,695,309 - Rv3308 0.28 -0.1
3,695,452 - Rv3308 0.37 -0.9
3,695,452 - Rv3308 0.37 +0.0
3,695,452 - Rv3308 0.37 +0.4
3,695,578 - Rv3308 0.44 -0.2

Or see this region's nucleotide sequence