Experiment: 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2066 and Rv2067c overlap by 55 nucleotides Rv2067c and Rv2068c are separated by 15 nucleotides
Rv2066: Rv2066 - Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase, at 2,323,175 to 2,324,701
Rv2066
Rv2067c: Rv2067c - Conserved protein, at 2,324,647 to 2,325,870
Rv2067c
Rv2068c: Rv2068c - Class a beta-lactamase BlaC, at 2,325,886 to 2,326,809
Rv2068c
Position (kb)
2324
2325
2326 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2 at 2323.862 kb on + strand, within Rv2066 at 2323.863 kb on - strand, within Rv2066 at 2323.863 kb on - strand, within Rv2066 at 2323.863 kb on - strand, within Rv2066 at 2324.161 kb on - strand, within Rv2066 at 2324.161 kb on - strand, within Rv2066 at 2324.288 kb on + strand, within Rv2066 at 2324.384 kb on + strand, within Rv2066 at 2324.384 kb on + strand, within Rv2066 at 2324.384 kb on + strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.385 kb on - strand, within Rv2066 at 2324.575 kb on - strand at 2324.669 kb on - strand at 2324.669 kb on - strand at 2324.669 kb on - strand at 2324.869 kb on - strand, within Rv2067c at 2324.869 kb on - strand, within Rv2067c at 2324.909 kb on - strand, within Rv2067c at 2324.912 kb on + strand, within Rv2067c at 2324.912 kb on + strand, within Rv2067c at 2324.913 kb on - strand, within Rv2067c at 2324.949 kb on - strand, within Rv2067c at 2324.949 kb on - strand, within Rv2067c at 2325.066 kb on - strand, within Rv2067c at 2325.101 kb on + strand, within Rv2067c at 2325.102 kb on - strand, within Rv2067c at 2325.281 kb on - strand, within Rv2067c at 2325.384 kb on - strand, within Rv2067c at 2325.384 kb on - strand, within Rv2067c at 2325.616 kb on - strand, within Rv2067c at 2325.828 kb on - strand at 2325.887 kb on + strand at 2325.887 kb on + strand at 2325.887 kb on + strand at 2325.992 kb on + strand, within Rv2068c at 2325.992 kb on + strand, within Rv2068c at 2325.993 kb on - strand, within Rv2068c at 2326.224 kb on + strand, within Rv2068c at 2326.311 kb on - strand, within Rv2068c at 2326.311 kb on - strand, within Rv2068c at 2326.387 kb on - strand, within Rv2068c at 2326.387 kb on - strand, within Rv2068c at 2326.388 kb on + strand, within Rv2068c at 2326.388 kb on + strand, within Rv2068c at 2326.389 kb on - strand, within Rv2068c at 2326.393 kb on + strand, within Rv2068c at 2326.393 kb on + strand, within Rv2068c at 2326.484 kb on + strand, within Rv2068c at 2326.484 kb on + strand, within Rv2068c at 2326.485 kb on - strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.625 kb on + strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.626 kb on - strand, within Rv2068c at 2326.646 kb on + strand, within Rv2068c at 2326.646 kb on + strand, within Rv2068c at 2326.647 kb on - strand, within Rv2068c at 2326.647 kb on - strand, within Rv2068c at 2326.647 kb on - strand, within Rv2068c at 2326.814 kb on + strand at 2326.815 kb on - strand at 2326.815 kb on - strand at 2326.815 kb on - strand at 2326.817 kb on + strand at 2326.818 kb on - strand at 2326.818 kb on - strand at 2326.818 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with 2-Mercaptopyridine N-oxide 0.0078 mM remove 2,323,862 + Rv2066 0.45 -0.9 2,323,863 - Rv2066 0.45 -0.8 2,323,863 - Rv2066 0.45 -0.5 2,323,863 - Rv2066 0.45 -0.9 2,324,161 - Rv2066 0.65 +0.0 2,324,161 - Rv2066 0.65 -0.9 2,324,288 + Rv2066 0.73 +0.3 2,324,384 + Rv2066 0.79 -1.0 2,324,384 + Rv2066 0.79 +0.4 2,324,384 + Rv2066 0.79 +1.8 2,324,385 - Rv2066 0.79 +0.0 2,324,385 - Rv2066 0.79 +0.1 2,324,385 - Rv2066 0.79 +0.3 2,324,385 - Rv2066 0.79 +0.8 2,324,385 - Rv2066 0.79 +0.0 2,324,385 - Rv2066 0.79 -0.3 2,324,575 - -1.2 2,324,669 - -0.6 2,324,669 - +0.3 2,324,669 - -0.6 2,324,869 - Rv2067c 0.18 +0.7 2,324,869 - Rv2067c 0.18 +1.2 2,324,909 - Rv2067c 0.21 -0.3 2,324,912 + Rv2067c 0.22 +1.6 2,324,912 + Rv2067c 0.22 -0.2 2,324,913 - Rv2067c 0.22 +1.0 2,324,949 - Rv2067c 0.25 -0.9 2,324,949 - Rv2067c 0.25 +0.7 2,325,066 - Rv2067c 0.34 +1.8 2,325,101 + Rv2067c 0.37 -0.1 2,325,102 - Rv2067c 0.37 -0.7 2,325,281 - Rv2067c 0.52 -0.1 2,325,384 - Rv2067c 0.60 -0.2 2,325,384 - Rv2067c 0.60 -0.4 2,325,616 - Rv2067c 0.79 -0.2 2,325,828 - -1.1 2,325,887 + -0.8 2,325,887 + -0.1 2,325,887 + -0.4 2,325,992 + Rv2068c 0.11 -1.1 2,325,992 + Rv2068c 0.11 -0.0 2,325,993 - Rv2068c 0.12 +0.8 2,326,224 + Rv2068c 0.37 -1.0 2,326,311 - Rv2068c 0.46 +0.2 2,326,311 - Rv2068c 0.46 +1.5 2,326,387 - Rv2068c 0.54 -0.8 2,326,387 - Rv2068c 0.54 -0.6 2,326,388 + Rv2068c 0.54 -2.1 2,326,388 + Rv2068c 0.54 -0.9 2,326,389 - Rv2068c 0.54 -0.0 2,326,393 + Rv2068c 0.55 -1.5 2,326,393 + Rv2068c 0.55 -2.1 2,326,484 + Rv2068c 0.65 -0.1 2,326,484 + Rv2068c 0.65 +0.2 2,326,485 - Rv2068c 0.65 -0.7 2,326,625 + Rv2068c 0.80 +0.3 2,326,625 + Rv2068c 0.80 -1.4 2,326,625 + Rv2068c 0.80 +0.5 2,326,625 + Rv2068c 0.80 +1.8 2,326,625 + Rv2068c 0.80 -0.8 2,326,625 + Rv2068c 0.80 -0.3 2,326,626 - Rv2068c 0.80 +0.1 2,326,626 - Rv2068c 0.80 -1.5 2,326,626 - Rv2068c 0.80 -0.6 2,326,626 - Rv2068c 0.80 -0.0 2,326,626 - Rv2068c 0.80 +0.6 2,326,626 - Rv2068c 0.80 +1.3 2,326,626 - Rv2068c 0.80 -0.0 2,326,626 - Rv2068c 0.80 -0.8 2,326,646 + Rv2068c 0.82 -0.0 2,326,646 + Rv2068c 0.82 +0.8 2,326,647 - Rv2068c 0.82 -4.3 2,326,647 - Rv2068c 0.82 +0.3 2,326,647 - Rv2068c 0.82 -0.6 2,326,814 + +1.8 2,326,815 - -0.2 2,326,815 - +0.2 2,326,815 - +1.4 2,326,817 + -1.5 2,326,818 - -0.7 2,326,818 - -0.4 2,326,818 - -0.0
Or see this region's nucleotide sequence