Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0196

Experiment: 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0195 and Rv0196 are separated by 112 nucleotidesRv0196 and Rv0197 overlap by 1 nucleotides Rv0195: Rv0195 - Possible two component transcriptional regulatory protein (probably LuxR-family), at 230,899 to 231,534 Rv0195 Rv0196: Rv0196 - Possible transcriptional regulatory protein, at 231,647 to 232,231 Rv0196 Rv0197: Rv0197 - Possible oxidoreductase, at 232,231 to 234,519 Rv0197 Position (kb) 231 232 233Strain fitness (log2 ratio) -1 0 1 2at 230.709 kb on + strandat 231.071 kb on + strand, within Rv0195at 231.071 kb on + strand, within Rv0195at 231.072 kb on - strand, within Rv0195at 231.196 kb on + strand, within Rv0195at 231.383 kb on + strand, within Rv0195at 231.427 kb on + strand, within Rv0195at 231.428 kb on - strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.464 kb on + strand, within Rv0195at 231.555 kb on + strandat 231.555 kb on + strandat 231.555 kb on + strandat 231.555 kb on + strandat 231.556 kb on - strandat 231.556 kb on - strandat 231.589 kb on + strandat 231.589 kb on + strandat 231.626 kb on + strandat 231.626 kb on + strandat 231.626 kb on + strandat 231.627 kb on - strandat 231.767 kb on + strand, within Rv0196at 231.768 kb on - strand, within Rv0196at 231.768 kb on - strand, within Rv0196at 231.774 kb on - strand, within Rv0196at 231.896 kb on + strand, within Rv0196at 232.071 kb on + strand, within Rv0196at 232.071 kb on + strand, within Rv0196at 232.072 kb on - strand, within Rv0196at 232.360 kb on + strandat 232.393 kb on + strandat 232.541 kb on - strand, within Rv0197at 232.541 kb on - strand, within Rv0197at 232.543 kb on + strand, within Rv0197at 232.543 kb on + strand, within Rv0197at 232.543 kb on + strand, within Rv0197

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
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230,709 + +0.1
231,071 + Rv0195 0.27 -0.0
231,071 + Rv0195 0.27 -0.4
231,072 - Rv0195 0.27 +0.1
231,196 + Rv0195 0.47 +2.6
231,383 + Rv0195 0.76 -0.3
231,427 + Rv0195 0.83 -0.4
231,428 - Rv0195 0.83 +1.6
231,464 + Rv0195 0.89 -0.0
231,464 + Rv0195 0.89 -0.3
231,464 + Rv0195 0.89 -0.1
231,464 + Rv0195 0.89 -0.6
231,464 + Rv0195 0.89 -0.8
231,464 + Rv0195 0.89 +0.0
231,555 + +0.6
231,555 + +0.3
231,555 + -0.8
231,555 + +0.7
231,556 - -0.0
231,556 - -0.0
231,589 + -0.2
231,589 + +0.0
231,626 + +1.4
231,626 + -0.3
231,626 + -1.1
231,627 - +0.6
231,767 + Rv0196 0.21 -0.5
231,768 - Rv0196 0.21 -0.5
231,768 - Rv0196 0.21 -1.4
231,774 - Rv0196 0.22 -0.7
231,896 + Rv0196 0.43 +0.7
232,071 + Rv0196 0.72 -1.7
232,071 + Rv0196 0.72 -1.0
232,072 - Rv0196 0.73 -0.9
232,360 + -0.0
232,393 + +0.4
232,541 - Rv0197 0.14 +0.6
232,541 - Rv0197 0.14 -0.2
232,543 + Rv0197 0.14 +0.3
232,543 + Rv0197 0.14 -1.1
232,543 + Rv0197 0.14 +1.0

Or see this region's nucleotide sequence